Publications of Günter Fritzsch

Koepke, J.; Krammer, E.-M.; Klingen, A. R.; Sebban, P.; Ullmann, G. M.; Fritzsch, G.: pH Modulates the Quinone Position in the Photosynthetic Reaction Center from Rhodobacter sphaeroides in the Neutral and Charge Separated States. Journal of Membrane Biology 371 (2), pp. 396 - 409 (2007)

Katsemi, V.; Lücke, C.; Koepke, J.; Löhr, F.; Maurer, S.; Fritzsch, G.; Rüterjans, H.: Mutational and Structural Studies of the Diisopropylfluorophosphatase from Loligo vulgaris Shed New Light on the Catalytic Mechanism of the Enzyme. Biochemistry 44 (25), pp. 9022 - 9033 (2005)

Ma, X.; Koepke, J.; Panjikar, S.; Fritzsch, G.; Stöckigt, J.: Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily. The Journal of Biological Chemistry 280 (14), pp. 13576 - 13583 (2005)

Ma, X.; Koepke, J.; Fritzsch, G.; Diem, R.; Kutchan, T. M.; Michel, H.; Stöckigt, J.: Crystallization and preliminary X-ray crystallographic analysis of strictosidine synthase from Rauvolfia: the first member of a novel enzyme family. Biochimica et Biophysica Acta-Proteins and Proteomics 1702, pp. 121 - 124 (2004)

Ma, X.; Koepke, J.; Bayer, A.; Linhard, V.; Fritzsch, G.; Zhang, B.; Michel, H.; Stöckigt, J.: Vinorine synthase from Rauvolfia: the first example of crystallization and preliminary X-ray diffraction analysis of an enzyme of the BAHD superfamily. Biochimica et Biophysica Acta-Proteins and Proteomics 1701 (1-2), pp. 129 - 132 (2004)

Koepke, J.; Scharff, E. I.; Luecke, C.; Rueterjans, H.; Fritzsch, G.: Statistical analysis of crystallographic data obtained from squid ganglion DFPase at 0.85 Å resolution. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen) D59 (10), pp. 1744 - 1754 (2003)

Peng, G.; Fritzsch, G.; Zickermann, V.; Schaegger, H.; Mentele, R.; Lottspeich, F.; Bostina, M.; Radermacher, M.; Huber, R.; Stetter, K. O. et al.; Michel, H.: Isolation, Characterization and Electron Microscopic Single Particle Analysis of the NADH:Ubiquinone Oxidoreductase (Complex I) from the Hyperthermophilic Eubacterium Aquifex aeolicus. Biochemistry 42 (10), pp. 3032 - 3039 (2003)

Psylinakis, E.; Fritzsch, G.; Ghanotakis, D. F.: Isolation and crystallization of CP47, a Photosystem II chlorophyll binding protein. Degradation of CP47 upon dissociation from the core complex. Photosynthesis Research 72 (2), pp. 211 - 216 (2002)

Scharff, E. I.; Koepke, J.; Fritzsch, G.; Lücke, C.; Rüterjahns, H.: Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris. Structure 9 (6), pp. 493 - 502 (2001)

Kuglstatter, A.; Ermler, U.; Michel, H.; Baciou, L.; Fritzsch, G.: X-ray Structure Analyses of Photosynthetic Reaction Center Variants from Rhodobacter sphaeroides:  Structural Changes Induced by Point Mutations at Position L209 Modulate Electron and Proton Transfer. Biochemistry 40 (14), pp. 4253 - 4260 (2001)

Scharff, E. I.; Lücke, C.; Fritzsch, G.; Koepke, J.; Hartleib, J.; Dierl, S.; Rüterjans, H.: Crystallization and preliminary X-ray crystallographic analysis of DFPase from Loligo vulgaris. Acta Crystallographica Section D-Biological Crystallography 57 (1), pp. 148 - 149 (2001)

