Dr.-Ing. Beata Turonova

Project Group Leader

Molecular Sociology
+49 69 6303 3516

Main Focus

My aim is to facilitate in situ structural analysis by developing novel algorithms for cryo electron tomography and subtomogram averaging. Our method development focuses on improving tomogram quality and integrating contextual information into subtomogram averaging routines. The goal is to allow for reliable and objective analysis of tomograms as well as macromolecular complexes.

Curriculum Vitae

2005-2008: Bachelor studies in Computer Science, Charles University, Prague
2009-2011: Master studies in Visual Computing, Saarland University, Saarbrücken
2012-2016: PhD studies in Computer Graphics, Saarland University, Saarbrücken
2016-2017: Postdoctoral Fellow in John Briggs' laboratory (Structural and Computational Biology Department), EMBL, Heidelberg
2017-2020: Postdoctoral Fellow in Martin Beck's laboratory (Structural and Computational Biology Department), EMBL, Heidelberg
2020-present: Project group leader at the department of Molecular Sociology, Max-Planck Institute of Biophysics, Frankfurt am Main

Beata Turoňová Publications

Journal Article (7)

Journal Article

Khusainov, I.; Romanov, N.; Goemans, C.; Turoňová, B.; Zimmerli, C. E.; Welsch, S.; Langer, J. D.; Typas, A.; Beck, M.: Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction. Nature Communications 15, 4783 (2024)

MPG.PuRe

DOI

Full

Journal Article

Cruz-León, S.; Majtner, T.; Hoffmann, P. C.; Kreysing, J. P.; Kehl, S.; Tuijtel, M.; Schaefer, S. L.; Geißler, K.; Beck, M.; Turoňová, B. et al.; Hummer, G.: High-confidence 3D template matching for cryo-electron tomography. Nature Communications 15, 3992 (2024)

MPG.PuRe

DOI

Full

Journal Article

Tuijtel, M.; Cruz-León, S.; Kreysing, J. P.; Welsch, S.; Hummer, G.; Beck, M.; Turoňová, B.: Thinner is not always better: Optimizing cryo-lamellae for subtomogram averaging. Science Advances 10 (17), eadk6285 (2024)

MPG.PuRe

DOI

Full

Journal Article

Liu, J.; Corroyer-Dulmont, S.; Pražák, V.; Khusainov, I.; Bahrami, K.; Welsch, S.; Vasishtan, D.; Obarska-Kosińska, A.; Thorkelsson, S. R.; Grünewald, K. et al.; Quemin, E. R. J.; Turoňová, B.; Locker, J. K.: The palisade layer of the poxvirus core is composed of flexible A10 trimers. Nature Structural & Molecular Biology (2024)

MPG.PuRe

DOI

Full

Journal Article

Xing, H.; Taniguchi, R.; Khusainov, I.; Kreysing, J. P.; Welsch, S.; Turoňová, B.; Beck, M.: Translation dynamics in human cells visualized at high resolution reveal cancer drug action. Science 381 (6653), pp. 70 - 75 (2023)

MPG.PuRe

DOI

Full

Journal Article

Mosalaganti, S.; Obarska-Kosinska, A.; Siggel, M.; Taniguchi, R.; Turoňová, B.; Zimmerli, C. E.; Buczak, K.; Schmidt, F. H.; Margiotta, E.; Mackmull, M.-T. et al.; Hagen, W. J. H.; Hummer, G.; Kosinski, J.; Beck, M.: AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science 376 (6598), eabm9506 (2022)

MPG.PuRe

DOI

Full

Journal Article

Turoňová, B.; Sikora, M.; Schürmann, C.; Hagen, W. J. H.; Welsch, S.; Blanc, F. E. C.; von Bülow, S.; Gecht, M.; Bagola, K.; Hörner, C. et al.; van Zandbergen, G.; Landry, J.; de Azevedo, N. T. D.; Mosalaganti, S.; Schwarz, A.; Covino, R.; Mühlebach, M. D.; Hummer, G.; Krijnse Locker, J.; Beck, M.: In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges. Science 370 (6513), pp. 203 - 208 (2020)

MPG.PuRe

DOI

Full

Book Chapter (1)

Book Chapter

Turoňová, B.; Wan, W.: Subtomogram Averaging. In: Cryo-Electron Tomography (Eds. Förster, F.; Briegel, A.). Springer (2024)

MPG.PuRe

DOI