Publikationen von Ulrich Ermler

Acharya, P.; Gornrich, M.; Hagemeier, C.; Vorholt, J. A.; Thauer, R. K.; Ermler, U.: How an Enzyme Binds the C₁ Carrier Tetrahydromethanopterin. Structure of the Tetrahydromethanopterin-Dependent Formaldehyde-Activating Enzyme (Fae) from Methylobacterium extorquens AM1. The Journal of Biological Chemistry 280 (14), S. 13712 - 13719 (2005)

Ermler, U.: On the mechanism of methyl-coenzyme M reductase. Dalton Transactions 21, S. 3451 - 3458 (2005)

Warkentin, E.; Hagemeier, C.; Shima, S.; Thauer, R. K.; Ermler, U.: The structure of F₄₂₀-dependent methylenetetrahydromethanopterin dehydrogenase: a crystallographic 'superstructure' of the selenomethionine-labelled protein crystal structure. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen), S. 198 - 202 (2005)

Unciuleac, M.; Warkentin, E.; Page, C. C.; Boll, M.; Ermler, U.: Structure of Xanthine Oxidase-Related 4-Hydroxybenzoyl-CoA Reductase with an Additional [4Fe-4S] Cluster and an Inverted Electron Flow. Structure 12 (12), S. 2249 - 2256 (2004)

Aufhammer, S. W.; Warkentin, E.; Berk, H.; Shima, S.; Thauer, R. K.; Ermler, U.: Coenzyme binding in F₄₂₀-dependent secondary alcohol dehydrogenase, a member of the bacterial luciferase family. Structure 12 (3), S. 361 - 370 (2004)

Unciuleac, M.; Boll, M.; Warkentin, E.; Ermler, U.: Crystallization of 4-hydroxybenzoyl-CoA reductase and the structure of its electron donor ferredoxin. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 60, S. 388 - 391 (2004)

Weiss, M. S.; Mander, G.; Hedderich, R.; Diederichs, K.; Ermler, U.; Warkentin, E.: Protein structure determination by a combination of long wavelength sulphur phasing and radiation damage induced phasing. Acta Crystallographica Section D-Biological Crystallography D60, S. 686 - 695 (2004)

Mamat, B.; Roth, A.; Grimm, C.; Ermler, U.; Tziatzios, C.; Schubert, D.; Thauer, R. K.; Shima, S.: Crystal structures and enzymatic properties of three formyltransferases from archaea: Environmental adaptation and evolutionary relationship. Protein Science 11 (9), S. 2168 - 2178 (2002)

Ermler, U.; Hagemeier, C. H.; Roth, A.; Demmer, U.; Grabarse, W.; Warkentin, E.; Vorhott, J. A.: Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylobacterium extorquens AM1. Structure 10 (8), S. 1127 - 1137 (2002)

Shima, S.; Warkentin, E.; Thauer, R. K.; Ermler, U.: Structure and function of enzymes involved in the methanogenic pathway utilizing carbon dioxide and molecular hydrogen [Review]. Journal of Bioenergetics and Biomembranes 93 (6), S. 519 - 530 (2002)

Fritz, G.; Roth, A.; Schiffer, A.; Buchert, T.; Bourenkov, G.; Bartunik, H. D.; Huber, H.; Stetter, K. O.; Kroneck, P. M. H.; Ermler, U.: Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6-Å resolution. Proceedings of the National Academy of Sciences of the United States of America 99 (4), S. 1836 - 1841 (2002)

Warkentin, E.; Mamat, B.; Sordel-Klippert, M.; Wicke, M.; Thauer, R. K.; Iwata, M.; Iwata, S.; Ermler, U.; Shima, S.: Structures of F₄₂₀H²:NADP⁺ oxidoreductase with and without its substrates bound. The EMBO Journal 20 (23), S. 6561 - 6569 (2001)

Grabarse, W.; Mahlert, F.; Duin, E. C.; Goubeaud, M.; Shima, S.; Thauer, R. K.; Lamzin, V.; Ermler, U.: On the mechanism of biological methane formation: structural evidence for conformational changes in methyl-coenzyme M reductase upon substrate binding. Journal of Molecular Biology (London) 309 (1), S. 315 - 330 (2001)

Kuglstatter, A.; Ermler, U.; Michel, H.; Baciou, L.; Fritzsch, G.: X-ray Structure Analyses of Photosynthetic Reaction Center Variants from Rhodobacter sphaeroides:  Structural Changes Induced by Point Mutations at Position L209 Modulate Electron and Proton Transfer. Biochemistry 40 (14), S. 4253 - 4260 (2001)