Kuglstatter, A.; Miksovska, J.; Sebban, P.; Fritzsch, G.: Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides reconstituted with anthraquinone as primary quinone Q_A. FEBS Letters (1), pp. 114 - 116 (2000)

Kuglstatter, A.; Hellwig, P.; Fritzsch, G.; Wachtveitl, J.; Oesterhelt, D.; Mäntele, W.; Michel, H.: Identification of a hydrogen bond in the Phe M197→Tyr mutant reaction center of the photosynthetic purple bacterium Rhodobacter sphaeroides by X-ray crystallography and FTIR spectroscopy. FEBS Letters 463 (1-2), pp. 169 - 174 (1999)

Fritzsch, G.; Kampmann, L.; Kapaun, G.; Michel, H.: Water clusters in the reaction centre of Rhodobacter sphaeroides. Photosynthesis Research 55, pp. 127 - 132 (1998)

Fyfe, P. K.; McAuley-Hecht, K. E.; Ridge, J. P.; Prince, S. M.; Fritzsch, G.; Isaacs, N. W.; Cogdell , R. J.; Jones, M. R.: Crystallographic studies of mutant reaction centres from Rhodobacter sphaeroides. Photosynthesis Research 55, pp. 133 - 140 (1998)

Somogyi, A. A.; Rumrich, G.; Fritzsch, G.; Ullrich, K. J.: Stereospecificity in contraluminal and luminal transporters of organic cations in the rat renal proximal tubule. Journal of Pharmacology and Experimental Therapeutics 278 (1), pp. 31 - 36 (1996)

Apostolakis, J.; Muegge, I.; Ermler, U.; Fritzsch, G.; Knapp, E.W.: Free Energy Computations on the Shift of the Special Pair Redox Potential:  Mutants of the Reaction Center of Rhodobacter sphaeroides. Journal of the American Chemical Society 118 (15), pp. 3743 - 3752 (1996)

Muegge, I.; Apostolakis, J.; Ermler, U.; Fritzsch, G.; Lubitz, W.; Knapp, E.W.: Shift of the Special Pair Redox Potential:  Electrostatic Energy Computations of Mutants of the Reaction Center from Rhodobacter sphaeroides. Biochemistry 35 (25), pp. 8359 - 8370 (1996)

Muegge, I.; Ermler, U.; Fritzsch, G.; Knapp, E. W.: Free Energy of Cofactors at the Quinone-Q_A Site of the Photosynthetic Reaction Center of Rhodobacter sphaeroides Calculated by Minimizing the Statistical Error. The Journal of Physical Chemistry 99 (51), pp. 17917 - 17925 (1995)

Ermler, U.; Fritzsch, G.; Buchanan, S. K.; Michel, H.: Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 A resolution: cofactors and protein-cofactor interactions. Structure 2 (10), pp. 925 - 936 (1994)

Scherer, P.O.J.; Fischer, S.F.; Lancaster, C. R. D.; Fritzsch, G.; Schmidt, S.; Arlt, T.; Dressler, K.; Zinth, W.: Time-resolved spectroscopy of the excited electronic state of reaction centers of Rhodopseudomonas viridis. Chemical Physics Letters 223 (1-2), pp. 110 - 115 (1994)

Ullrich, K. J.; Fritzsch, G.; Rumrich, G.; David, C.: Polysubstrates: substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: sulfamoyl-, sulfonylurea-, thiazide- and benzeneamino-carboxylate (nicotinate) compounds. Journal of Pharmacology and Experimental Therapeutics 269 (2), pp. 684 - 692 (1994)

Veyhl, M.; Spangenberg, J.; Püschel, B.; Poppe, R.; Dekel, C.; Fritzsch, G.; Haase, W.; Koepsell, H.: Cloning of a membrane-associated protein which modifies activity and properties of the Na⁺-D-glucose cotransporter. Journal of Biological Chemistry 268 (33), pp. 25041 - 25053 (1993)

