Max-Planck-Institut für Biophysik

Publikationen Ulrich Ermler

Zeitschriftenartikel (144)

2024

Zeitschriftenartikel

Joshi, T.; Demmer, U.; Schneider, C.; Glaser, T.; Warkentin, E.; Ermler, U.; Mack, M.: The phosphatase RosC from Streptomyces davaonensis is used for roseoflavin biosynthesis and has evolved to largely prevent dephosphorylation of the important cofactor riboflavin-5'-phosphate. Journal of Molecular Biology 436 (20), 168734 (2024)

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Zeitschriftenartikel

Gehl, M.; Demmer, U.; Ermler, U.; Shima, S.: Mutational and structural studies of (βα)₈-barrel fold methylene-tetrahydropterin reductases utilizing a common catalytic mechanism. Protein Science 33 (6), e5018 (2024)

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Zeitschriftenartikel

Aziz, I.; Kayastha, K.; Kaltwasser, S.; Vonck, J.; Welsch, S.; Murphy, B. J.; Kahnt, J.; Wu, D.; Wagner, T.; Shima, S. et al.; Ermler, U.: Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis. PNAS 121 (14), e2315568121 (2024)

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2023

Zeitschriftenartikel

Demmer, U.; Lemaire, O.; Belhamri, M.; Ermler, U.: Ethoxylate Polymer-Based 96-Well Screen for Protein Crystallization. Crystals 13, 1519 (2023)

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Zeitschriftenartikel

Gehl, M.; Demmer, U.; Ermler, U.; Shima, S.: Crystal structure of FAD-independent methylene-tetrahydrofolate reductase from Mycobacterium hassiacum. Proteins: Structure, Function, and Bioinformatics 91 (9), S. 1329 - 1340 (2023)

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2022

Zeitschriftenartikel

Vitt, S.; Prinz, S.; Eisinger, M. L.; Ermler, U.; Buckel, W.: Purification and structural characterization of the Na⁺-translocating ferredoxin: NAD⁺ reductase (Rnf) complex of Clostridium tetanomorphum. Nature Communications 13, 6315 (2022)

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Zeitschriftenartikel

Khera, R.; Mehdipour, A. R.; Bolla, J. R.; Kahnt, J.; Welsch, S.; Ermler, U.; Münke, C.; Robinson, C. V.; Hummer, G.; Xie, H. et al.; Michel, H.: Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism. The EMBO Journal 41 (18), e109990 (2022)

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Zeitschriftenartikel

Kayastha, K.; Katsyv, A.; Himmrich, C.; Welsch, S.; Schuller, J. M.; Ermler, U.; Müller, V.: Structure-based electron-confurcation mechanism of the Ldh-EtfAB complex. eLife 11, e77095 (2022)

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Zeitschriftenartikel

Aziz, I.; Kaltwasser, S.; Kayastha, K.; Khera, R.; Vonck, J.; Ermler, U.: The molybdenum storage protein forms and deposits distinct polynuclear tungsten oxygen aggregates. Journal of Inorganic Biochemistry 234, 111904 (2022)

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Zeitschriftenartikel

Weidenweber, S.; Schühle, K.; Lippert, M.-L.; Mock, J.; Seubert, A.; Demmer, U.; Ermler, U.; Heider, J.: Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyses the final step of anaerobic toluene metabolism. The FEBS Journal 5, 166 (2022)

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2021

Zeitschriftenartikel

Konia, E.; Chatzicharalampous, K.; Drakonaki, A.; Münke, C.; Ermler, U.; Tsiotis, G.; Pavlidis, I. V.: Rational engineering of Luminiphilus syltensis ( R)-selective amine transaminase for the acceptance of bulky substrates. Chemical Communications 57 (96), S. 12948 - 12951 (2021)

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Zeitschriftenartikel

Kung, J.; Meier, A.-K.; Willistein, M.; Weidenweber, S.; Demmer, U.; Ermler, U.; Boll, M.: Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem 22 (22), S. 3172 - 3177 (2021)

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Zeitschriftenartikel

Zhao, J.; Xie, H.; Mehdipour, A. R.; Safarian, S.; Ermler, U.; Münke, C.; Thielmann, Y.; Hummer, G.; Ebersberger, I.; Wang, J. et al.; Michel, H.: The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America 118 (46), e2107335118 (2021)

