Publikationen von Ana J. García-Sáez

Subburaj, Y.; Ros, U.; Hermann, E.; Tong, R.; García-Sáez, A. J.: Toxicity of an α-pore-forming toxin depends on the assembly mechanism on the target membrane as revealed by single molecule imaging. Journal of Biological Chemistry 290 (8), S. 4856 - 4865 (2015)

Bleicken, S.; Jeschke, G.; Stegmueller, C.; Salvador-Gallego, R.; García-Sáez, A. J.; Bordignon, E.: Structural model of active Bax at the membrane. Molecular Cell 56 (4), S. 496 - 505 (2014)

Ugarte-Uribe, B.; Müller, H.-M.; Otsuki, M.; Nickel, W.; García-Sáez, A. J.: Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane division. Journal of Biological Chemistry 289 (44), S. 30645 - 30656 (2014)

Cosentino, K.; García-Sáez, A. J.: Mitochondrial alterations in apoptosis. Chemistry and Physics of Lipids 181, S. 62 - 75 (2014)

Hermann, E.; Bleicken, S.; García-Sáez, A. J.; Subburaj, Y. D.: Automated analysis of Giant Unilamellar Vesicles using Circular Hough Transformation. Bioinformatics 30 (12), S. 1747 - 1754 (2014)

Ugarte-Uribe, B.; García-Sáez, A. J.: Membranes in motion: mitochondrial dynamics and their role in apoptosis. Biological Chemistry 395 (3), S. 297 - 311 (2014)

Unsay, J. D.; Consentino, K.; Subburaj, Y.; García-Sáez, A. J.: Cardiolipin Effects on Membrane Structure and Dynamics. Langmuir 29 (51), S. 15878 - 15887 (2013)

Bleicken, S.; Landeta, O.; Landajuela, A.; Basanez, G.; Garcia-Saez, A. J.: Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size. Journal of Biological Chemistry 288 (46), S. 33241 - 33252 (2013)

Jalmar, O.; Francois-Moutal, L.; García-Sáez, A. J.; Perry, M.; Granjon, T.; Gonzalvez, F.; Gottlieb, E.; Ayala-Sanmartin, J.; Klosgen, B.; Schwille, P. et al.; Petit, P. X.: Caspase-8 Binding to Cardiolipin in Giant Unilamellar Vesicles Provides a Functional Docking Platform for Bid. PLOS ONE 8 (2), e55250 (2013)

Bleicken, S.; Wagner, C.; García-Sáez, A. J.: Mechanistic differences in the membrane activity of Bax and Bcl-xL correlate with their opposing roles in apoptosis. Biophysical Journal 104 (2), S. 421 - 431 (2013)

Steringer, J. P.; Bleicken, S.; Andreas, H.; Zacherl, S.; Laussmann, M.; Temmerman, K.; Contreras, F. X.; Bharat, T. A. M.; Lechner, J.; Müller, H.-M. et al.; Briggs, J. A. G.; García-Sáez, A. J.; Nickel, W.: Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P-2)-dependent Oligomerization of Fibroblast Growth Factor 2 (FGF2) Triggers the Formation of a Lipidic Membrane Pore Implicated in Unconventional Secretion. Journal of Biological Chemistry 287 (33), S. 27659 - 27669 (2012)

Bleicken, S.; García Sáez, A.; Conte, E.; Bordignon, E.: Dynamic interaction of cBid with detergents, liposomes and mitochondria. PLOS ONE 7 (4), e35910 (2012)

Bleicken, S.; Garcia-Saez, A. J.; Conte, E.; Bordignon, E.: Dynamic interaction of cBid with detergents, liposomes and mitochondria. PLOS ONE 7 (4), e35910 (2012)

Leprivier, G.; Rufini, A.; García-Sáez, A. J.; Borner, C.; Rotblat, B.: 7th Tuscany Retreat on Cancer Research: Genetic profiling, resistance mechanism and novel treatment concepts in cancer. Cell Death and Differentiation 19, S. 546 - 548 (2012)

Bleicken, S.; Otsuki, M.; García-Sáez, A. J.: Quantification of protein-protein interactions within membranes by fluorescence correlation spectroscopy. Current Protein & Peptide Science 12 (8), S. 691 - 698 (2011)

