Publications of Helmut Reiländer

Cismasiu, V. B.; Denes, S. A.; Reiländer, H.; Michel, H.; Szedlacsek, S. E.: The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase µ. The Journal of Biological Chemistry 279 (26), pp. 26922 - 26931 (2004)

Maeda, Y.; Kuroki, R.; Haase, W.; Michel, H.; Reiländer, H.: Comparative analysis of high-affinity ligand binding and G protein coupling of the human CXCR1 chemokine receptor and of a CXCR1-G_i2α fusion protein after heterologous production in baculovirus-infected insect cells. European Journal of Biochemistry 271, pp. 1677 - 1689 (2004)

Grünewald, S.; Haase, W.; Molsberger, E.; Michel, H.; Reiländer, H.: Production of the Human D_2S Receptor in the Methylotrophic Yeast P. pastoris. Receptors and Channels 10 (1), pp. 37 - 50 (2004)

Hövelmann, S.; Hoffmann, S. H.; Kühne, R.; ter Laak, T.; Reiländer, H.; Beckers, T.: Impact of aromatic residues within transmembrane helix 6 of the human gonadotropin-releasing hormone receptor upon agonist and antagonist binding. Biochemistry 41 (4), pp. 1129 - 1136 (2002)

Ungar, D.; Barth, A.; Haase, W.; Kauntzinger, A.; Lewitzki, E.; Ruiz, T.; Reiländer, H.; Michel, H.: Analysis of a putative voltage-gated prokaryotic potassium channel. European Journal of Biochemistry 268 (20), pp. 5386 - 5396 (2001)

Schiller, H.; Molsberger, E.; Janssen , P.; Michel, H.; Reiländer, H.: Solubilization and purification of the human ETB endothelin receptor produced by high-level fermentation in Pichia pastoris. Receptors and Channels 7 (6), pp. 453 - 469 (2001)

Hoffmann, S.; ter Laak , T.; Kühne, R.; Reiländer, H.; Beckers, T.: Residues within Transmembrane Helices 2 and 5 of the Human Gonadotropin-Releasing Hormone Receptor Contribute to Agonist and Antagonist Binding. Molecular Endocrinology 14 (7), pp. 1099 - 1115 (2000)

Hampe, W.; Voss, R.-H.; Haase, W.; Boege, F.; Michel, H.; Reiländer, H.: Engineering of a proteolytically stable human β₂-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells. Journal of Biotechnology 77 (2-3), pp. 219 - 234 (2000)

Maeda, Y.; Kuroki, R.; Suzuki, H.; Reiländer, H.: High-Level Secretion of Biologically Active Recombinant Human Macrophage Inflammatory Protein-1α by the Methylotrophic Yeast Pichia pastoris. Protein Expression and Purification 18 (1), pp. 56 - 63 (2000)

Schiller, H.; Haase, W.; Molsberger, E.; Janssen, P.; Michel, H.; Reiländer, H.: The human ET(B) endothelin receptor heterologously produced in the methylotrophic yeast Pichia pastoris shows high-affinity binding and induction of stacked membranes. Receptors and Channels 7 (2), pp. 93 - 107 (2000)

Marheineke, K.; Grünewald, S.; Christie, W.; Reiländer, H.: Lipid composition of Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn) insect cells used for baculovirus infection. FEBS Letters 441 (1), pp. 49 - 52 (1998)

Marheineke, K.; Lenhard, T.; Haase, W.; Beckers, T.; Michel, H.; Reiländer, H.: Characterization of the Human Gonadotropin-Releasing Hormone Receptor Heterologously Produced Using the Baculovirus/Insect Cell and the Semliki Forest Virus Systems. Cellular and Molecular Neurobiology 18 (5), pp. 509 - 524 (1998)

Reiländer, H.; Weiß, M.: Production of G protein-coupled receptors in yeast. Current Opinion in Biotechnology 9 (5), pp. 510 - 517 (1998)

Ivanovic, A.; Reiländer, H.; Laube, B.; Kuhse, J.: Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit. The Journal of Biological Chemistry 273 (32), pp. 19933 - 19937 (1998)

Lenhard, T.; Marheineke, K.; Lingen, B.; Haase, W.; Hammermann, R.; Michel, H.; Reiländer, H.: Characterization of the Human Dopamine Transporter Heterologously Expressed in BHK-21 Cells. Cellular and Molecular Biology 18 (3), pp. 347 - 360 (1998)

Weiss, H. M.; Haase, W.; Michel, H.; Reiländer, H.: Comparative biochemical and pharmacological characterization of the mouse 5HT_5A 5-hydroxytryptamine receptor and the human beta2-adrenergic receptor produced in the methylotrophic yeast Pichia pastoris. Biochemical Journal 330 (3), pp. 1137 - 1147 (1998)

Lenhard, T.; Reiländer, H.: Engineering the folding pathway of insect cells: Generation of a stably transformed insect cell line showing improved folding of a recombinant membrane protein. Biochemical and Biophysical Research Communications 238 (3), pp. 823 - 830 (1997)