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Zeitschriftenartikel

Kayastha, K.; Vitt, S.; Buckel, W.; Ermler, U.: Flavins in the electron bifurcation process. Archives of Biochemistry and Biophysics 701, 108796 (2021)

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Zeitschriftenartikel

Appel, L.; Willistein, M.; Dahl, C.; Ermler, U.; Boll, M.: Functional diversity of prokaryotic HdrA(BC) modules: Role in flavin-based electron bifurcation processes and beyond. Biochimica et Biophysica Acta, Bioenergetics 1862 (4), 148379 (2021)

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Zeitschriftenartikel

Ernst, C.; Kayastha, K.; Koch , T.; Venceslau, S. S.; Pereira, I. A.C.; Demmer, U.; Ermler, U.; Dahl, C.: Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal 288 (5), S. 1664 - 1678 (2021)

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2020

Zeitschriftenartikel

Shima, S.; Huang, G.; Wagner, T.; Ermler, U.: Structural Basis of Hydrogenotrophic Methanogenesis. Annual Review of Microbiology 74, S. 713 - 733 (2020)

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Zeitschriftenartikel

Vitt, S.; Prinz, S.; Hellwig, N.; Morgner, N.; Ermler, U.; Buckel, W.: Molecular and Low-Resolution Structural Characterization of the Na+-Translocating Glutaconyl-CoA Decarboxylase From Clostridium symbiosum. Frontiers in Microbiology 11, 480 (2020)

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Zeitschriftenartikel

Huang, G.; Wagner, T.; Demmer, U.; Warkentin, E.; Ermler, U.; Shima, S.: The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. Journal of Molecular Biology (London) 432 (7), S. 2042 - 2054 (2020)

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Zeitschriftenartikel

Huang, G.; Wagner, T.; Ermler, U.; Shima, S.: Methanogenesis involves direct hydride transfer from H₂ to an organic substrate. Nature Reviews Chemistry 4 (2), S. 213 - 221 (2020)

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2019

Zeitschriftenartikel

Brünle, S.; Eisinger, M. L.; Poppe, J.; Mills, D. J.; Langer, J. D.; Vonck, J.; Ermler, U.: Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism. Proceedings of the National Academy of Sciences of the United States of America 52 (116), S. 26497 - 26504 (2019)

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Zeitschriftenartikel

Huang, G.; Wagner, T.; Wodrich, M. D.; Ataka, K.; Bill, E.; Ermler, U.; Hu, X.; Shima, S.: The atomic-resolution crystal structure of activated [Fe]-hydrogenase. Nature Catalysis 2 (6), S. 537 - 543 (2019)

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Zeitschriftenartikel

Willistein, M.; Bechtel, D. F.; Müller, C. S.; Demmer, U.; Heimann, L.; Kayastha, K.; Schünemann, V.; Pierik, A. J.; Ullmann, G. M.; Ermler, U. et al.; Boll, M.: Low potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactorsLow potential enzymatic hydride transfer via highly cooperative and inversely functionalized flavin cofactors. Nature Communications 10, 2074 (2019)

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Zeitschriftenartikel

Watanabe, T.; Wagner, T.; Huang, G.; Kahnt, J.; Ataka, K.; Ermler, U.; Shima, S.: The Bacterial [Fe]‐Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates. Angewandte Chemie International Edition in English 58 (11), S. 3506 - 3510 (2019)

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2018

Zeitschriftenartikel

Poppe, J.; Brünle, S.; Hail, R.; Wiesemann, K.; Schneider, K.; Ermler, U.: The Molybdenum Storage Protein: A soluble ATP hydrolysis‐dependent molybdate pump. The FEBS Journal 285 (24), S. 4602 - 4616 (2018)

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Zeitschriftenartikel

Brünle, S.; Poppe, J.; Hail, R.; Demmer, U.; Ermler, U.: The molybdenum storage protein - A bionanolab for creating experimentally alterable polyoxomolybdate clusters. Journal of Inorganic Biochemistry 189 (12), S. 172 - 179 (2018)

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Zeitschriftenartikel

Wagner , T.; Huang, G.; Ermler, U.; Shima, S.: How [Fe]-Hydrogenase from Methanothermobacter is Protected Against Light and Oxidative Stress. Angewandte Chemie International Edition in English 57 (46), S. 15056 - 15059 (2018)