Roth, A.; Fritz, G.; Büchert, T.; Huber, H.; Stetter, K. O.; Ermler, U.; Kroneck, P. M.H.: Crystallization and preliminary X-ray analysis of adenylylsulfate reductase from Archaeoglobus fulgidus. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D56 (12), S. 1673 - 1675 (2000)

Shima, S.; Thauer, R. K.; Ermler, U.; Durchschlag, H.; Tziatzios, .; Schubert, D.: A mutation affecting the dimer/tetramer association equilibrium of formyltransferase from the hyperthermophilic Methanopyrus kandleri in relation to the activity and thermostability of the enzyme. European Journal of Biochemistry 267 (22), S. 6619 - 6623 (2000)

Grabarse, W.; Mahlert, F.; Shima , S.; Thauer, R. K.; Ermler, U.: Comparison of three methyl-coenzyme M reductases from phylogenetically distant organisms: unusual amino acid modification, conservation and adaptation. Journal of Molecular Biology (London) 303 (2), S. 329 - 344 (2000)

Shima, S.; Warkentin, E.; Grabarse, W.; Sordel, M.; Wicke, M.; Thauer, R. K.; Ermler, U.: Structure of coenzyme F₄₂₀ dependent methylenetetrahydromethanopterin reductase from two methanogenic archaea. Journal of Molecular Biology (London) 300 (4), S. 935 - 950 (2000)

Koepke, J.; Ermler, U.; Warkentin, E.; Wenzl, G.; Flecker, P.: Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 å resolution. Structural basis of Janus-faced serine protease inhibitor specificity. Journal of Molecular Biology (London) 298 (3), S. 477 - 491 (2000)

Selmer, T.; Kahnt, J.; Goubeaud, M.; Shima, S.; Grabarse, W.; Ermler, U.; Thauer, R. K.: The Biosynthesis of Methylated Amino Acids in the Active Site Region of Methyl-coenzyme M Reductase. The Journal of Biological Chemistry 275 (6), S. 3755 - 3760 (2000)

Grabarse, W.; Vaupel, M.; Vorholt, J. A.; Shima, S.; Thauer, R. K.; Wittershagen, A.; Bourenkov, G.; Bartunik, H. D.; Ermler, U.: The crystal structure of methenyltetrahydromethanopterin cyclohydrolase from the hyperthermophilic archaeon Methanopyrus kandleri. Structure 7 (10), S. 1257 - 1268 (1999)

Ollesch, G.; Kaunzinger, A.; Juchelka, D.; Schubert-Zsilavecz, M.; Ermler, U.: Phospholipid bound to the flavohemoprotein from Alcaligenes eutrophus. European Journal of Biochemistry 262 (2), S. 396 - 405 (1999)

Schmees, G.; Höner zu Bentrup, K.; Schneider, E.; Vinzenz, D.; Ermler, U.: Crystallization and preliminary X-ray analysis of the bacterial ATP-binding-cassette (ABC) protein MalK. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) 55 (1), S. 285 - 286 (1999)

Ermler, U.; Grabarse, W.; Shima, S.; Goubeaud, M.; Thauer, R. K.: Active sites of transition-metal enzymes with a focus on nickel. Current Opinion in Structural Biology 8 (6), S. 749 - 758 (1998)

Shima, S.; Tziatzios, C.; Schubert, D.; Fukada, H.; Takahashi, K.; Ermler, U.; Thauer, R. K.: Lyotropic‐salt‐induced changes in monomer/dimer/tetramer association equilibrium of formyltransferase from the hyperthermophilic Methanopyrus kandleri in relation to the activity and thermostability of the enzyme. European Journal of Biochemistry 258 (1), S. 85 - 92 (1998)

Ermler, U.; Grabarse, W.; Shima, S.; Goubeaud, M.; Thauer, R. K.: Crystal structure of methyl-coenzyme M reductase: the key enzyme of biological methane formation. Science 278 (5342), S. 1457 - 1462 (1997)

Ostermeier, C.; Harrenga, A.; Ermler, U.; Michel, H.: Structure at 2.7 Å resolution of the Paracoccus denitrificans two subunit cytochrome c oxidase complexed with an antibody F_v fragment. Proceedings of the National Academy of Sciences of the United States of America 94 (20), S. 10547 - 10553 (1997)

Ermler, U.; Merckel, M. C.; Thauer, R. K.; Shima, S.: Formylmethanofuran: tetrahydromethanopterin formyltransferase from Methanopyrus kandleri — new insights into salt-dependence and thermostability. Structure 5 (5), S. 635 - 646 (1997)

