Publications of Werner Kühlbrandt
All genres
Journal Article (226)
1.
Journal Article
Cryo-EM structure of the NDH-PSI-LHCI supercomplex from Spinacia oleracea. Nature Structural & Molecular Biology (2025)
2.
Journal Article
12 (1) (2025)
Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM. IUCrJ 3.
Journal Article
385 (6713), pp. 1086 - 1090 (2024)
In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells. Science 4.
Journal Article
32 (7), pp. 979 - 988.e4 (2024)
Complementary structures of the yeast phosphate transporter Pho90 provide insights into its transport mechanism. Structure 5.
Journal Article
120 (34), e2301447120 (2023)
Two conformations of the Tom20 preprotein receptor in the TOM holo complex. Proceedings of the National Academy of Sciences of the United States of America 6.
Journal Article
9, pp. 142 - 156 (2023)
Cryo-EM structure of the respiratory I + III2 supercomplex from Arabidopsis thaliana at 2 Å resolution. Nature Plants 7.
Journal Article
10 (1), pp. 27 - 37 (2023)
Analysis of the conformational heterogeneity of the Rieske iron–sulfur protein in complex III2 by cryo-EM. IUCrJ 8.
Journal Article
8 (47), eadc9952 (2022)
Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Science Advances 9.
Journal Article
8 (46), eadd3855 (2022)
Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling. Science Advances 10.
Journal Article
240, pp. 323 - 335 (2022)
Concluding remarks: Challenges and future developments in biological electron cryo-microscopy. Faraday Discussions 11.
Journal Article
13 (1), 6091 (2022)
Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations. Nature Communications 12.
Journal Article
13, 2708 (2022)
Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria. Nature Communications 13.
Journal Article
71 (Supplement 1), pp. i30 - i50 (2022)
Forty years in cryoEM of membrane proteins. Microscopy 14.
Journal Article
7 (52), eabk2392 (2021)
Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle. Science Advances 15.
Journal Article
7 (46), eabj3221 (2021)
High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances 16.
Journal Article
7 (46), eabj5255 (2021)
Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances 17.
Journal Article
33 (6), pp. 2072 - 2091 (2021)
A ferredoxin bridge connects the two arms of plant mitochondrial complex I. The Plant Cell 18.
Journal Article
7 (4), pp. 514 - 523 (2021)
Molecular landscape of etioplast inner membranes in higher plants. Nature Plants 19.
Journal Article
54, e4 (2021)
Current limitations to high-resolution structure determination by single-particle cryoEM. Quarterly Reviews of Biophysics 20.
Journal Article
8 (Pt 2), pp. 186 - 194 (2021)
Devitrification reduces beam-induced movement in cryo-EM. IUCrJ 21.
Journal Article
117 (10), pp. 5109 - 5110 (2020)
Reply to Desikan et al.: Micelle formation among various mechanisms of toxin pore formation. Proceedings of the National Academy of Sciences of the United States of America 22.
Journal Article
7 (Pt 2), pp. 220 - 227 (2020)
The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase. IUCrJ 23.
Journal Article
124 (2), pp. 336 - 344 (2020)
Ion Binding and Selectivity of the Na+/H+ Antiporter MjNhaP1 from Experiment and Simulation. The Journal of Physical Chemistry B 24.
Journal Article
5 (12), p. eaax9484 (2019)
High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Science Advances 25.
Journal Article
6, pp. 1099 - 1105 (2019)
A comparative study of single-particle cryo-EM with liquid-nitrogen and liquid-helium cooling. IUCrJ 26.
Journal Article
366 (6461), pp. 100 - 104 (2019)
Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 27.
Journal Article
571 (7765), pp. 429 - 433 (2019)
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Nature 28.
Journal Article
571 (7765), pp. 366 - 370 (2019)
Structure and autoregulation of a P4-ATPase lipid flippase. Nature 29.
Journal Article
116 (27), pp. 13352 - 13357 (2019)
Membrane perforation by the pore-forming toxin pneumolysin. Proceedings of the National Academy of Sciences of the United States of America 30.