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Zeitschriftenartikel

Huang, G.; Wagner, T.; Ermler, U.; Bill, E.; Ataka, K.; Shima, S.: Dioxygen Sensitivity of [Fe]‐Hydrogenase in the Presence of Reducing Substrates. Angewandte Chemie International Edition in English 57 (18), S. 4917 - 4920 (2018)

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Zeitschriftenartikel

Demmer, J. K.; Bertsch, J.; Öppinger, C.; Wohlers, H.; Kayastha, K.; Demmer, U.; Ermler, U.; Müller, V.: Molecular basis of the flavin‐based electron‐bifurcating caffeyl‐CoA reductase reaction. FEBS Letters 592 (3), S. 332 - 342 (2018)

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2017

Zeitschriftenartikel

Demmer, J. K.; Chowdhury, N. P.; Selmer, T.; Ermler, U.; Buckel, W.: The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile. Nature Communications 8, 1577 (2017)

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Zeitschriftenartikel

Warkentin, E.; Weidenweber, S.; Schühle, K.; Demmer, U.; Heider, J.; Ermler, U.: A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins: Structure, Function, and Bioinformatics 85 (11), S. 2017 - 2023 (2017)

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Zeitschriftenartikel

Weinert, T.; Olieric, N.; Cheng, R.; Brünle, S.; James, D.; Ozerov, D.; Gashi, D.; Vera, L.; Marsh, M.; Jaeger, K. et al.; Dworkowski, F.; Panepucci, E.; Basu, S.; Skopintsev, P.; Dorè, A. S.; Geng, T.; Cooke, R. M.; Liang, M.; Prota, A. E.; Paneels, V.; Nogly, P.; Ermler, U.; Schertler, G.; Hennig, M.; Steinmetz, M. O.; Wang, M.; Standfuss, J.: Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nature Communications 8, 542 (2017)

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Zeitschriftenartikel

Bai, L.; Wagner, T.; Xu, T.; Hu, X.; Ermler, U.; Shima, S.: A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angewandte Chemie, International Edition in English 56 (36), S. 10806 - 10809 (2017)

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Zeitschriftenartikel

Wagner, T.; Koch, J.; Ermler, U.; Shima, S.: Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science 357 (6352), S. 699 - 703 (2017)

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Zeitschriftenartikel

Bai, L.; Fujishiro, T.; Huang, G.; Koch , J.; Takabayashi, A.; Yokono , M.; Tanaka , A.; Xu, T.; Hu , X.; Ermler, U. et al.; Shima , S.: Towards artificial methanogenesis: biosynthesis of the [Fe]-hydrogenase cofactor and characterization of the semi-synthetic hydrogenase. Faraday Discussions 198 (37), S. 37 - 58 (2017)

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Zeitschriftenartikel

Konjik, V.; Brünle, S.; Demmer, U.; Vanselow, A.; Sandhoff, R.; Ermler, U.; Mack, M.: The Crystal Structure of RosB: Insights into the Reaction Mechanism of the First Member of a Family of Flavodoxin-like Enzymes. Angewandte Chemie, International Edition in English 56 (4), S. 1146 - 1151 (2017)

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Zeitschriftenartikel

Weidenweber, S.; Schühle, K.; Demmer, U.; Warkentin, E.; Ermler, U.; Heider, J.: Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Scientific Reports 7, 39674 (2017)

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2016

Zeitschriftenartikel

Demmer, J. K.; Rupprecht, F. A.; Eisinger, M. L.; Ermler, U.; Langer, J. D.: Ligand binding and conformational dynamics in a flavin-based electron-bifurcating enzyme complex revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. FEBS Letters 590 (24), S. 4472 - 4479 (2016)

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Zeitschriftenartikel

Wagner , T.; Ermler, U.; Shima, S.: The methanogenic CO₂ reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters. Science Magazine 354 (6308), S. 114 - 117 (2016)

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Zeitschriftenartikel

Upadhyay, V.; Ceh, K.; Tumulka, F.; Abele, R.; Hoffmann , J.; Langer, J. D.; Shima, S.; Ermler, U.: Molecular characterization of methanogenic N⁵-methyltetrahydromethanopterin: Coenzyme M methyltransferase. Biochimica et Biophysica Acta-Biomembranes 1858 (9), S. 2140 - 2144 (2016)