Shima, S.; Goubeaud , M.; Vinzenz, D.; Thauer, R. K.; Ermler, U.: Crystallization and preliminary X-ray diffraction studies of methyl-coenzyme M reductase from methanobacterium thermoautotrophicum. Journal of Biochemistry 121 (5), S. 829 - 830 (1997)

Feick, R.; Ertlmaier, A.; Ermler, U.: Crystallization and X-ray analysis of the reaction center from the thermophilic green bacterium Chloroflexus aurantiacus. FEBS Letters 396 (2-3), S. 161 - 164 (1996)

Voss, R.-H.; Ermler, U.; Essen, L.-O.; Wenzl, G.; Kim, Y.; Flecker, P.: Crystal Structure of the Bifunctional Soybean Bowman‐Birk Inhibitor at 0.28‐nm Resolution. European Journal of Biochemistry 242 (1), S. 122 - 131 (1996)

Shima, S.; Thauer, R. K.; Michel, H.; Ermler, U.: Crystallization and preliminary X‐ray diffraction studies of formylmethanofuran: Tetrahydromethanopterin formyltransferase from Methanopyrus kandleri. Proteins: Structure, Function, and Bioinformatics 26 (1), S. 118 - 120 (1996)

Apostolakis, J.; Muegge, I.; Ermler, U.; Fritzsch, G.; Knapp, E.W.: Free Energy Computations on the Shift of the Special Pair Redox Potential:  Mutants of the Reaction Center of Rhodobacter sphaeroides. Journal of the American Chemical Society 118 (15), S. 3743 - 3752 (1996)

Muegge, I.; Apostolakis, J.; Ermler, U.; Fritzsch, G.; Lubitz, W.; Knapp, E.W.: Shift of the Special Pair Redox Potential:  Electrostatic Energy Computations of Mutants of the Reaction Center from Rhodobacter sphaeroides. Biochemistry 35 (25), S. 8359 - 8370 (1996)

Ermler, U.; Siddiqui, R. A.; Cramm, R.; Friedrich, B.: Crystal structure of the flavohemoglobin from Alcaligenes eutrophus at 1.75 A resolution. The EMBO Journal 14 (24), S. 6067 - 6077 (1995)

Ermler, U.; Siddiqui, R. A.; Cramm, R.; Schröder, D.; Friedrich , B.: Crystallization and preliminary X‐ray diffraction studies of a bacterial flavohemoglobin protein. Proteins: Structure, Function, and Bioinformatics 21 (4), S. 351 - 353 (1995)

Muegge, I.; Ermler, U.; Fritzsch, G.; Knapp, E. W.: Free Energy of Cofactors at the Quinone-Q_A Site of the Photosynthetic Reaction Center of Rhodobacter sphaeroides Calculated by Minimizing the Statistical Error. The Journal of Physical Chemistry 99 (51), S. 17917 - 17925 (1995)

Loos, H.; Ermler, U.; Sprenger, G. A.; Sahm, H.: Crystallization and preliminary x‐ray analysis of glucose‐fructose oxidoreductase from zymomonas mobilis. Protein Science 3 (12), S. 2447 - 2449 (1994)

Ermler, U.; Fritzsch, G.; Buchanan, S. K.; Michel, H.: Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 A resolution: cofactors and protein-cofactor interactions. Structure 2 (10), S. 925 - 936 (1994)

Ermler, U.; Michel, H.; Schiffer, M.: Structure and Function of the Photosynthetic Reaction Center from Rhodobacter sphaeroides. Journal of Bioenergetics and Biomembranes 26 (1), S. 5 - 15 (1994)

Buchanan, S. K.; Fritzsch, G.; Ermler, U.; Michel, H.: New Crystal Form of the Photosynthetic Reaction Centre from Rhodobacter sphaeroides of Improved Diffraction Quality. Journal of Molecular Biology (London) 230 (4), S. 1311 - 1314 (1993)

Lindqvist, Y.; Schneider, G.; Ermler, U.; Sundström, M.: Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 Å resolution. EMBO Journal 11 (7), S. 2373 - 2379 (1992)

Ermler, U.; Ghisla, S.; Massey, V.; Schulz, G. E.: Structural, spectroscopic and catalytic activity studies on glutathione reductase reconstituted with FAD analogues. European Journal of Biochemistry 199 (1), S. 133 - 138 (1991)