Ullrich, K. J.; Rumrich, G.; David, C.; Fritzsch, G.: Bisubstrates: substances that interact with renal contraluminal organic anion and organic cation transport systems I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imidazoles, thiazoles, guanidines and hydrazines. Pflügers Archiv: European Journal of Physiology 425, pp. 280 - 299 (1993)

Ullrich, K. J.; Rumrich, G.; David, C.; Fritzsch, G.: Bisubstrates: substances that interact with renal contraluminal organic anion and organic cation transport systems II. Zwitterionic substrates: dipeptides, cephalosporins, quinolone-carboxylate gyrase inhibitors and phosphamide thiazine carboxylates; nonionizable substrates: steroid hormones and cyclophosphamides. Pflügers Archiv: European Journal of Physiology 425, pp. 300 - 312 (1993)

Fotinou, C.; Kokkinidis, M.; Fritzsch, G.; Haase, W.; Michel, H.; Ghanotakis, D. F.: Characterization of a Photosystem II core and its three-dimensional crystals. Photosynthesis Research 37, pp. 41 - 48 (1993)

Buchanan, S. K.; Fritzsch, G.; Ermler, U.; Michel, H.: New Crystal Form of the Photosynthetic Reaction Centre from Rhodobacter sphaeroides of Improved Diffraction Quality. Journal of Molecular Biology (London) 230 (4), pp. 1311 - 1314 (1993)

Betakis, E.; Fritzsch, G.; Zaki, L.: Inhibition of anion transport in the human red blood cell membrane with para- and meta-methoxyphenylglyoxal. Biochimica et Biophysica Acta, Bioenergetics 1110 (1), pp. 75 - 80 (1992)

Brändle, E.; Fritzsch, G.; Greven, J.: Affinity of different local anesthetic drugs and catecholamines for the contraluminal transport system for organic cations in proximal tubules of rat kidneys. Journal of Pharmacology and Experimental Therapeutics 260 (2), pp. 734 - 741 (1992)

Ullrich, K. J.; Rumrich, G.; Neiteler, K.; Fritzsch, G.: Contraluminal transport of organic cations in the proximal tubule of the rat kidney. Pflügers Archiv: European Journal of Physiology 420 (1), pp. 29 - 38 (1992)

Ullrich, K. J.; Papavassiliou, F.; David, C.; Rumrich, G.; Fritzsch, G.: Contraluminal transport of organic cations in the proximal tubule of the rat kidney. Pflügers Archiv: European Journal of Physiology 419, p. 84–92 (1991)

Sauer, H.; Pratsch, L.; Fritzsch, G.; Bhakdi, S.; Peters, R.: Complement pore genesis observed in erythrocyte membranes by fluorescence microscopic single-channel recording. Biochemical Journal 276 (2), pp. 395 - 399 (1991)

Ullrich, K. J.; Rumrich, G.; Papavassiliou, F.; Klöss, S.; Fritzsch, G.: Contraluminal p-aminohippurate transport in the proximal tubule of the rat kidney. VII. Specificity: cyclic nucleotides, eicosanoids. Pflügers Archiv: European Journal of Physiology 418 (4), pp. 360 - 370 (1991)

Frolov, E. N.; Birk, A.; Fritzsch, G.; Sinning, I. M.; Michel, H.; Goldanskii, V. I.; Parak, F.G.: Mössbauer spectroscopy on the reaction center of Rhodopseudomonas viridis. Hyperfine Interactions 68 (1), pp. 59 - 69 (1991)

Peters, R.; Sauer, H.; Tschopp, J.; Fritzsch, G.: Transients of perforin pore formation observed by fluorescence microscopic single channel recording. EMBO Journal 9 (8), pp. 2447 - 2451 (1990)

Michel, H.; Sinning, I.; Koepke, J.; Ewald, G.; Fritzsch, G.: The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis — An overview and recent advances. Biochimica et Biophysica Acta, Bioenergetics 1018 (1-2), pp. 115 - 118 (1990)

