Publikationen von Lucy R. Forrest

Fowler, P. W.; Orwick-Rydmark, M.; Radestock, S.; Solcan, N.; Dijkman, P. M.; Lyons, J. A.; Kwok, J.; Caffrey, M.; Watts, A.; Forrest, L. R. et al.; Newstead, S.: Gating Topology of the Proton-Coupled Oligopeptide Symporters. Structure 23 (2), S. 290 - 301 (2015)

Schweikhard, E. S.; Burckhardt, B. C.; Joos, F.; Fenollar-Ferrer, C.; Forrest, L. R.; Kempson, S. A.; Ziegler, C.: Role of N-glycosylation in renal betaine transport. Biochemical Journal 470 (2), S. 169 - 179 (2015)

Fenollar-Ferrer, C.; Stockner, T.; Schwarz, T. C.; Pal, A.; Gotovina, J.; Hofmaier, T.; Jayaraman, K.; Adhikary, S.; Kudlacek, O.; Mehdipour, A. R. et al.; Tavoulari, S.; Rudnick, G.; Singh, S. K.; Konrat, R.; Sitte, H. H.; Forrest, L. R.: Structure and Regulatory Interactions of the Cytoplasmic Terminal Domains of Serotonin Transporter. Biochemistry 53 (33), S. 5444 - 5460 (2014)

Perez, C.; Faust, B.; Mehdipour, A. R.; Francesconi, K. A.; Forrest, L. R.; Ziegler, C.: Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na⁺ coupling. Nature Communications 5, 4231 (2014)

Stamm, M.; Staritzbichler, R.; Khafizov, K.; Forrest, L. R.: AlignMe-a membrane protein sequence alignment web server. Nucleic Acids Research 42 (W1), S. W246 - W251 (2014)

Fenollar-Ferrer, C.; Patti, M.; Knöpfel, T.; Werner, A.; Forster, I. C.; Forrest, L. R.: Structural Fold and Binding Sites of the Human Na⁺-Phosphate Cotransporter NaPi-II. Biophysical Journal 106 (6), S. 1268 - 1279 (2014)

Yaffe, D.; Radestock, S.; Shuster, Y.; Forrest, L. R.; Schuldiner, S.: Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences of the United States of America 110 (15), S. E1332 - E1341 (2013)

Stamm, M.; Staritzbichler, R.; Khafizov, K.; Forrest, L. R.: Alignment of Helical Membrane Protein Sequences Using AlignMe. PLoS One 8 (3), e57731 (2013)

Forrest, L. R.: (Pseudo-)Symmetrical Transport. Science 339 (6118), S. 339 - 401 (2013)

Silverstein, N.; Crisman, T. J.; Forrest, L. R.; Kanner, B. I.: Cysteine Scanning Mutagenesis of Transmembrane Helix 3 of a Brain Glutamate Transporter Reveals Two Conformationally Sensitive Positions. The Journal of Biological Chemistry 288 (2), S. 964 - 973 (2013)

Gradogna, A.; Fenollar-Ferrer, C.; Forrest, L. R.; Pusch, M.: Dissecting a regulatory calcium-binding site of CLC-K kidney chloride channels. Journal of General Physiology 140 (6), S. 681 - 696 (2012)

Khafizov, K.; Perez, C.; Koshy, C.; Quick, M.; Fendler, K.; Ziegler, C.; Forrest, L. R.: Investigation of the sodium binding sites in the betaine transporter BetP. Proceedings of the National Academy of Sciences of the United States of America 109 (44), S. E3035 - E3045 (2012)

Schushan, M.; Rimon, A.; Haliloglu, T.; Forrest, L. R.; Padan, E.; Ben-Tal, N.: A Model-Structure of a Periplasm-facing State of the NhaA Antiporter Suggests the Molecular Underpinnings of pH-induced Conformational Changes. The Journal of Biological Chemistry 287 (22), S. 18249 - 18261 (2012)

Perez, C.; Khafizov, K.; Forrest, L. R.; Krämer, R.; Ziegler, C.: The role of trimerization in the osmoregulated betaine transporter BetP. EMBO Reports 12 (8), S. 804 - 810 (2011)

Radestock, S.; Forrest, L. R.: The Alternating-Access Mechanism of MFS Transporters Arises from Inverted-Topology Repeats. Journal of Molecular Biology 407 (5), S. 698 - 715 (2011)

Staritzbichler, R.; Anselmi, C.; Forrest, L. R.; Faraldo-Gómez, J. D.: GRIFFIN: A Versatile Methodology for Optimization of Protein-Lipid Interfaces for Membrane Protein Simulations. Journal of Chemical Theory and Computation 7 (4), S. 1167 - 1176 (2011)

Faraldo-Gómez, J. D.; Forrest, L. R.: Modeling and simulation of ion-coupled and ATP-driven membrane proteins. Current Opinion in Structural Biology 21 (2), S. 173 - 179 (2011)

Tsai, C.-J.; Khafizov, K.; Hakulinen, J.; Forrest, L. R.; Krämer, R.; Kühlbrandt, W.; Ziegler, C.: Structural Asymmetry in a Trimeric Na⁺/Betaine Symporter, BetP, from Corynebacterium glutamicum. Journal of Molecular Biology 407 (3), S. 368 - 381 (2011)

Forrest, L. R.; Krämer, R.; Ziegler, C.: The structural basis of secondary active transport mechanisms. Biochimica et Biophysica Acta, Bioenergetics 1807 (2), S. 167 - 188 (2011)

Tavoulari, S.; Rizwan, A. N.; Forrest, L. R.; Rudnick, G.: Reconstructing a Chloride-binding Site in a Bacterial Neurotransmitter Transporter Homologue. The Journal of Biological Chemistry 286 (4), S. 2834 - 2842 (2011)

Khafizov, K.; Staritzbichler, R.; Stamm, M.; Forrest, L. R.: A Study of the Evolution of Inverted-Topology Repeats from LeuT-Fold Transporters Using AlignMe. Biochemistry 49 (50), S. 10702 - 10713 (2010)

Crisman, T. J.; Qu, S.; Kanner, B. I.; Forrest, L. R.: Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats. Proceedings of the National Academy of Sciences of the United States of America 106 (49), S. 20752 - 20757 (2009)

Forrest, L. R.; Rudnick, G.: The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters. Physiology 24 (6), S. 377 - 386 (2009)

Tavoulari, S.; Forrest, L. R.; Rudnick, G.: Fluoxetine (Prozac) Binding to Serotonin Transporter Is Modulated by Chloride and Conformational Changes. The Journal of Neuroscience 29 (30), S. 9635 - 9643 (2009)

Trötschel, C.; Follmann, M.; Nettekoven, J. A.; Mohrbach, T.; Forrest, L. R.; Burkovski, A.; Marin, K.; Krämer, R.: Methionine Uptake in Corynebacterium glutamicum by MetQNI and by MetPS, a Novel Methionine and Alanine Importer of the NSS Neurotransmitter Transporter Family. Biochemistry 47 (48), S. 12698 - 12709 (2008)

Khafizov, K.; Perez, C.; Tsai, C.-J.; Ziegler, C.; Forrest, L. R.: Computational and Experimental Studies of Substrate Binding, Conformational Change and Importance of the Trimeric State in the Glycine Betaine Transporter BetP. Biophysical Journal (Annual Meeting Abstracts) 100 (3, Supplement 1), S. 132a - 132a (2011)