Journal Article
6 (4), pp. 773 - 780 (2019)
Cryo-EM structure of Neurospora crassa respiratory complex IV. IUCrJ 31.
Journal Article
13 (6), pp. 7185 - 7190 (2019)
Noncovalent Functionalization of Carbon Substrates with Hydrogels Improves Structural Analysis of Vitrified Proteins by Electron Cryo-Microscopy. ACS Nano 32.
Journal Article
364 (6446), eaaw9128, p. 1155 (2019)
Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. Science 33.
Journal Article
10, 1742 (2019)
Mechanism of the electroneutral sodium/proton antiporter PaNhaP from transition-path shooting. Nature Communications 34.
Journal Article
8, e42747 (2019)
Protein denaturation at the air-water interface and how to prevent it. eLife 35.
Journal Article
116 (10), pp. 4250 - 4255 (2019)
Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows. Proceedings of the National Academy of Sciences of the United States of America 36.
Journal Article
88, pp. 515 - 549 (2019)
Structure and Mechanisms of F-Type ATP Synthases. Annual Review of Biochemistry 37.
Journal Article
7, e39213 (2018)
Cryo-EM structure of respiratory complex I at work. eLife 38.
Journal Article
9, 1728 (2018)
Structural basis for energy transduction by respiratory alternative complex III. Nature Communications 39.
Journal Article
115 (12), pp. 3024 - 3029 (2018)
Conserved in situ arrangement of complex I and III2 in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants. Proceedings of the National Academy of Sciences of the United States of America 40.
Journal Article
115 (13), pp. E2906 - E2907 (2018)
Structure of the catalytic F1 head of the F1-Fo ATP synthase from Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America 41.
Journal Article
360 (6389), pp. 1 - 10 (2018)
Structure, mechanism, and regulation of the chloroplast ATP synthase. Science 42.
Journal Article
6, 10.7554/eLife.30483 (2017)
Cryo-EM structure of the bifunctional secretin complex of Thermus thermophilus. eLife 43.
Journal Article
6, e33274 (2017)
Structural basis of proton translocation and force generation in mitochondrial ATP synthase. eLife 44.
Journal Article
170 (4), pp. 693 - 700 (2017)
Cryo-EM Structure of the TOM Core Complex from Neurospora crassa. Cell 45.
Journal Article
6, e24662 (2017)
Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. eLife 46.
Journal Article
6, e27470 (2017)
Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery. eLife 47.
Journal Article
6, e23644 (2017)
CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin. eLife 48.
Journal Article
114 (5), pp. 992 - 997 (2017)
In situ structure of trypanosomal ATP synthase dimer reveals a unique arrangement of catalytic subunits. Proceedings of the National Academy of Sciences of the United States of America 49.
Journal Article
8, 2073, p. 1 (2017)
Structure of outer membrane protein G in lipid bilayers. Nature Communications 50.
Journal Article
11 (6), pp. 6467 - 6473 (2017)
Self-Perforated Hydrogel Nanomembranes Facilitate Structural Analysis of Proteins by Electron Cryo-Microscopy. ACS Nano 51.
Journal Article
18 (6), pp. 1 - 10 (2017)
Molecular architecture of the N‐type ATPase rotor ring from Burkholderia pseudomallei. EMBO Reports 52.
Journal Article
24 (2), pp. 123 - 130 (2017)
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2. Nature Structural and Molecular Biology 53.
Journal Article
291 (52), pp. 26786 - 26793 (2016)
Electrogenic Cation Binding in the Electroneutral Na+/H+ Antiporter of Pyrococcus abyssi. The Journal of Biological Chemistry 54.
Journal Article
5, e21290 (2016)
Functional asymmetry and electron flow in the bovine respirasome. eLife 55.
Journal Article
5, e14618 (2016)
A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro. eLife 56.
Journal Article
1857 (12), pp. 1935 - 1942 (2016)
Cryo-EM structure of respiratory complex I reveals a link to mitochondrial sulfur metabolism. Biochimica et Biophysica Acta (BBA) - Bioenergetics 57.
