Publications of Hartmut Michel
All genres
Journal Article (258)
2004
Journal Article
1701 (1-2), pp. 129 - 132 (2004)
Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily. Biochimica et Biophysica Acta-Proteins and Proteomics
Journal Article
279 (26), pp. 26922 - 26931 (2004)
The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase µ. The Journal of Biological Chemistry
Journal Article
271, pp. 1677 - 1689 (2004)
Comparative analysis of high-affinity ligand binding and G protein coupling of the human CXCR1 chemokine receptor and of a CXCR1-Gi2α fusion protein after heterologous production in baculovirus-infected insect cells. European Journal of Biochemistry
Journal Article
86 (4), pp. 1873 - 1889 (2004)
Dynamic Water Networks in Cytochrome c Oxidase from Paracoccus denitrificans Investigated by Molecular Dynamics Simulations. Biophysical Journal
Journal Article
6, pp. 1 - 15 (2004)
Spectral dynamics in the B800 band of LH2 from Rhodospirillum molischianum: a single-molecule study. New Journal of Physics
Journal Article
10 (1), pp. 37 - 50 (2004)
Production of the Human D2S Receptor in the Methylotrophic Yeast P. pastoris. Receptors and Channels 2003
Journal Article
42 (19), pp. 5632 - 5639 (2003)
Asymmetric binding of the high-affinity QH.- ubisemiquinone in quinol oxidase (bo3) from Escherichia coli studied by multifrequency electron paramagnetic resonance spectroscopy. Biochemistry
Journal Article
D59 (4), pp. 677 - 687 (2003)
1.3 Å X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen)
Journal Article
: Isolation, Characterization and Electron Microscopic Single Particle Analysis of the NADH:Ubiquinone Oxidoreductase (Complex I) from the Hyperthermophilic Eubacterium Aquifex aeolicus. Biochemistry 42 (10), pp. 3032 - 3039 (2003)
Journal Article
90 (1), 013004 (2003)
Single-molecule study of the Electronic Couplings in a Circular Array of Molecules: Light-Harvesting-2-Complex from Rhodospirillum Molischianum. Physical Review Letters
Journal Article
84 (1), pp. 440 - 449 (2003)
Low-intensity pump-probe measurements on the B800 band of Rhodospirillum molischianum. Biophysical Journal 2002
Journal Article
12 (4), pp. 503 - 508 (2002)
Crystallisation of membrane proteins mediated by antibody fragments [Review]. Current Opinion in Structural Biology
Journal Article
41 (29), pp. 9116 - 9125 (2002)
Vibrational modes of tyrosines in cytochrome c oxidase from Paracoccus denitrificans: FTIR and electrochemical studies on Tyr-D4-labeled and on Tyr280His and Tyr35Phe mutant enzymes. Biochemistry
Journal Article
417 (6884), pp. 99 - 102 (2002)
Reduction of cytochrome c oxidase by a second electron leads to proton translocation. Nature 2001
Journal Article
268 (20), pp. 5386 - 5396 (2001)
Analysis of a putative voltage-gated prokaryotic potassium channel. European Journal of Biochemistry
Journal Article
40 (14), pp. 4253 - 4260 (2001)
X-ray Structure Analyses of Photosynthetic Reaction Center Variants from Rhodobacter sphaeroides: Structural Changes Induced by Point Mutations at Position L209 Modulate Electron and Proton Transfer. Biochemistry
Journal Article
40 (4), pp. 1037 - 1043 (2001)
QH*- Ubisemiquinone Radical in the bo3-Type Ubiquinol Oxidase Studied by Pulsed Electron Paramagnetic Resonance and Hyperfine Sublevel Correlation Spectroscopy. Biochemistry
Journal Article
7 (6), pp. 453 - 469 (2001)
Solubilization and purification of the human ETB endothelin receptor produced by high-level fermentation in Pichia pastoris. Receptors and Channels 2000
Journal Article
275 (50), pp. 39364 - 39368 (2000)
Structural basis of the drastically increased initial electron transfer rate in the reaction center from a Rhodopseudomonas viridis mutant described at 2.00-A resolution. The Journal of Biological Chemistry
Journal Article
407, p. 285 - 285 (2000)
Allowing gene patents could be an expensive mistake for the US. Nature
Journal Article
8 (6), pp. 669 - 684 (2000)