García-Sáez, A. J.; Buschhorn, S. B.; Keller, H.; Anderluh, G.; Simons, K.; Schwille, P.: Oligomerization and pore formation by equinatoxin II inhibit endocytosis and lead to plasma membrane reorganization. Journal of Biological Chemistry 286 (43), S. 37768 - 37777 (2011)

Apellániz, B.; García-Sáez, A. J.; Nir, S.; Nieva, J. L.: Destabilization exerted by peptides derived from the membrane-proximal external region of HIV-1 gp41 in lipid vesicles supporting fluid phase coexistence. Biochimica et Biophysica Acta: BBA 1808 (7), S. 1797 - 1805 (2011)

Jalmar, O.; García-Sáez, A. J.; Berland, L.; Gonzalvez, F.; Petit, P. X.: Giant unilamellar vesicles (GUVs) as a new tool for analysis of caspase-8/Bid-FL complex binding to cardiolipin and its functional activity. Cell Death and Disease 1, e103 (2010)

Apellániz, B.; Nieva, J. L.; Schwille, P.; García-Sáez, A. J.: All-or-none versus graded: single-vesicle analysis reveals lipid composition effects on membrane permeabilization. Biophysical Journal 99 (11), S. 3619 - 3628 (2010)

Fuertes, G.; García-Sáez, A. J.; Esteban-Martín, S.; Giménez, D.; Sánchez-Muñoz, O. L.; Schwille, P.; Salgado, J.: Pores formed by Baxα5 relax to a smaller size and keep at equilibrium. Biophysical Journal 99 (9), S. 2917 - 2925 (2010)

Klose, C.; Ejsing, C. S.; García-Sáez, A. J.; Kaiser, H.-J.; Sampaio, J. L.; Surma, M. A.; Shevchenko, A.; Schwille, P.; Simons, K.: Yeast lipids can phase-separate into micrometer-scale membrane domains. Journal of Biological Chemistry 285 (39), S. 30224 - 30232 (2010)

García-Sáez, A. J.; Schwille, P.: Stability of lipid domains. FEBS Letters 584 (9), S. 1653 - 1658 (2010)

Apellaniz, B.; García-Sáez, A. J.; Huarte, N.; Kunert, R.; Vorauer-Uhl, K.; Katinger, H.; Schwille, P.; Nieva, J. L.: Confocal microscopy of giant vesicles supports the absence of HIV-1 neutralizing 2F5 antibody reactivity to plasma membrane phospholipids. FEBS Letters 584 (8), S. 1591 - 1596 (2010)

García-Sáez, A. J.; Schwille, P.: Surface analysis of membrane dynamics. Biochimica et Biophysica Acta: BBA 1798 (4), S. 766 - 776 (2010)

García-Sáez, A. J.; Ries, J.; Orzáez, M.; Pérez-Payà, E.; Schwille, P.: Membrane promotes tBID interaction with BCL(XL). Nature Structural & Molecular Biology 16 (11), S. 1178 - 1185 (2009)

Ivashyna, O.; García-Sáez, A. J.; Ries, J.; Christenson, E. T.; Schwille, P.; Schlesinger, P. H.: Detergent-activated BAX protein is a monomer. Journal of Biological Chemistry 284 (36), S. 23935 - 23946 (2009)

García-Sáez, A. J.; Schwille, P.: Fluorescence correlation spectroscopy for the study of membrane dynamics and protein/lipid interactions. Methods 46 (2), S. 116 - 122 (2008)

Schön, P.; García-Sáez, A. J.; Malovrh, P.; Bacia, K.; Anderluh, G.; Schwille, P.: Equinatoxin II permeabilizing activity depends on the presence of sphingomyelin and lipid phase coexistence. Biophysical Journal 95 (2), S. 691 - 698 (2008)

García-Sáez, A. J.; Chiantia, S.; Schwille, P.: Effect of line tension on the lateral organization of lipid membranes. Journal of Biological Chemistry 282 (46), S. 33537 - 33544 (2007)

García-Sáez, A. J.; Schwille, P.: Single molecule techniques for the study of membrane proteins. Applied Microbiology and Biotechnology 76 (2), S. 257 - 266 (2007)

García-Sáez, A. J.; Chiantia, S.; Salgado, J.; Schwille, P.: Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM. Biophysical Journal 93 (1), S. 103 - 112 (2007)