Ermler, U.; Schulz, G. E.: The three‐dimensional structure of glutathione reductase from Escherichia coli at 3.0 Å resolution. Proteins: Structure, Function, and Bioinformatics 9 (3), S. 174 - 179 (1991)

Scheller, S.; Ermler, U.; Shima, S.: Catabolic Pathways and Enzymes Involved in Anaerobic Methane Oxidation. In: Handbook of Hydrocarbon and Lipid Microbiology, S. 1 - 29. Springer International Publishing AG 2017, 6330 Cham Switzerland (2017)

Shima, S.; Fujishiro, T.; Ermler, U.: Structure and function of [Fe]-hydrogenase and biosynthesis of the FeGP cofactor. In: Biohydrogen, S. 127 - 144 (Hg. Rögner, M.). Walter de Gruyter GmbH, Berlin (2015)

Parey, K.; Schiffer, A.; Steuber, J.; Fritz, G.; Ermler, U.; Kroneck, P. M. H.: Dissimilatory Sulfite Reductase. In: Handbook of Metalloproteins, Volume 4, 3, S. 103 - 110 (Hg. Messerschmidt, A.). John Wiley & Sons Ltd, The Atrium, Chichester, West Sussex, United Kingdom (2011)

Schiffer, A.; Fritz, G.; Büchert, T.; Herrmanns, K.; Steuber, J.; Ermler, U.; Kroneck, P. M. H.: Dissimilatory adenosine-5’-phosphosulfate reductase. In: Handbook of Metalloproteins, Volume 4, 4, S. 183 - 194 (Hg. Messerschmidt, A.). John Wiley & Sons Ltd, The Atrium, Chichester, West Sussex, United Kingdom (2011)

Fritzsch, G.; Ermler, U.; Merckel, M. C.; Michel, H.: Crystallization and Structure of the Photosynthetic Reaction Centres from Rhodobacter sphaeroides - wild type and mutants. In: The Reaction Center of Photosynthetic Bacteria, S. 3 - 13 (Hg. Michel-Beyerle, M.-E.). Springer, Berlin, Heidelberg (1996)

Lancaster, C. R. D.; Ermler, U.; Michel, H.: The Structures of Photosynthetic Reaction Centers from Purple Bacteria as Revealed by X-Ray Crystallography. In: Advances in Photosynthesis and Respiration, Bd. 2, S. 503 - 526 (Hg. Blankenship , R. E.; Madigan , M. T.; Bauer, C. E.). Kluwer Academic Publishers 1995, Springer, Dordrecht (1995)

Shima , S.; Thauer, R. K.; Ermler, U.: Hyperthermophilic and salt-dependent formyltransferase from Methanopyrus kandleri. Thermophiles 2003, University of Exeter, UK, 15. September 2003 - 19. September 2003. Biochemical Society Transactions 32 (2), 2 Aufl., S. 269 - 272 (2004)

Ermler, U.; Fritzsch, G.; Buchanan, S. K.; Michel, H.: Structure-function relationship in the photosynthetic reaction centre from the purple bacteria as revealed by X-ray crystallography analysis of a new trigonal crystal form of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 Å resolution. In: Research in Photosythesis, Bd. 1, S. 341 - 347 (Hg. Murata, N.). Proceedings of the IXth International Congress on Photosynthesis, Nagoya, Japan, 30. August 1992 - 04. September 1992. Springer Science & Business Media, Kluwer Academic Publishers (1992)

Schulz, G. E.; Ermler, U.: Structural changes on binding FAD and FAD-analogous and on site-directed mutagenesis of glutathione reductase. In: Flavins and Flavoproteins 1990, S. 505 - 512 (Hg. Curti, B.). Proceedings of the Tenth International Symposium on Flavins and Flavoproteins, Como, Italy, 15. Juli 1990 - 20. Juli 1990. Walter de Gruyter, Berlin, New York (1991)

Massey, V.; Ghislat, S.; Ermler, U.; Schulz, G. E.: Studies on the active site of human erythrocyte glutathione reductase using 6-SCN-FAD and 6-mercapto - FAD. In: Flavins and Flavoproteins, S. 79 - 84 (Hg. Edmondson, D. E.; McCormick, D. B.). Proceedings of the Ninth International Symposium on Flavins and Flavoproteins, Atlanta, Georgia, USA, 07. Juni 1987 - 12. Juni 1987. Walter de Gruyter & Co.,, Berlin, New York (1987)

Ermler, U.: Strukturuntersuchungen an Enzymen des methanogenen Stoffwechselweges. Habilitation, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2002)