Beckers, T.; Reiländer, H.; Hilgard, P.: Characterization of Gonadotropin-Releasing Hormone Analogs Based on a Sensitive Cellular Luciferase Reporter Gene Assay. Analytical Biochemistry 251 (1), pp. 17 - 23 (1997)

Jahns, R.; Siegmund, C.; Jahns, V.; Reiländer, H.; Maidhof, A.; Müller-Esterl, W.; Lohse, M. J.; Boege, F.: Probing human β₁- and β₂-adrenoceptors with domain-specific fusion protein antibodies. European Journal of Pharmacology 316 (1), pp. 111 - 121 (1996)

Germeroth, L.; Reiländer, H.; Michel, H.: Molecular cloning, DNA sequence and transcriptional analysis of the Rhodospirillum molischianum B800/850 light-harvesting genes. Biochimica et Biophysica Acta, Bioenergetics 1275 (3), pp. 145 - 150 (1996)

Abd Alla, S.; Quitterer, U.; Schröder, C.; Blaukat, A.; Horstmeyer, A.; Dedio, J.; Reiländer, H.; Müller-Esterl, W.: On the structure of the amino-terminal domain ED 1 of the B2 receptor. Immunopharmacology 33 (1-3), pp. 42 - 45 (1996)

Lenhard, T.; Maul, G.; Haase, W.; Reiländer, H.: A new set of versatile vectors for the heterologous expression of foreign genes using the baculovirus system. Gene 169 (2), pp. 187 - 190 (1996)

Reiländer, H.; Haase, W.; Maul, G.: Functional Expression of the Aequorea victoria Green Fluorescent Protein in Insect Cells Using the Baculovirus Expression System. Biochemical and Biophysical Research Communications 219 (1), pp. 14 - 20 (1996)

Bach, M.; Sander, P.; Haase, W.; Reiländer, H.: Pharmacological and biochemical characterization of the mouse 5HT_5A serotonin receptor heterologously produced in the yeast Saccharomyces cerevisiae. Receptors and Channels 4 (2), pp. 129 - 139 (1996)

Grünewald, S.; Haase, W.; Reiländer, H.; Michel, H.: Glycosylation, Palmitoylation, and Localization of the Human D_2S Receptor in Baculovirus-Infected Insect Cells. Biochemistry 35 (48), pp. 15149 - 15161 (1996)

Grünewald, S.; Reiländer, H.; Michel, H.: In Vivo Reconstitution of Dopamine D_2S Receptor-Mediated G Protein Activation in Baculovirus-Infected Insect Cells:  Preferred Coupling to G_i1 versus G_i2. Biochemistry 35 (48), pp. 15162 - 15173 (1996)

Weiss, H. M.; Haase, W.; Michel, H.; Reiländer, H.: Expression of functional mouse 5-HT_5A serotonin receptor in the methylotrophic yeast Pichia pastoris: pharmacological characterization and localization. FEBS Letters 377 (3), pp. 451 - 456 (1995)

Marheineke, K.; Bach, M.; Haase, W.; Reiländer, H.: High level production and localization of bovine rod cGMP-gated cation channel subunit 1 in baculovirus-infected insect cells and Saccharomyces cerevisiae. Biochemical and Biophysical Research Communications 215 (3), pp. 961 - 967 (1995)

Gimpl, G.; Klein, U.; Reiländer, H.; Fahrenholz, F.: Expression of the Human Oxytocin Receptor in Baculovirus-infected Insect Cells: High-Affinity Binding Is Induced by a Cholesterol-Cyclodextrin Complex. Biochemistry 34 (42), pp. 13794 - 13801 (1995)

Beckers, T.; Marheineke, K.; Reiländer, H.; Hilgard, P.: Selection and characterization of mammalian cell lines with stable over-expression of human pituitary receptors for gonadoliberin. European Journal of Biochemistry 231 (3), pp. 535 - 543 (1995)

Vasudevan, S.; Hulme, E. C.; Bach, M.; Haase, W.; Pavia, J.; Reiländer, H.: Characterization of the rat m3 muscarinic acetylcholine receptor produced in insect cells infected with recombinant baculovirus. European Journal of Biochemistry 227 (1-2), pp. 466 - 475 (1995)

Sander, P.; Grünewald, S.; Bach, M.; Haase, W.; Reiländer, H.; Michel, H.: Heterologous Expression of the Human D_2S Dopamine Receptor in Protease‐Deficient Saccharomyces cerevisiae Strains. European Journal of Biochemistry 226 (2), pp. 697 - 705 (1994)

Heithier, H.; Hallmann, D.; Boege, F.; Reiländer, H.; Dees, C.; Jaeggi, K. D.; Arndt-Jovin, D. J.; Jovin, T. M.; Helmreich, E. J. M.: Synthesis and properties of fluorescent ß-adrenoceptor ligands. Biochemistry 33 (31), pp. 9126 - 9134 (1994)