Jurzak, M.; Boer, R.; Fritzsch, G.; Kojro, E.; Fahrenholz, F.: Monoclonal antibodies against different epitopes of peptide hormones. European Journal of Biochemistry 190 (1), pp. 45 - 52 (1990)

Koepsell, H.; Fritzsch, G.; Korn, K.; Madrala, A.: Two substrate sites in the renal Na⁺-D-glucose cotransporter studied by model analysis of phlorizin binding and-D-glucose transport measurements. Journal of Membrane Biology 114 (2), pp. 113 - 132 (1990)

Ziegler, K.; Frimmer, M.; Fritzsch, G.; Koepsell, H.: Cyclosporin binding to a protein component of the renal Na⁺-D-glucose cotransporter. The Journal of Biological Chemistry 265 (6), pp. 3270 - 3277 (1990)

Fritzsch, G.; Buchanan, S.; Michel, H.: Assignment of cytochrome hemes in crystallized reaction centers from Rhodopseudomonas viridis. Biochimica et Biophysica Acta, Bioenergetics 977 (2), pp. 157 - 162 (1989)

Jakob, A.; Becker, J.; Schöttli, G.; Fritzsch, G.: α₁-Adrenergic stimulation causes Mg²⁺ release from perfused rat liver. FEBS Letters 246 (1-2), pp. 127 - 130 (1989)

Fritzsch, G.; Rumrich, G.; Ullrich, K. J.: Anion transport through the contraluminal cell membrane of renal proximal tubule: The influence of hydrophobicity and molecular charge distribution on the inhibitory activity of organic anions. Biochimica et Biophysica Acta-Biomembranes 978 (2), pp. 249 - 256 (1989)

Chakravarti, A.K.; Fritzsch, G.: Multicomponent ion-exchange equilibria. II. Prediction of ternary equilibria for the system Ca²⁺-Mg²⁺-H⁺ from the data of the component binary systems. Reactive and Functional Polymers 8 (1), pp. 51 - 68 (1988)

Ullrich, K. J.; Rumrich, G.; Fritzsch, G.; Klöss, S.: Contraluminal para-aminohippurate (PAH) transport in the proximal tubule of the rat kidney. I. Kinetics, influence of cations, anions, and capillary preperfusion. Pflügers Archiv: European Journal of Physiology 409 (3), pp. 229 - 235 (1987)

Fritzsch, G.: A kinetic analysis of enzyme inactivation as applied to the covalent modification of Na⁺ + K⁺-ATPase and Ca²⁺-ATPase. Journal of Theoretical Biology 117 (3), pp. 397 - 415 (1985)

Ullrich, K. J.; Rumrich, G.; Papavassiliou, F.; Fritzsch, G.: Contraluminal phosphate transport in the proximal tubule of the rat kidney. Pflügers Archiv: European Journal of Physiology 405 (Suppl 1), pp. S106 - S109 (1985)

Fahrenholz, F.; Boer, R.; Crause, P.; Fritzsch, G.; Grzonka, Z.: Interactions of vasopressin agonists and antagonists with membrane receptors. European Journal of Pharmacology 100 (1), pp. 47 - 58 (1984)

Fritzsch, G.; Haase, W.; Rumrich, G.; Fasold, H.; Ullrich, K. J.: A stopped flow capillary perfusion method to evaluate contraluminal transport parameters of methylsuccinate from interstitium into renal proximal tubular cells. Pflügers Archiv: European Journal of Physiology 400, pp. 250 - 256 (1984)

Fritzsch, G.; Koepsell, H.: An analysis of biphasic time courses: the inactivation of (Na⁺+K⁺)-ATPase and Ca²⁺-ATPase by ATP-analogs. Journal of Theoretical Biology 102 (4), pp. 469 - 476 (1983)