Structure at 2.3 Å resolution of the cytochrome bc1 complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment. Structure
Journal Article
39 (23), pp. 6756 - 6762 (2000)
Tracing the D-Pathway in Reconstituted Site-Directed Mutants of Cytochrome c Oxidase from Paracoccus denitrificans. Biochemistry
Journal Article
95 (11), pp. 3467 - 3472 (2000)
Heavy and light chain primary structures control IgG3 nephritogenicity in an experimental model for cryocrystalglobulinemia. Blood
Journal Article
97 (9), pp. 4632 - 4636 (2000)
Single-electron reduction of the oxidized state is coupled to proton uptake via the K pathway in Paracoccus denitrificans cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
39 (13), pp. 3592 - 3602 (2000)
Uphill Electron Transfer in the Tetraheme Cytochrome Subunit of the Rhodopseudomonas viridis Photosynthetic Reaction Center: Evidence from Site-Directed Mutagenesis. Biochemistry
Journal Article
267 (5), pp. 1368 - 1381 (2000)
Structural investigations of the CuA centre of nitrous oxide reductase from Pseudomonas stutzeri by site-directed mutagenesis and X-ray absorption spectroscopy. European Journal of Biochemistry
Journal Article
271 (7), pp. 4734 - 4742 (2000)
The Monoclonal Antibody 1F6 Identifies a pH-dependent Conformational Change in the Hydrophilic NH2 Terminus of NhaA Na+/H+ Antiporter of Escherichia coli. The Journal of Biological Chemistry
Journal Article
77 (2-3), pp. 219 - 234 (2000)
Engineering of a proteolytically stable human β2-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells. Journal of Biotechnology
Journal Article
39 (6), pp. 1356 - 1363 (2000)
Functional Properties of the Heme Propionates in Cytochrome c Oxidase from Paracoccus denitrificans. Evidence from FTIR Difference Spectroscopy and Site-Directed Mutagenesis. Biochemistry
Journal Article
295 (3), pp. 667 - 678 (2000)
Structure of the soluble domain of cytochrome c552 from Paracoccus denitrificans in the oxidized and reduced states. Journal of Molecular Biology (London)
Journal Article
7 (2), pp. 93 - 107 (2000)
The human ET(B) endothelin receptor heterologously produced in the methylotrophic yeast Pichia pastoris shows high-affinity binding and induction of stacked membranes. Receptors and Channels 1999
Journal Article
274 (53), pp. 37974 - 37981 (1999)
Mutation of Arg-54 Strongly Influences Heme Composition and Rate and Directionality of Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase. The Journal of Biological Chemistry
Journal Article
463 (1-2), pp. 169 - 174 (1999)
Identification of a hydrogen bond in the Phe M197→Tyr mutant reaction center of the photosynthetic purple bacterium Rhodobacter sphaeroides by X-ray crystallography and FTIR spectroscopy. FEBS Letters
Journal Article
402 (6762), pp. 602 - 603 (1999)
Proton pumping by cytochrome c oxidase. Nature
Journal Article
402 (6760), pp. 377 - 385 (1999)
Structure of fumarate reductase from Wolinella succinogenes at 2.2 Å resolution. Nature
Journal Article
274 (47), pp. 33296-9 - 33299 (1999)
The cytochrome c oxidase from Paracoccus denitrificans does not change the metal center ligation upon reduction. The Journal of Biological Chemistry
Journal Article
38 (46), pp. 15129 - 15140 (1999)
Cytochrome c Oxidase: Catalytic Cycle and Mechanisms of Proton Pumping-A Discussion. Biochemistry
Journal Article
38 (40), pp. 13179 - 13187 (1999)
In Rhodobacter sphaeroides Reaction Centers, Mutation of Proline L209 to Aromatic Residues in the Vicinity of a Water Channel Alters the Dynamic Coupling between Electron and Proton Transfer Processes. Biochemistry
Journal Article
456 (3), pp. 365 - 369 (1999)
Mutations in the Ca2+ binding site of the Paracoccus denitrificans cytochrome c oxidase. FEBS Letters
Journal Article
38 (29), pp. 9179 - 9184 (1999)
Direct Evidence for a Tyrosine Radical in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide. Biochemistry
Journal Article
38 (23), pp. 7565 - 7571 (1999)