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Zeitschriftenartikel

Wagner, T.; Kahnt, J.; Ermler, U.; Shima, S.: Didehydroaspartate Modification in Methyl-Coenzyme M Reductase Catalyzing Methane Formation. Angewandte Chemie International Edition in English 55 (36), S. 10630 - 10633 (2016)

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Zeitschriftenartikel

Fujishiro, T.; Bai , L.; Xu , T.; Xie , X.; Schick, M.; Kahnt, J.; Rother, M.; Hu , X.; Ermler, U.; Shima, S.: Identification of HcgC as a SAM-Dependent Pyridinol Methyltransferase in [Fe]-Hydrogenase Cofactor Biosynthesis. Angewandte Chemie International Edition in English 55 (33), S. 9648 - 9651 (2016)

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Zeitschriftenartikel

Wagner, T.; Ermler, U.; Shima, S.: MtrA of the sodium ion pumping methyltransferase binds cobalamin in a unique mode. Scientific Reports 6, 28226 (2016)

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Zeitschriftenartikel

Weidenweber, S.; Marmulla, R.; Ermler, U.; Harder, J.: X-ray structure of linalool dehydratase/isomerase from Castellaniella defragrans reveals enzymatic alkene synthesis. FEBS Letters 590 (9), S. 1375 - 1383 (2016)

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Zeitschriftenartikel

Boll, M.; Einsle, O.; Ermler, U.; Kroneck, P. M.H.: Structure and Function of the Unusual Tungsten Enzymes Acetylene Hydratase and Class II Benzoyl-Coenzyme A Reductase. Journal of Molecular Microbiology and Biotechnology 26 (1-3), S. 119 - 137 (2016)

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Zeitschriftenartikel

Boll, M.; Kung, J. W.; Ermler, U.; Martins, B. M.; Buckel, W.: Fermentative Cyclohexane Carboxylate Formation in Syntrophus aciditrophicus. Journal of Molecular Microbiology and Biotechnology 26 (1-3), S. 165 - 179 (2016)

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Zeitschriftenartikel

Rabus, R.; Boll , M.; Heider, J.; Meckenstock, R. U.; Buckel, W.; Einsle, O.; Ermler, U.; Golding, B. T.; Gunsalus, R. P.; Kroneck, P. M.H. et al.; Krüger, M.; Lueders, T.; Martins, B. M.; Musat, F.; Richnow, H. H.; Schink, B.; Seifert, J.; Szaleniec, M.; Treude, T.; Ullmann, G. M.; Vogt, C.; von Bergen, M.; Wilkes, H.: Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment. Journal of Molecular Microbiology and Biotechnology 26 (1-3), S. 5 - 28 (2016)

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2015

Zeitschriftenartikel

Demmer, J. K.; Huang, H.; Wang, S.; Demmer, U.; Thauer, R. K.; Ermler, U.: Insights into Flavin-based Electron Bifurcation via the NADH-dependent Reduced Ferredoxin:NADP Oxidoreductase Structure. The Journal of Biological Chemistry 290 (36), S. 21985 - 21885 (2015)

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Zeitschriftenartikel

Fujishiro, T.; Ataka, K.; Ermler, U.; Shima, S.: Towards a functional identification of catalytically inactive [Fe]-hydrogenase paralogs. FEBS Journal 282 (17), S. 3412 - 3423 (2015)

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Zeitschriftenartikel

Weinert, T.; Huwiler, S.; Kung, J. W.; Weidenweber, S.; Hellwig, P.; Stärk, H.-J.; Biskup, T.; Weber, S.; Cotelesage, J. J.H.; George, G. N. et al.; Ermler, U.; Boll, M.: Structural basis of enzymatic benzene ring reduction. Nature Chemical Biology 11 (8), S. 586 - 591 (2015)

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Zeitschriftenartikel

Fujishiro, T.; Kahnt, J.; Ermler, U.; Shima, S.: Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor. Nature Communications 6, e6895 (2015)