García-Sáez, A. J.; Coraiola, M.; Serra, M. D.; Mingarro, I.; Müller, P.; Salgado, J.: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores. The FEBS Journal 273 (5), S. 971 - 981 (2006)

García-Sáez, A. J.; García-Sáez, A. J.; Coraiola, M.; Dalla Serra, M.; Mingarro, I.; Menestrina, G.; Salgado, J.: Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins. Biophysical Journal 88 (6), S. 3976 - 3990 (2005)

Garcia-Saez, A. J.; Mingarro, I.; Pérez-Payá, E.; Salgado, J.: Membrane-insertion fragments of Bcl-xL, Bax, and Bid. Biochemistry 43 (34), S. 10930 - 10943 (2004)

Salgado, J.; García-Sáez, A. J.; Malet, G.; Mingarro, I.; Pérez-Payá, E.: Peptides in apoptosis research. Journal of Peptide Science 8 (10), S. 543 - 560 (2002)

Iglič, A.; Rappolt, M.; García-Sáez, A. J. (Hg.): Advances in Biomembranes and Lipid Self-Assembly - Vol. 34. Elsevier (2021), 206 S.

Rappolt, M.; García-Sáez, A. J.: Advances in Biomembranes and Lipid Self-Assembly - Vol. 31. Elsevier (2020), 214 S.

Iglič, A.; Rappolt, M.; García-Sáez, A. J. (Hg.): Advances in Biomembranes and Lipid Self-Assembly - Vol. 27. Elsevier (2018), 250 S.

Rappolt, M.; García-Sáez, A. J.: Advances in Biomembranes and Lipid Self-Assembly - Vol. 28. Elsevier (2018), 198 S.

Rappolt, M.; García-Sáez, A. J.: Advances in Biomembranes and Lipid Self-Assembly - Vol. 29. Elsevier (2018), 258 S.

Iglič, A.; García-Sáez, A. J. (Hg.): Advances in Biomembranes and Lipid Self-Assembly - Vol. 25. Elsevier (2017), 186 S.

Rappolt, M.; García-Sáez, A. J.: Advances in Biomembranes and Lipid Self-Assembly - Vol. 26. Elsevier (2017), 199 S.

Jenner, A.; Garcia-Saez, A. J.: The regulation of the apoptotic pore - An immunological tightrope walk. In: Advances in Immunology, Bd. 162, S. 59 - 108 (Hg. Alt, F. W.; Murphy, K. M.). Elsevier (2024)

Dellmann, T.; Shalaby, R.; Garcia-Saez, A. J.: Super-resolution microscopy methods to study membrane pores in situ. In: Methods in Enzymology, Bd. 700, S. 161 - 187 (Hg. Baumgart, T.; Deserno, M.). Academic Press (2024)

Dellmann, T.; Kostina, A.; García-Sáez, A. J.: Single-Molecule Microscopy Methods to Study Mitochondrial Processes. In: Fluorescence Spectroscopy and Microscopy in Biology, Bd. 20, S. 337 - 353 (Hg. Šachl, R.; Amaro, M.). Springer, Cham (2023)

Röck, B. F.; Shalaby, R.; García-Sáez, A. J.: Pyroptosis Induction and Visualization at the Single-Cell Level Using Optogenetics. In: Springer Protocols - Methods in Molecular Biology: NLR Proteins, Bd. 2696, S. 135 - 147 (Hg. Pelegrín, P.; Di Virgilio, F.). Springer, New York (2023)

Flores-Romero, H.; García-Sáez, A. J.: MERLIN: A BRET-Based Proximity Biosensor for Studying Mitochondria-ER Contact Sites. In: Springer Protocols - Methods in Molecular Biology: Bioluminescence, Bd. 2525, S. 197 - 205 (Hg. Kim, S.-B.). Springer US, New York, NY (2022)

Flores-Romero, H.; Ros, U.; García-Sáez, A. J.: Chapter six: A lipid perspective on regulated cell death. In: International Review of Cell and Molecular Biology, Bd. 351, S. 197 - 236 (Hg. Spetz, J. K. E.; Galluzzi, L.) (2020)

Murad, F.; Garcia-Saez, A. J.: Quantification of the Interactions Between BCL-2 Proteins by Fluorescence Correlation Spectroscopy. In: Springer Protocola - Methods in Molecular Biology: BCL-2 Family Proteins, Bd. 1877, S. 337 - 350 (Hg. Gavathiotis, E.). Humana Press (2019)