Time-Resolved FT-IR Studies on the CO Adduct of Paracoccus denitrificans Cytochrome c Oxidase: Comparison of the Fully Reduced and the Mixed Valence Form. Biochemistry
Journal Article
286 (3), pp. 883 - 898 (1999)
Refined Crystal Structures of Reaction Centres from Rhodopseudomonas viridis in Complexes with the Herbicide Atrazine and Two Chiral Atrazine Derivatives also Lead to a New Model of the Bound Carotenoid. Journal of Molecular Biology (London)
Journal Article
38 (6), pp. 1685 - 1694 (1999)
Electrochemical and Ultraviolet/Visible/Infrared Spectroscopic Analysis of Heme a and a3 Redox Reactions in the Cytochrome c Oxidase from Paracoccus denitrificans: Separation of Heme a and a3 Contributions and Assignment of Vibrational Modes. Biochemistry 1998
Journal Article
441 (1), pp. 53 - 58 (1998)
Production and characterization of monoclonal antibodies directed against native epitopes of NhaA, the Na+/H+ antiporter of Escherichia coli. FEBS Letters
Journal Article
1409 (2), pp. 107 - 112 (1998)
Electrochemically induced FT-IR difference spectra of the two- and four-subunit cytochrome c oxidase from Paracoccus denitrificans reveal identical conformational changes upon redox transitions. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
95 (22), pp. 12819 - 12824 (1998)
The mechanism of proton pumping by cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
37 (25), pp. 9001 - 9008 (1998)
The 18 kDa Cytochrome c553 from Heliobacterium gestii: Gene Sequence and Characterization of the Mature Protein. Biochemistry
Journal Article
18 (5), pp. 509 - 524 (1998)
Characterization of the Human Gonadotropin-Releasing Hormone Receptor Heterologously Produced Using the Baculovirus/Insect Cell and the Semliki Forest Virus Systems. Cellular and Molecular Neurobiology
Journal Article
434 (1-2), pp. 17 - 22 (1998)
Electrical current generation and proton pumping catalyzed by the ba3-type cytochrome c oxidase from Thermus thermophilus. FEBS Letters
Journal Article
180 (12), pp. 3227 - 3232 (1998)
Cloning, Sequencing, and Characterization of the recA Gene from Rhodopseudomonas viridis and Construction of a recA Strain. Journal of Bacteriology
Journal Article
18 (3), pp. 347 - 360 (1998)
Characterization of the Human Dopamine Transporter Heterologously Expressed in BHK-21 Cells. Cellular and Molecular Biology
Journal Article
37 (20), pp. 7390 - 7399 (1998)
Involvement of Glutamic Acid 278 in the Redox Reaction of the Cytochrome c Oxidase from Paracoccus denitrificans Investigated by FTIR Spectroscopy. Biochemistry
Journal Article
37 (20), pp. 7400 - 7406 (1998)
Redox dependent changes at the heme propionates in cytochrome c oxidase from Paracoccus denitrificans: direct evidence from FTIR difference spectroscopy in combination with heme propionate 13C labeling. Biochemistry
Journal Article
330 (3), pp. 1137 - 1147 (1998)
Comparative biochemical and pharmacological characterization of the mouse 5HT5A 5-hydroxytryptamine receptor and the human beta2-adrenergic receptor produced in the methylotrophic yeast Pichia pastoris. Biochemical Journal
Journal Article
55, pp. 127 - 132 (1998)
Water clusters in the reaction centre of Rhodobacter sphaeroides. Photosynthesis Research
Journal Article
74 (2), pp. 708 - 721 (1998)
The Coupling of Electron Transfer and Proton Translocation: Electrostatic Calculations on Paracoccus denitrificans Cytochrome c Oxidase. Biophysical Journal
Journal Article
30 (1), pp. 81 - 87 (1998)
The Role of Electrostatic Interactions for Cytochrome c Oxidase Function. Journal of Bioenergetics and Biomembranes 1997
Journal Article
5 (10), pp. 1339 - 1359 (1997)
The coupling of light-induced electron transfer and proton uptake as derived from crystal structures of reaction centres from Rhodopseudomonas viridis modified at the binding site of the secondary quinone, QB. Structure
Journal Article
7 (5), pp. 697 - 701 (1997)
Crystallization of membrane proteins. Current Opinion in Structural Biology