Kampmann, L.; Lepke, S.; Fasold, H.; Fritzsch, G.; Passow, H.: The kinetics of intramolecular cross-linking of the band 3 protein in the red blood cell membrane by 4,4'-diisothiocyano dihydrostilbene-2,2'-disulfonic acid (H₂DIDS). Journal of Membrane Biology 70 (3), pp. 199 - 216 (1982)

Koepsell, H.; Hulla, F. W.; Fritzsch, G.: Different classes of nucleotide binding sites in the (Na⁺ + K⁺)-ATPase studied by affinity labeling and nucleotide-dependent SH-group modifications. The Journal of Biological Chemistry 257 (18), pp. 10733 - 10741 (1982)

Seshadri, M.S.; Fritzsch, G.: The time evolution of sequential enzyme reactions: A singular perturbation approach. Journal of Theoretical Biology 93 (1), pp. 197 - 205 (1981)

Seshadri, M.S.; Fritzsch, G.: Analytical solutions of a simple enzyme kinetic problem by a perturbative procedure. Biophysics of structure and mechanism 6 (2), pp. 111 - 123 (1980)

Fritzsch, G.: Obtaining crystal structures from bacterial photosynthetic reaction centers. In: Methods in Enzymology, Vol. 297, pp. 57 - 77. Academic Press (1998)

Fritzsch, G.; Ermler, U.; Merckel, M. C.; Michel, H.: Crystallization and Structure of the Photosynthetic Reaction Centres from Rhodobacter sphaeroides - wild type and mutants. In: The Reaction Center of Photosynthetic Bacteria, pp. 3 - 13 (Ed. Michel-Beyerle, M.-E.). Springer, Berlin, Heidelberg (1996)

Ullrich, K. J.; Rumrich, G.; Fritzsch, G.: Substrate specificity of the organic anion and organic cation transport systems in the proximal renal tubule. In: Progress in Cell Research, Vol. 2, Chapter 31 Ed., pp. 315 - 321 (Eds. Bamberg, E.; Passow, H.). Elsevier B.V., Amsterdam (1992)

Koepke, J.; Scharff, E. I.; Lücke , C.; Rüterjans, H.; Fritzsch, G.: Atomic resolution crystal structure of squid ganglion DFPase. Proceedings of the 9th International Conference on the Crystallization of Biological Macromolecules, Jena, Germany, May 23, 2002 - May 28, 2002. Acta Crystallographica Section D-Biological Crystallography D58 (Part 10 Special Issue 1), pp. 1757 - 1759 (2002)

Fritzsch, G.; Koepke, J.; Diem, R.; Kuglstatter, A.; Baciou, L.: Charge separation induces conformational changes in the photosynthetic reaction centre of purple bacteria. Proceedings of the 9th International Conference on the Crystallization of Biological Macromolecules, Jena, Germany, March 23, 2002 - March 28, 2002. Acta Crystallographica Section D-Biological Crystallography D58 (Part 10 Special Issue 1), pp. 1660 - 1663 (2002)

Ermler, U.; Fritzsch, G.; Buchanan, S. K.; Michel, H.: Structure-function relationship in the photosynthetic reaction centre from the purple bacteria as revealed by X-ray crystallography analysis of a new trigonal crystal form of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 Å resolution. In: Research in Photosythesis, Vol. 1, pp. 341 - 347 (Ed. Murata, N.). Proceedings of the IXth International Congress on Photosynthesis, Nagoya, Japan, August 30, 1992 - September 04, 1992. Springer Science & Business Media, Kluwer Academic Publishers (1992)

Fritzsch, G.; Michel, H.: Linear Dichroism Spectra of Crystals from Bacterial Reaction Centers at various redox potentials and under the influence of light. In: Research in Photosynthesis, Vol. 1, pp. 397 - 400 (Ed. Murata, N.). Proceedings of the IXth International Congress on Photosynthesis, Nagoya, Japan, August 30, 1992 - September 04, 1992. Springer Science & Business Media, Kluwer Academic Press, Dordrecht, London (1992)