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Zeitschriftenartikel

Rekittke, I.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the GcpE-HMBPP complex from Thermus thermophilius. Biochemical and Biophysical Research Communications 458 (2), S. 246 - 250 (2015)

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2014

Zeitschriftenartikel

Poppe, J.; Warkentin, E.; Demmer, U.; Kowalewski, B.; Dierks, T.; Schneider, K.; Ermler, U.: Structural diversity of polyoxomolybdate clusters along the three-fold axis of the molybdenum storage protein. Journal of Inorganic Biochemistry 138, S. 122 - 128 (2014)

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Zeitschriftenartikel

Fujishiro, T.; Ermler, U.; Shima, S.: A possible iron delivery function of the dinuclear iron center of HcgD in [Fe]-hydrogenase cofactor biosynthesis. FEBS Letters 588 (17), S. 2789 - 2793 (2014)

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Zeitschriftenartikel

Vitt, S.; Ma, K.; Warkentin, E.; Moll, J.; Pierik, A. J.; Shima, S.; Ermler, U.: The F₄₂₀-Reducing [NiFe]-Hydrogenase Complex from Methanothermobacter marburgensis, the First X-ray Structure of a Group 3 Family Member. Journal of Molecular Biology (London) 426 (15), S. 2813 - 2826 (2014)

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Zeitschriftenartikel

Buschmann, S.; Richers, S.; Ermler, U.; Michel, H.: A decade of crystallization drops: Crystallization of the cbb₃ cytochrome c oxidase from Pseudomonas stutzeri. Protein Science 23 (4), S. 411 - 422 (2014)

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Zeitschriftenartikel

Chowdhury, N. P.; Mowafy, A. M.; Demmer, J. K.; Upadhyay, V.; Koelzer, S.; Jayamani, E.; Kahnt, J.; Hornung, M.; Demmer, U.; Ermler, U. et al.; Buckel, W.: Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans. The Journal of Biological Chemistry 289 (8), S. 5145 - 5157 (2014)

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2013

Zeitschriftenartikel

Rekittke, I.; Olkhova, E.; Wiesner, J.; Demmer, U.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the (E)-4-hydroxy-3-methyl-but-2-enyl-diphosphate reductase from Plasmodium falciparum. FEBS Letters 587 (24), S. 3968 - 3972 (2013)

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Zeitschriftenartikel

Fielding, A. J.; Parey, K.; Ermler, U.; Scheller, S.; Jaun, B.; Bennati, M.: Advanced electron paramagnetic resonance on the catalytic iron–sulfur cluster bound to the CCG domain of heterodisulfide reductase and succinate: quinone reductase. Journal of Biological Inorganic Chemistry 18 (8), S. 905 - 915 (2013)

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Zeitschriftenartikel

Fujishiro, T.; Tamura, H.; Schick, M.; Kahnt, J.; Xie, X.; Ermler, U.; Shima, S.: Identification of the HcgB Enzyme in [Fe]-Hydrogenase-Cofactor Biosynthesis. Angewandte Chemie, International Edition in English 52 (48), S. 12555 - 12558 (2013)

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Zeitschriftenartikel

Parey, K.; Demmer, U.; Warkentin, E.; Wynen, A.; Ermler, U.; Dahl, C.: Structural, Biochemical and Genetic Characterization of Dissimilatory ATP Sulfurylase from Allochromatium vinosum. PLoS One 8 (9), S. e74707 - e74707 (2013)

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Zeitschriftenartikel

Tamura, H.; Salomone-Stagni, M.; Fujishiro, T.; Warkentin, E.; Meyer-Klaucke, W.; Ermler, U.; shima, S.: Crystal Structures of [Fe]-Hydrogenase in Complex with Inhibitory Isocyanides: Implications for the H₂-Activation Site. Angewandte Chemie, International Edition in English 52 (37), S. 9656 - 9659 (2013)

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Zeitschriftenartikel

Parey, K.; Fritz, G.; Ermler, U.; Kroneck, P. M. H.: Conserving energy with sulfate around 100 °C - structure and mechanism of key metal enzymes in hyperthermophilic Archaeoglobus fulgidus. Metallomics 5 (4), S. 302 - 317 (2013)

