Publikationen von Deryck J. Mills

Zeitschriftenartikel (45)

2022
Zeitschriftenartikel
Lee, Y.; Wiriyasermkul, P.; Kongpracha, P.; Moriyama, S.; Mills, D. J.; Kühlbrandt, W.; Nagamori, S.: Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria. Nature Communications 13, 2708 (2022)
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2021
Zeitschriftenartikel
Parey, K.; Lasham, J.; Mills, D. J.; Djurabekova, A.; Haapanen, O.; Yoga, E. G.; Xie, H.; Kühlbrandt, W.; Sharma, V.; Vonck, J. et al.; Zickermann, V.: High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances 7 (46), eabj3221 (2021)
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Zeitschriftenartikel
Heit, S.; Geurts, M. M. G.; Murphy, B. J.; Corey, R. A.; Mills, D. J.; Kühlbrandt, W.; Bublitz, M.: Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances 7 (46), eabj5255 (2021)
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Zeitschriftenartikel
Wieferig, J.-P.; Mills, D. J.; Kühlbrandt, W.: Devitrification reduces beam-induced movement in cryo-EM. IUCrJ 8 (Pt 2), S. 186 - 194 (2021)
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Zeitschriftenartikel
Cunha, E. S.; Chen, X.; Sanz-Gaitero, M.; Mills, D. J.; Luecke, H.: Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution. Nature Communications 12 (1), 230 (2021)
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Zeitschriftenartikel
Mills, D. J.: Setting up and operating a cryo-EM laboratory. Quarterly Reviews of Biophysics 54, e2 (2021)
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2020
Zeitschriftenartikel
Ebenhoch, R.; Prinz, S.; Kaltwasser, S.; Mills, D. J.; Meinecke, R.; Rübbelke, M.; Reinert, D.; Bauer, M.; Weixler, L.; Zeeb, M. et al.; Vonck, J.; Nar, H.: A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. Proceedings of the National Academy of Sciences of the United States of America 117 (50), S. 31838 - 31849 (2020)
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Zeitschriftenartikel
Wu, D.; Grund, T. N.; Welsch, S.; Mills, D.; Michel, M.; Safarian, S.; Michel, H.: Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proceedings of the National Academy of Sciences of the United States of America 117 (35), 202008111, S. 21281 - 21287 (2020)
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Zeitschriftenartikel
Tascón, I.; Sousa, J. S.; Corey, R. A.; Mills, D. J.; Griwatz, D.; Aumüller, N.; Mikusevic, V.; Stansfeld, P. J.; Vonck, J.; Hänelt, I.: Structural basis of proton-coupled potassium transport in the KUP family. Nature Communications 11, 626 (2020)
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2019
Zeitschriftenartikel
Brünle, S.; Eisinger, M. L.; Poppe, J.; Mills, D. J.; Langer, J. D.; Vonck, J.; Ermler, U.: Molybdate pumping into the molybdenum storage protein via an ATP-powered piercing mechanism. Proceedings of the National Academy of Sciences of the United States of America 52 (116), S. 26497 - 26504 (2019)
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Zeitschriftenartikel
Parey, K.; Haapanen, O.; Sharma, V.; Köfeler, H.; Züllig, T.; Prinz, S.; Siegmund, K.; Wittig, I.; Mills, D.; Vonck, J. et al.; Kühlbrandt, W.; Zickermann, V.: High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Science Advances 5 (12), S. eaax9484 (2019)
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Zeitschriftenartikel
Pfeil-Gardiner, O.; Mills, D. J.; Vonck, J.; Kühlbrandt, W.: A comparative study of single-particle cryo-EM with liquid-nitrogen and liquid-helium cooling. IUCrJ 6, S. 1099 - 1105 (2019)
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Zeitschriftenartikel
Safarian, S.; Hahn, A.; Mills, D.; Radloff, M.; Eisinger, M. L.; Nikolaev, A.; Meier-Credo, J.; Melin, F.; Miyoshi, H.; Gennis, R.B. et al.; Sakamoto, J.; Langer, J. D.; Hellwig, P.; Kühlbrandt, W.; Michel, H.: Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 366 (6461), S. 100 - 104 (2019)
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Zeitschriftenartikel
Murphy, B. J.; Klusch, N.; Langer, J. D.; Mills, D.; Yildiz, Ö.; Kühlbrandt, W.: Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. Science 364 (6446), eaaw9128, S. 1155 (2019)
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2018
Zeitschriftenartikel
Parey, K.; Brandt, U.; Xie, H.; Mills, D. J.; Siegmund, K.; Vonck, J.; Kühlbrandt, W.; Zickermann, V.: Cryo-EM structure of respiratory complex I at work. eLife 7, e39213 (2018)
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Zeitschriftenartikel
Sousa, J. S.; Calisto, F.; Langer, J. D.; Mills, D. J.; Refojo, P. N.; Teixeira, M.; Kühlbrandt, W.; Vonck, J.; Pereira, M. M.: Structural basis for energy transduction by respiratory alternative complex III. Nature Communications 9, 1728 (2018)