Ugarte-Uribe, B.; Das, K. K.; García-Sáez, A. J.: Lipid and protein mobility in giant unilamellar vesicles. In: The Giant Vesicle Book. CRC Press (2019)

Ugarte-Uribe, B.; García-Sáez, A. J.; Claessens, M. M. A. E.: Membrane permeability measurements. In: The Giant Vesicle Book. CRC Press (2019)

Unsay, J. D.; García-Sáez, A. J.: AFM to Study Pore-Forming Proteins. In: Springer Protocols - Methods in Molecular Biology: Atomic Force Microscopy, Bd. 1886, S. 191 - 202 (Hg. Santos, N. C.; Carvalho, F. A.) (2019)

Zehnle, P. M. A.; Kollek, M.; Murad, F.; Fischer, N.; Kunze, M.; García-Sáez, A. J.; Erlacher, M.: Combination of ex vivo expansion with apoptosis inhibition in donor hematopoietic stem cells. In: Klinische Pädiatrie: 30. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch-onkologische Forschung Wilsede, Lüneburger Heide, 07.06 – 10.06.2017, Bd. 3, S. 182 - 195. Thieme, Stuttgart (2017)

Das, K. K.; Unsay, J. D.; García-Sáez, A. J.: Microscopy of Model Membranes: Understanding How Bcl-2 Proteins Mediate Apoptosis. In: Advances in Planar Lipid Bilayers and Liposomes, Bd. 21, S. 63 - 97 (Hg. Iglic, A.; Kulkarni , C. V.; Rappolt, M.). Elsevier, Amsterdam (2015)

Hermann, E.; Ries, J.; García-Sáez, A. J.: Scanning Fluorescence Correlation Spectroscopy on Biomembranes. In: Methods in Membrane Lipids, Bd. 1232, S. 181 - 197 (Hg. Owen, D. M.). Humana Press (2015)

Bleicken, S.; García-Sáez, A. J.: New Biophysical Methods to Study the Membrane Activity of Bcl-2 Proteins. In: Cancer Genomics and Proteomics. Methods and Protocols, Bd. 1176, S. 191 - 207 (Hg. Wajapeyee, N.). Humana Press, New York (2014)

Subburaj, Y.; Gallego, R. S.; García-Sáez, A. J.: Membrane Dynamics: Fluorescence Spectroscopy. In: Encyclopedia of Analytical Chemistry. Wiley (2013)

Unsay, J. D.; García-Sáez, A. J.: Scanning fluorescence correlation spectroscopy in model membrane systems. In: Springer Protocols - Methods in Molecular Biology: Membrane Biogenesis: Methods and Protocols, Bd. 1033, S. 185 - 205 (Hg. Rapaport, D.; Herrmann, J. M.). Humana Press (2013)

Zelman-Femiak, M.; Subburaj, Y.; García-Sáez, A. J.: Fluorescence correlation spectroscopy to study membrane organization and interactions. In: Springer Series of Fluorescence, Bd. 13, S. 241 - 269 (Hg. Duportail, G.; Mély, Y.) (2013)

Fuertes, G.; Giménez, D.; Esteban-Martín, S.; García-Sáez, A. J.; Sánchez, O.; Salgado, J.: Role of Membrane Lipids for the Activity of Pore Forming Peptides and Proteins. In: Proteins Membrane Binding and Pore Formation, Bd. 677, S. 31 - 55 (Hg. Anderluh, G.; Lakey, J.). Springer, New York, NY (2010)

García-Sáez, A. J.; Carrer, D. C.; Schwille, P.: Fluorescence correlation spectroscopy for the study of membrane dynamics and organization in giant unilamellar vesicles. In: Springer Protocols - Methods in Molecular Biology :Liposomes - Methods and Protocols; Volume 2: Biological Memrane Models, Bd. 606, S. 493 - 508 (Hg. Weissig, V.). Humana Press (2010)

García-Sáez, A. J.; Fuertes, G.; Suckale, J.; Salgado, J.: Permeabilization of the outer mitochondrial membrane by Bcl-2 proteins. In: Advances in Experimental Medicin and Biology, Bd. 677, S. 91 - 105 (Hg. Anderluh, G.; Lakey, J.). Academic Press (2010)