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Zeitschriftenartikel

Demmer, U.; Warkentin, E.; Srivastava, A.; Kockelkorn, D.; Pötter, M.; Marx, A.; Fuchs, G.; Ermler, U.: Structural Basis for a Bispecific NADP⁺ and CoA Binding Site in an Archaeal Malonyl-Coenzyme A Reductase. The Journal of Biological Chemistry 288 (9), S. 6363 - 6370 (2013)

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2012

Zeitschriftenartikel

El Hammi, E.; Warkentin, E.; Demmer, U.; Marzouki, N. M.; Ermler, U.; Baciou, L.: Active site analysis of yeast flavohemoglobin based on its structure with a small ligand or econazole. The FEBS Journal 279 (24), S. 4565 - 4575 (2012)

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Zeitschriftenartikel

Upadhyay, V.; Demmer, U.; Warkentin, E.; Moll, J.; Shima, S.; Ermler, U.: Structure and Catalytic Mechanism of N⁵,N¹⁰-Methenyltetrahydromethanopterin Cyclohydrolase. Biochemistry 51 (42), S. 8435 - 8443 (2012)

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Zeitschriftenartikel

Rekittke, I.; Jomaa, H. H.; Ermler, U.: Structure of the GcpE (IspG)-MEcPP complex from Thermus thermophilus. FEBS Letters 586 (19), S. 3452 - 3457 (2012)

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Zeitschriftenartikel

Shima, S.; Ermler, U.: Crystal structure and biochemistry of methyl-coenzyme M reductase from Black Sea mats mediating anaerobic oxidation of methane. Biseibutsu Seitai 27 (2), S. 55 - 62 (2012)

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Zeitschriftenartikel

Kowalewski, B.; Poppe, J.; Demmer, U.; Warkentin, E.; Dierks, T.; Ermler, U.; Schneider, K.: Nature’s Polyoxometalate Chemistry: X-ray Structure of the Mo Storage Protein Loaded with Discrete Polynuclear Mo−O Clusters. The Journal of Physical Chemistry A 134 (23), S. 9768 - 9774 (2012)

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Zeitschriftenartikel

Steinbach, A.; Fraas, S.; Harder, J.; Warkentin, E.; Kroneck, P. M. H.; Ermler, U.: Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family. The FEBS Journal 279 (7), S. 1209 - 1219 (2012)

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Zeitschriftenartikel

Shima, S.; Krueger, M.; Weinert, T.; Demmer, U.; Kahnt, J.; Thauer, R. K.; Ermler, U.: Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically. Nature 481 (7379), S. 98 - 101 (2012)

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2011

Zeitschriftenartikel

Steinbach, A. K.; Fraas, S.; Harder, J.; Tabbert, A.; Brinkmann, H.; Meyer, A.; Ermler, U.; Kroneck, P. M. H.: Cyclohexane-1,2-Dione Hydrolase from Denitrifying Azoarcus sp. Strain 22Lin, a Novel Member of the Thiamine Diphosphate Enzyme Family. Journal of Bacteriology 193 (23), S. 6760 - 6769 (2011)

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Zeitschriftenartikel

Rather, L. J.; Weinert, T.; Demmer, U.; Bill, E.; Ismail, W.; Fuchs, G.; Ermler, U.: Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB. The Journal of Biological Chemistry 286 (33), S. 29241 - 29248 (2011)

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Zeitschriftenartikel

Shima, S.; Ermler, U.: Structure and Function of [Fe]-Hydrogenase and its Iron–Guanylylpyridinol (FeGP) Cofactor. European Journal of Inorganic Chemistry 2011 (7), S. 963 - 972 (2011)

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Zeitschriftenartikel

Barthelme, D.; Dinkelaker, S.; Albers, S.-V.; Londei, P.; Ermler, U.; Tampé, R.: Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1. Proceedings of the National Academy of Sciences of the United States of America 108 (8), S. 3228 - 3233 (2011)

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Zeitschriftenartikel

El Hammi, E.; Warkentin, E.; Demmer, U.; Limam, F.; Marzouki, N. M.; Ermler, U.; Baciou, L.: Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds. Biochemistry 50 (7), S. 1255 - 1264 (2011)

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Zeitschriftenartikel

Rekittke, I.; Nonaka, T.; Wiesner, J.; Demmer, U.; Warkentin, E.; Jomaa, H.; Ermler, U.: Structure of the E-1-hydroxy-2-methyl-but-2-enyl-4-diphosphate synthase (GcpE) from Thermus thermophilus. FEBS Letters 585 (3), S. 447 - 451 (2011)