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Zeitschriftenartikel
Hahn, A.; Vonck, J.; Mills, D. J.; Meier, T.; Kühlbrandt, W.: Structure, mechanism, and regulation of the chloroplast ATP synthase. Science 360 (6389), S. 1 - 10 (2018)
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2017
Zeitschriftenartikel
Klusch, N.; Murphy, B. J.; Mills, D.; Yildiy, Ö.; Kühlbrandt, W.: Structural basis of proton translocation and force generation in mitochondrial ATP synthase. eLife 6, e33274 (2017)
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Zeitschriftenartikel
Bausewein, T.; Mills, D. J.; Langer, J. D.; Nitschke, B.; Nussberger, S.; Kühlbrandt, W.: Cryo-EM Structure of the TOM Core Complex from Neurospora crassa. Cell 170 (4), S. 693 - 700 (2017)
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Zeitschriftenartikel
van Pee, K.; Neuhaus, A.; D'Imprima, E.; Mills, D. J.; Kühlbrandt, W.; Yildiz, Ö.: CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin. eLife 6, e23644 (2017)
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Zeitschriftenartikel
Diskowski, M.; Mehdipour, A. R.; Wunnicke, D.; Mills, D. J.; Mikusevic, V.; Bärland, N.; Hoffmann, J.; Morgner, N.; Steinhoff, H.-J.; Hummer, G.: Helical jackknives control the gates of the double-pore K+ uptake system KtrABs. eLife, S. 1 - 21 (2017)
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Zeitschriftenartikel
Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R.; Cramer, P.: Architecture of a transcribing-translating expressome. Science 356, S. 194 - 197 (2017)
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Zeitschriftenartikel
López-Alonso, J. P.; Kaminishi, T.; Kikuchi, T.; Hirata, Y.; Iturrioz, I.; Dhimole, N.; Schedlbauer, A.; Hase, Y.; Goto, S.; Kurita, D. et al.; Muto, A.; Zhou, S.; Naoe, C.; Mills, D. J.; Gil-Carton, D.; Takemoto, C.; Himeno, H.; Fucini, P.; Connell, S. R.: RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Research 45 (11), S. 6945 - 6959 (2017)
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Zeitschriftenartikel
Schulz, S.; Wilkes, M.; Mills, D. J.; Kühlbrandt, W.; Meier, T.: Molecular architecture of the N‐type ATPase rotor ring from Burkholderia pseudomallei. EMBO Reports 18 (6), S. 1 - 10 (2017)
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Zeitschriftenartikel
Vonck, J.; Mills, D. J.: Advances in high-resolution cryo-EM of oligomeric enzymes. Current Opinion in Structural Biology 46, S. 48 - 54 (2017)
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2016
Zeitschriftenartikel
Sousa, J. S.; Mills, D. J.; Vonck, J.; Kühlbrandt, W.: Functional asymmetry and electron flow in the bovine respirasome. eLife 5, e21290 (2016)
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Zeitschriftenartikel
Vonck, J.; Parcej, D. N.; Mills, D. J.: Structure of Alcohol Oxidase from Pichia pastoris by Cryo-Electron Microscopy. PLOS ONE 11 (7), e0159476 (2016)
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Zeitschriftenartikel
Chaudhury, P.; Neiner, T.; D'Imprima, E.; Banerjee, A.; Reindl, S.; Ghosh, A.; Arvai, A. S.; Mills, D. J.; van der Does, C.; Tainer, J. A. et al.; Vonck, J.; Albers, S.: The nucleotide-dependent interaction of FlaH and FlaI isessential for assembly and function of the archaellum motor. Molecular Microbiology 99 (4), S. 674 - 685 (2016)
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Zeitschriftenartikel
D'Imprima, E.; Mills, D. J.; Parey, K.; Brandt, U.; Kühlbrandt, W.; Zickermann, V.; Vonck, J.: Cryo-EM structure of respiratory complex I reveals a link to mitochondrial sulfur metabolism. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1857 (12), S. 1935 - 1942 (2016)
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Zeitschriftenartikel
Hahn, A.; Parey, K.; Bublitz, M.; Mills, D. J.; Zickermann, V.; Vonck, J.; Kühlbrandt, W.; Meier, T.: Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology. Molecular Cell 63, S. 1 - 12 (2016)
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2015
Zeitschriftenartikel
Allegretti, M.; Klusch, N.; Mills, D. J.; Vonck, J.; Kühlbrandt, W.; Davies, K. M.: Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase. Nature 521, S. 237 - 240 (2015)
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Zeitschriftenartikel
Jiko, C.; Davies, K. M.; Shinzawa-Itoh, K.; Tani, K.; Maeda, S.; Mills, D. J.; Tsukihara, T.; Fujiyoshi, Y.; Kühlbrandt, W.; Gerle, C.: Bovine F1F0 ATP synthase monomers bend the lipid bilayer in 2D membrane crystals. eLife 4, e06119 (2015)
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Zeitschriftenartikel