Sander, P.; Grünewald, S.; Maul, G.; Reiländer, H.; Michel, H.: Constitutive expression of recombinant human D_2S-dopamine receptor in the unicellular yeast Saccharomyces cerevisiae. Biochimica et Biophysica Acta-Biomembranes 1193 (2), pp. 255 - 262 (1994)

Sander, P.; Grünewald, S.; Reiländer, H.; Michel, H.: Expression of the human D_2S dopamine receptor in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe: a comparative study. FEBS Letters 344 (1), pp. 41 - 46 (1994)

Bach, M.; Reiländer, H.; Gärtner, P.; Lottspeich, F.; Michel, H.: Nucleotide sequence of a putative succinate dehydrogenase operon in Thermoplasma acidophilum. Biochimica et Biophysica Acta-Gene Structure and Expression 1174 (1), pp. 103 - 107 (1993)

Tripp, H.; Reiländer, H.; Wild, A.: A Rapid Method for Amplification of Plastome DNA-Fragments from Spinacia oleracea by PCR. Journal of Plant Physiology 142 (1), pp. 115 - 116 (1993)

Kleymann, G.; Boege, F.; Hahn, M.; Hampe, W.; Vasudevan, S.; Reiländer, H.: Human beta 2-adrenergic receptor produced in stably transformed insect cells is functionally coupled via endogenous GTP-binding protein to adenylyl cyclase. European Journal of Biochemistry 213 (2), pp. 797 - 804 (1993)

Vasudevan, S.; Premkumar, L.; Stowe, S.; Gage, P. A.; Reiländer, H.; Chung, S.-H.: Muscarinic acetylcholine receptor produced in recombinant baculovirus infected Sf9 insect cells couples with endogenous G-proteins to activate ion channels. FEBS Letters 311 (1), pp. 7 - 11 (1992)

Reiländer, H.; Achilles, A.; Friedel, U.; Maul, G.; Lottspeich, F.; Cook, N. J.: Primary structure and functional expression of the Na/Ca,K-exchanger from bovine rod photoreceptors. The EMBO Journal 11 (5), pp. 1689 - 1695 (1992)

Achilles, A.; Friedel, U.; Haase, W.; Reiländer, H.; Cook, N. J.: Biochemical and molecular characterization of the sodium-calcium exchanger from bovine rod photoreceptors. Annals of the New York Academy of Sciences 639 (1), pp. 234 - 244 (1991)

Vasudevan, S.; Reiländer, H.; Maul, G.; Michel, H.: Expression and cell membrane localization of rat M3 muscarinic acetylcholine receptor produced in Sf9 insect cells using the baculovirus system. FEBS Letters 283 (1), pp. 52 - 56 (1991)

Reiländer, H.; Boege, F.; Vasudevan, S.; Maul, G.; Hekmann, M.; Dees, C.; Hampe, W.; Helmreich, E. J.M.; Michel, H.: Purification and functional characterization of the human ß2-adrenergic receptor produced in baculovirus-infected insect cells. FEBS Letters 282 (2), pp. 441 - 444 (1991)

Wendeler, M.; Reiländer, H.; Hoernschemeyer, J.; Schwarzmann, G.; Kolter, T.; Sandhoff, K.: Recombinant ganglioside G_M2-synthase-expression in insect cells and enzyme assay. In: Methods in Enzymology, Vol. 363, pp. 476 - 489 (Eds. Yuan C. Lee; Reiko T. Lee). Elsevier Inc (2003)

Haase, W.; Weiß, H. M.; Reiländer, H.: Localization of the myc-Tagged 5HT_5A Receptor by Immunogold Staining of Ultrathin Sections. In: Methods in Molecular Biology, Vol. 103, 16, pp. 241 - 247 (Eds. Higgins, D. R.; Cregg, J. M.). Humana Press, Totowa, New Jersey (1998)

Weiß, H. M.; Haase, W.; Reiländer, H.: Expression of an Integral Membrane Protein, the 5HT_5A Receptor. In: Methods in Molecular Biology, Vol. 103, 15, pp. 227 - 239 (Ed. Higgins, D. R.). Humana Press 1998, Totowa, New Jersey (1998)

Behr, J.; Haase, W.; Maul, G.; Vasudevan; Reiländer, H.: Effect of N-glycosylation on production of the rat m3 muscarinic acetylcholine receptor in baculovirus-infected insect cells. Advances in Ultracentrifuge Analysis 666th Meeting , University of Sheffield, UK, 1998. Biochemical Society Transactions 26 (4), 4 Ed., pp. 704 - 709 (1998)

Reiländer, H.: G-Protein-gekoppelte Rezeptoren: pharmakologische und biochemische Charakterisierung, Solubilisierung und Reinigung nach heterologer Produktion in verschiedenen Expressionssystemen. Habilitation, 279 pp., Fachbereich Chemische und pharmazeutische Wissenschaften der Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2003)