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2010

Zeitschriftenartikel

Parey, K.; Warkentin, E.; Kroneck, P. M.; Ermler, U.: Reaction Cycle of the Dissimilatory Sulfite Reductase from Archaeoglobus fulgidus. Biochemistry 49 (41), S. 8912 - 8921 (2010)

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Zeitschriftenartikel

Buschmann, S.; Warkentin, E.; Xie, H.; Langer, J. D.; Ermler, U.; Michel, H.: The Structure of cbb₃ Cytochrome Oxidase Provides Insights into Proton Pumping. Science 329 (5989), S. 327 - 330 (2010)

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Zeitschriftenartikel

Rajendran, C.; Ermler, U.; Ludwig, B.; Michel, H.: Structure at 1.5 Å resolution of cytochrome c₅₅₂ with its flexible linker segment, a membrane-anchored protein from Paracoccus denitrificans. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D66 (7), S. 850 - 854 (2010)

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Zeitschriftenartikel

Wischgoll, S.; Demmer, U.; Warkentin, E.; Günther, R.; Boll, M.; Ermler, U.: Structural Basis for Promoting and Preventing Decarboxylation in Glutaryl-Coenzyme A Dehydrogenases. Biochemistry 49 (25), S. 5350 - 5357 (2010)

MPG.PuRe

Zeitschriftenartikel

Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: A new structure-based classification of sulfide:quinone oxidoreductases. Proteins: Structure, Function, and Bioinformatics 78 (5), S. 1073 - 1083 (2010)

MPG.PuRe

2009

Zeitschriftenartikel

Fraas, S.; Steinbach, A. K.; Tabbert, A.; Harder, J.; Ermler, U.; Tittmann, K.; Meyer, A.; Kroneck, P. M.H.: Cyclohexane-1,2-dione hydrolase: A new tool to degrade alicyclic compounds. Journal of Molecular Catalysis B: Enzymatic 61 (1-2), S. 47 - 49 (2009)

MPG.PuRe

Zeitschriftenartikel

Ceh, K.; Demmer, U.; Warkentin, E.; Moll, J.; Thauer, R. K.; Shima, S.; Ermler, U.: Structural Basis of the Hydride Transfer Mechanism in F₄₂₀-Dependent Methylenetetrahydromethanopterin Dehydrogenase. Biochemistry 49 (42), S. 10098 - 10105 (2009)

MPG.PuRe

Zeitschriftenartikel

Hiromoto, T.; Warkentin, E.; Moll, J.; Ermler, U.; Shima, S.: The Crystal Structure of an [Fe]-Hydrogenase-Substrate Complex Reveals the Framework for H₂ Activation. Angewandte Chemie, International Edition in English 48 (35), S. 6457 - 6460 (2009)

MPG.PuRe

Zeitschriftenartikel

Marcia, M.; Ermler, U.; Peng, G.; Michel, H.: The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. Proceedings of the National Academy of Sciences of the United States of America 106 (24), S. 9625 - 9630 (2009)

MPG.PuRe

Zeitschriftenartikel

Hiromoto, T.; Ataka, K.; Pilak, O.; Vogt, S.; Stagni, M. S.; Meyer-Klaucke, W.; Warkentin, E.; Thauer, R. K.; Shima, S.; Ermler, U.: The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex. FEBS Letters 583 (3), S. 585 - 590 (2009)

MPG.PuRe

2008

Zeitschriftenartikel

Shima, S.; Pilak, O.; Vogt, S.; Schick, , M.; Stagni, M. S.; Meyer-Klauke, W.; Warkentin, E.; Thauer, R. K.; Ermler, U.: The Crystal Structure of [Fe]-Hydrogenase Reveals the Geometry of the Active Site. Science 321 (5888), S. 572 - 575 (2008)

MPG.PuRe

Zeitschriftenartikel

Schiffer, A.; Parey, K.; Warkentin, E.; Diederichs, K.; Huber, H.; Stetter, K. O.; Kroneck, P. M. H.; Ermler, U.: Structure of the Dissimilatory Sulfite Reductase from the Hyperthermophilic Archaeon Archaeoglobus fulgidus. Journal of Molecular Biology (London) 379 (5), S. 1063 - 1074 (2008)