Fischer, M.; Rhinow, D.; Zhu, Z.; Mills, D. J.; Zhao, Z. K.; Vonck, J.; Grininger, M.: Cryo-EM structure of fatty acid synthase (FAS) from Rhodosporidium toruloides provides insights into the evolutionary development of fungal FAS. Protein Science 24 (6), S. 987 - 995 (2015)
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2014
Zeitschriftenartikel
Allegretti, M.; Mills, D. J.; McMullen, G.; Kühlbrandt, W.; Vonck, J.: Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector. eLife 3, e01963 (2014)
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Zeitschriftenartikel
Daum, B.; Quax, T. E. F.; Sachse, M.; Mills, D. J.; Reimann, J.; Yildiz, Ö.; Häder, S.; Saveanu, C.; Forterre, P.; Albers, S.-V. et al.; Kühlbrandt, W.; Prangishvili, D.: Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids. Proceedings of the National Academy of Sciences of the United States of America 111 (10), S. 3829 - 3834 (2014)
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Zeitschriftenartikel
Davies, K. M.; Daum, B.; Gold, V. A. M.; Mühleip, A. W.; Brandt, T.; Blum, T.; Mills, D. J.; Kühlbrandt, W.: Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography. Journal of Visualized Experiments (91 doi: 10.3791/51228), e51228 (2014)
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2013
Zeitschriftenartikel
Mills, D. J.; Vitt, S.; Strauss, M.; Shima, S.; Vonck, J.: De novo modeling of the F420-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy. eLife 2, e00218 (2013)
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Zeitschriftenartikel
Ciccarelli, L.; Connell, S. R.; Enderle, M.; Mills, D. J.; Vonck, J.; Grininger, M.: Structure and Conformational Variability of the Mycobacterium tuberculosis Fatty Acid Synthase Multienzyme Complex. Structure 21 (7), S. 1251 - 1257 (2013)
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2012
Zeitschriftenartikel
Banerjee, A.; Ghosh, A.; Mills, D. J.; Kahnt, J.; Vonck, J.; Albers, S.-V.: FlaX, A Unique Component of the Crenarchaeal Archaellum, Forms Oligomeric Ring-shaped Structures and Interacts with the Motor ATPase FlaI. The Journal of Biological Chemistry 287 (52), S. 43322 - 43330 (2012)
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Zeitschriftenartikel
Hizlan, D.; Robson, A.; Whitehouse, S.; Gold, V. A.; Vonck, J.; Mills, D.; Kühlbrandt, W.; Collinson, I.: Structure of the SecY Complex Unlocked by a Preprotein Mimic. Cell Reports 1 (1), S. 21 - 28 (2012)
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2011
Zeitschriftenartikel
Althoff, T.; Mills, D. J.; Popot, J.-L.; Kühlbrandt, W.: Arrangement of electron transport chain components in bovine mitochondrial supercomplex I1III2IV1. EMBO Journal 30, S. 4652 - 4664 (2011)
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2010
Zeitschriftenartikel
Gipson, P.; Mills, D. J.; Wouts, R.; Grininger, M.; Vonck, J.; Kühlbrandt, W.: Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America 107 (20), S. 9164 - 9169 (2010)
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2009
Zeitschriftenartikel
Kamal, M. M.; Mills, D.; Grzybeck, M.; Howard, J.: Measurement of the membrane curvature preference of phospholipids reveals only weak coupling between lipid shape and leaflet curvature. Proceedings of the National Academy of Sciences of the United States of America 106 (52), S. 22245 - 22250 (2009)
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2004
Zeitschriftenartikel
Schmidt-Krey, I.; Kanaoka, Y.; Mills, D. J.; Lam, B. K.; Irikura, D.; Haase, W.; Austen, K. F.; Kühlbrandt, W.: Human Leukotriene C4 Synthase at 4.5 Å Resolution in Projection. Structure 12, S. 2009 - 2014 (2004)
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2001
Zeitschriftenartikel
Behlau, M.; Mills, D. J.; Quader, H.; Kühlbrandt, W.; Vonck, J.: Projection structure of the monomeric porin OmpG at 6 å resolution. Journal of Molecular Biology (London) 305 (1), S. 71 - 77 (2001)
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Buchkapitel (1)

2013
Buchkapitel
Mills, D. J.; Vonck, J.: Choice and Maintenance of Equipment for Electron Crystallography. In: Electron Crystallography of Soluble and Membrane Proteins: Methods and Protocols, Bd. 995, S. 331 - 351 (Hg. Schmidt-Krey, I.; Cheng, Y.). Springer Science+Business Media New York 2013, Humana Totowa, NJ (2013)
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Konferenzband (2)

2018
Konferenzband
Cryo-EM structure of the alternative complex III from Rhodothermus marinus (Biochim. Biophys. Acta (BBA) - Bioenergetics, 1859). (2018), 1 S.
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Konferenzband
The cryo EM structure of respiratory complex I from Yarrowia lipolytica (Biochim. Biophys. Acta (BBA) - Bioenergetics, 1859). Budapest, Hungary (2018), 01 S.
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