Journal Article
94 (20), pp. 10547 - 10553 (1997)
Structure at 2.7 Å resolution of the Paracoccus denitrificans two subunit cytochrome c oxidase complexed with an antibody Fv fragment. Proceedings of the National Academy of Sciences of the United States of America 1996
Journal Article
26 (1), pp. 118 - 120 (1996)
Crystallization and preliminary X‐ray diffraction studies of formylmethanofuran: Tetrahydromethanopterin formyltransferase from Methanopyrus kandleri. Proteins: Structure, Function, and Bioinformatics
Journal Article
6 (4), pp. 460 - 466 (1996)
Cytochrome c oxidase. Current Opinion in Structural Biology
Journal Article
1275 (3), pp. 145 - 150 (1996)
Molecular cloning, DNA sequence and transcriptional analysis of the Rhodospirillum molischianum B800/850 light-harvesting genes. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
1275 (1-2), pp. 1 - 4 (1996)
Channelling of dioxygen into the respiratory enzyme. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
70 (6), pp. 2469 - 2492 (1996)
Calculated coupling of electron and proton transfer in the photosynthetic reaction center of Rhodopseudomonas viridis. Biophysical Journal
Journal Article
4 (5), pp. 567 - 579 (1996)
Structure of a water soluble fragment of the ‘Rieske’ iron-sulfur protein of the bovine heart mitochondrial cytochrome bc1 complex determined by MAD phasing at 1.5 Å resolution. Structure
Journal Article
4 (5), pp. 581 - 597 (1996)
The crystal structure of the light-harvesting complex II (B800-850) from Rhodospirillum molischianum. Structure
Journal Article
48, pp. 65 - 74 (1996)
Three-dimensional structures of photosynthetic reaction centers. Photosynthesis Research
Journal Article
24 (10), pp. 1979 - 1980 (1996)
Improved Cloning of Antibody Variable Regions From Hybridomas by an Antisense-Directed RNase H Digestion of the P3-X63-Ag8.653 Derived Pseudogene mRNA. Nucleic Acids Research (London)
Journal Article
385 (1-2), pp. 53 - 57 (1996)
Carboxyl group protonation upon reduction of the Paracoccus denitrificans cytochrome c oxidase: direct evidence by FTIR spectroscopy. FEBS Letters
Journal Article
31, pp. 183 - 188 (1996)
On the role of the N-terminus of the extrinsic 33 kDa protein of Photosystem II. Plant Molecular Biology
Journal Article
44 (3), pp. 207 - 213 (1996)
Use of nanogold- and fluorescent-labeled antibody Fv fragments in immunocytochemistry. Journal of Histochemistry and Cytochemistry
Journal Article
35 (48), pp. 15149 - 15161 (1996)
Glycosylation, Palmitoylation, and Localization of the Human D2S Receptor in Baculovirus-Infected Insect Cells. Biochemistry
Journal Article
35 (48), pp. 15162 - 15173 (1996)
In Vivo Reconstitution of Dopamine D2S Receptor-Mediated G Protein Activation in Baculovirus-Infected Insect Cells: Preferred Coupling to Gi1 versus Gi2. Biochemistry
Journal Article
35 (20), pp. 6500 - 6507 (1996)
Deletion of a B800-850 light-harvesting complex in Rhodospirillum molischianum DSM119 leads to "revertants" expressing a B800-820 complex: insights into pigment binding. Biochemistry 1995
Journal Article
377 (3), pp. 451 - 456 (1995)
Expression of functional mouse 5-HT5A serotonin receptor in the methylotrophic yeast Pichia pastoris: pharmacological characterization and localization. FEBS Letters
Journal Article
4 (9), pp. 1670 - 1682 (1995)
Predicting the structure of the light-harvesting complex II of Rhodospirillum molischianum. Protein Science
Journal Article
2 (10), pp. 842 - 846 (1995)
Fv fragment-mediated crystallization of the membrane protein bacterial cytochrome c oxidase. Nature Structural and Molecular Biology
Journal Article
34 (36), pp. 11335 - 11343 (1995)
Electron Transfer from the Tetraheme Cytochrome to the Special Pair in the Rhodopseudomonas viridis Reaction Center: Effect of Mutations of Tyrosine L162. Biochemistry
Journal Article
376 (6542), pp. 660 - 669 (1995)
Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans. Nature
Journal Article