MPG.PuRe

Zeitschriftenartikel

Jörg, J.; Unciuleac, M.-C.; Friedrich, T.; Warkentin, E.; Ermler, U.; Boll, M.: Inhibitors of the Molybdenum Cofactor Containing 4-Hydroxybenzoyl-CoA Reductase. Biochemistry 47 (17), S. 4964 - 4972 (2008)

MPG.PuRe

2007

Zeitschriftenartikel

Schemberg, J.; Schneider, K.; Demmer, U.; Warkentin, E.; Müller, A.; Ermler, U.: Towards Biological Supramolecular Chemistry: A Variety of Pocket-Templated Metal Oxide Cluster Nucleations in the Cavity of a Mo/W-Storage Protein. Angewandte Chemie, International Edition in English 46 (14), S. 2408 - 2413 (2007)

MPG.PuRe

Zeitschriftenartikel

Seedorf, H.; Hagemeier, C. H.; Shima, S.; Thauer, R. K.; Warkentin, E.; Ermler, U.: Structure of coenzyme F₄₂₀H₂ oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalysing the reduction of O₂ to H₂O. The FEBS Journal 274 (6), S. 1588 - 1599 (2007)

MPG.PuRe

Zeitschriftenartikel

de Olivereira, P.; Ranjbari, A.; Baciou, L.; Bizouarn, T.; Ollesch, G.; Ermler, U.; Sebban, P.; Keita, B.; Nadjo, L.: Preliminary electrochemical studies of the flavohaemoprotein from Ralstonia eutropha entrapped in a film of methyl cellulose: activation of the reduction of dioxygen. Bioelectrochemistry 70 (1), S. 185 - 191 (2007)

MPG.PuRe

2006

Zeitschriftenartikel

Hagemeier, C. H.; Krüer, M.; Thauer, R.; Warkentin, E.; Ermler, U.: Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex. Proceedings of the National Academy of Sciences of the United States of America 103 (50), S. 18917 - 18922 (2006)

MPG.PuRe

Zeitschriftenartikel

Pilak, O.; Mamat, B.; Vogt, S.; Hagemeier, C. H.; Thauer, R. K.; Shima, S.; Vonrhein, C.; Warkentin, E.; Ermler, U.: The Crystal Structure of the Apoenzyme of the Iron-Sulphur Cluster-free Hydrogenase. Journal of Molecular Biology (London) 358 (3), S. 798 - 809 (2006)

MPG.PuRe

Zeitschriftenartikel

Acharya, P.; Warkentin, E.; Ermler, U.; Thauer, R. K.; Shima, S.: The structure of a Formylmethanofuran: Tetrahydromethanopterin Formyltransferase in Complex with its Coenzymes. Journal of Molecular Biology (London) 357 (3), S. 870 - 879 (2006)

MPG.PuRe

Zeitschriftenartikel

Schiffer, A.; Fritz, G.; Kroneck, P. M.H.; Ermler, U.: Reaction Mechanism of the Iron-Sulfur Flavoenzyme Adenosine-5 '-Phosphosulfate Reductase Based on the Structural Characterization of Different Enzymatic States. Biochemistry 45 (9), S. 2960 - 2967 (2006)

MPG.PuRe

2005

Zeitschriftenartikel

Mander, G. J.; Weiss, M. S.; Hedderich, R.; Kahnt, J.; Ermler, U.; Warkentin, E.: X-ray structure of the γ-subunit of a dissimilatory sulfite reductase: Fixed and flexible C-terminal arms. FEBS Letters 579 (21), S. 4600 - 4604 (2005)

MPG.PuRe

Zeitschriftenartikel

Aufhammer, S. W.; Warkentin, E.; Ermler, U.; Hagemeier, C. H.; Thauer, R. K.; Shima, S.: Crystal structure of methylenetetrahydromethanopterin (Mer) in complex with coenzyme F₄₂₀: Architecture of the F₄₂₀/FMN binding site of enzymes within the nonprolyl cis-peptide containing bacterial luciferase family. Protein Science 14 (7), S. 1840 - 1849 (2005)

MPG.PuRe