Publications of Melanie Radloff

Zöller, J.; Hong, S.; Eisinger, M. L.; Anderson, M.; Radloff, M.; Desch, K.; Gennis, R.; Langer, J. D.: Ligand binding and conformational dynamics of the E. coli nicotinamide nucleotide transhydrogenase revealed by hydrogen/deuterium exchange mass spectrometry. Computational and Structural Biotechnology Journal 20, pp. 5430 - 5439 (2022)

Grund, T. N.; Radloff, M.; Wu, D.; Goojani, H. G.; Witte, L. F.; Jösting, W.; Buschmann, S.; Müller, H.; Elamri, I.; Welsch, S. et al.; Schwalbe, H.; Michel, H.; Bald, D.; Safarian, S.: Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 118 (50), e2114013118 (2021)

Radloff, M.; Elamri, I.; Grund, T. N.; Witte, L. F.; Hohmann, K. F.; Nakagaki, S.; Goojani , H. G.; Nasiri, H.; Miyoshi , H.; Bald, D. et al.; Xie, H.; Sakamoto, J.; Schwalbe, H.; Safarian, S.: Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases. Scientific Reports 11 (1), e23852 (2021)

Safarian, S.; Opel-Reading, H. K.; Wu, D.; Mehdipour, A. R.; Hards, K.; Harold, L. H.; Radloff, M.; Stewart, I.; Welsch, S.; Hummer, G. et al.; Cook, G. M.; Krause, K. L.; Michel, H.: The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications 12 (1), 5236 (2021)

Elamri, I.; Radloff, M.; Hohmann, K. F.; Nimbarte, V. D.; Nasiri, H. R.; Bolte, M.; Safarian, S.; Michel, H.; Schwalbe, H.: Synthesis and Biological Screening of new Lawson Derivatives as selective substrate‐based Inhibitors of Cytochrome bo₃ Ubiquinol Oxidase from Escherichia coli. ChemMedChem 15 (14), pp. 1262 - 1271 (2020)

Safarian, S.; Hahn, A.; Mills, D.; Radloff, M.; Eisinger, M. L.; Nikolaev, A.; Meier-Credo, J.; Melin, F.; Miyoshi, H.; Gennis, R.B. et al.; Sakamoto, J.; Langer, J. D.; Hellwig, P.; Kühlbrandt, W.; Michel, H.: Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 366 (6461), pp. 100 - 104 (2019)

Radloff, M.: Functional characterization of cytochrome bd-I oxidase from E. coli as a potential antimicrobial target. Dissertation, 117 pp., Fachbereich 14, Biochemie, Chemie und Pharmazie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2022)