231 (3), pp. 823 - 830 (1995)
Isolation and structural characterization of trimeric cyanobacterial photosystem I complex with the help of recombinant antibody fragments. European Journal of Biochemistry
Journal Article
1230 (3), pp. 147 - 154 (1995)
Spectroscopic properties of the light-harvesting complexes from Rhodospirillum molischianum. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
34 (25), pp. 7967 - 7972 (1995)
Interruption of the Water Chain in the Reaction Center from Rhodobacter sphaeroides Reduces the Rates of the Proton Uptake and of the Second Electron Transfer to QB. Biochemistry
Journal Article
43 (6), pp. 607 - 614 (1995)
Use of Antibody Fragments (Fv) in Immunocytochemistry. Journal of Histochemistry and Cytochemistry
Journal Article
230 (1), pp. 359 - 363 (1995)
Immunoelectron microscopy and epitope mapping with monoclonal antibodies suggest the existence of an additional N-terminal transmembrane helix in the cytochrome b subunit of bacterial ubiquinol: cytochrome-c oxidoreductases. European Journal of Biochemistry
Journal Article
246 (3), pp. 429 - 457 (1995)
Crystallographic refinement at 2.3 A resolution and refined model of the photosynthetic reaction centre from Rhodopseudomonas viridis. Journal of Molecular Biology (London)
Journal Article
155, pp. 155 - 160 (1995)
Engineered Fv Fragments as a Tool for the One-Step Purification of Integral Multisubunit Membrane Protein Complexes. Nature Biotechnology
Journal Article
21, pp. 74 - 77 (1995)
Crystals of an antibody FV fragment against an integral membrane protein diffracting to 1.28 Å resolution. Proteins: Structure, Function, and Bioinformatics 1994
Journal Article
226 (2), pp. 697 - 705 (1994)
Heterologous Expression of the Human D2S Dopamine Receptor in Protease‐Deficient Saccharomyces cerevisiae Strains. European Journal of Biochemistry
Journal Article
2 (10), pp. 925 - 936 (1994)
Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 A resolution: cofactors and protein-cofactor interactions. Structure
Journal Article
33 (37), pp. 11355 - 11363 (1994)
Structural and functional consequences of a Glu L212-->Lys mutation in the QB binding site of the photosynthetic reaction center of Rhodopseudomonas viridis. Biochemistry
Journal Article
1193 (2), pp. 255 - 262 (1994)
Constitutive expression of recombinant human D2S-dopamine receptor in the unicellular yeast Saccharomyces cerevisiae. Biochimica et Biophysica Acta-Biomembranes
Journal Article
344 (1), pp. 41 - 46 (1994)
Expression of the human D2S dopamine receptor in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe: a comparative study. FEBS Letters
Journal Article
26 (1), pp. 5 - 15 (1994)
Structure and Function of the Photosynthetic Reaction Center from Rhodobacter sphaeroides. Journal of Bioenergetics and Biomembranes 1993
Journal Article
234 (1), pp. 156 - 164 (1993)
Orthorhombic crystal form of bacteriorhodopsin nucleated on benzamidine diffracting to 3.6 A resolution. Journal of Molecular Biology (London)
Journal Article
113 (1), pp. 29 - 34 (1993)
Synthesis of the Rhodopseudomonas viridis holo-cytochrome c2 in Paracoccus denitrificans. FEMS Microbiology Letters
Journal Article
1174 (1), pp. 103 - 107 (1993)
Nucleotide sequence of a putative succinate dehydrogenase operon in Thermoplasma acidophilum. Biochimica et Biophysica Acta-Gene Structure and Expression
Journal Article
37, pp. 41 - 48 (1993)
Characterization of a Photosystem II core and its three-dimensional crystals. Photosynthesis Research
Journal Article
32 (21), pp. 5615 - 5621 (1993)
Unexpected similarities of the B800-850 light-harvesting complex from Rhodo-spirillum molischianum to the B870 light-harvesting complexes from other purple photosynthetic bacteria. Biochemistry
Journal Article
230 (4), pp. 1311 - 1314 (1993)
New Crystal Form of the Photosynthetic Reaction Centre from Rhodobacter sphaeroides of Improved Diffraction Quality. Journal of Molecular Biology (London)