Journal Article
194 (3), pp. 375 - 382 (2016)
Supramolecular organization of the human N-BAR domain in shaping the sarcolemma membrane. Journal of Structural Biology 58.
Journal Article
63, pp. 1 - 12 (2016)
Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology. Molecular Cell 59.
Journal Article
35 (8), pp. 793 - 795 (2016)
Three in a row - how sodium ions cross the channel. The EMBO Journal 60.
Journal Article
41 (1), pp. 106 - 116 (2016)
Rotary ATPases: A New Twist to an Ancient Machine. Trends in biochemical sciences 61.
Journal Article
113 (30), pp. 8442 - 8447 (2016)
Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria. Proceedings of the National Academy of Sciences of the United States of America 62.
Journal Article
3 (1), pp. 3 - 7 (2016)
CryoEM at IUCrJ: a new era. International Union of Crystallography Journal (IUCrJ) 63.
Journal Article
4, e09375 (2015)
Mechanism of Na+-dependent citrate transport from the structure of an asymmetrical CitS dimer. eLife 64.
Journal Article
13 (89), pp. 1 - 11 (2015)
Structure and function of mitochondrial membrane protein complexes. BMC Biology 65.
Journal Article
153 (June), pp. 22 - 31 (2015)
Towards an optimum design for electrostatic phase plates. Ultramicroscopy 66.
Journal Article
4, e07380 (2015)
Structure of a type IV pilus machinery in the open and closed state. eLife 67.
Journal Article
521, pp. 237 - 240 (2015)
Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase. Nature 68.
Journal Article
4, e06119 (2015)
Bovine F1F0 ATP synthase monomers bend the lipid bilayer in 2D membrane crystals. eLife 69.
Journal Article
21 (5), pp. 747 - 755 (2015)
Central Role of Mic10 in the Mitochondrial Contact Site and Cristae Organizing System. Cell Metabolism 70.
Journal Article
112 (36), pp. 11288 - 11293 (2015)
Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid. Proceedings of the National Academy of Sciences of the United States of America 71.
Journal Article
427 (2), pp. 341 - 349 (2015)
Light-Induced Helix Movements in Channelrhodopsin-2. J. Mol. Biol. 72.
Journal Article
119 (10), pp. 3920 - 3930 (2015)
Protein Dynamics Tunes Excited State Positions in Light-Harvesting Complex II. The Journal of Physical Chemistry B 73.
Journal Article
3, e03583 (2014)
Structure and transport mechanism of the sodium/proton antiporter MjNhaP1. eLife 74.
Journal Article
3, e03579 (2014)
Structure and substrate ion binding in the sodium/proton antiporter PaNhaP. eLife 75.
Journal Article
21 (10), pp. 841 - 845 (2014)
A 3D cellular context for the macromolecular world. Nature Structural and Molecular Biology 76.
Journal Article
3, e03678 (2014)
Microscopy: Cryo-EM enters a new era. eLife 77.
Journal Article
5, 4129 (2014)
Visualizing active membrane protein complexes by electron cryotomography. Nature Communications 78.
Journal Article
289, pp. 13168 - 13176 (2014)
Keeping It Simple, Transport Mechanism and pH Regulation in Na+/H+. The Journal of Biological Chemistry 79.
Journal Article
343 (6178), pp. 1443 - 1444 (2014)
The Resolution Revolution. Science 80.
Journal Article
3, e01963 (2014)
Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector. eLife 81.
Journal Article
3, e01412 (2014)
pH- and sodium-induced changes in a sodium/proton antiporter. eLife 82.
Journal Article
111 (10), pp. 3829 - 3834 (2014)
Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids. Proceedings of the National Academy of Sciences of the United States of America 83.
Journal Article
Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography. Journal of Visualized Experiments (91 doi: 10.3791/51228), e51228 (2014)
84.
Journal Article
5, 3690 (2014)
Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation. Nature Communications 85.
Journal Article
23 (10), pp. 2580 - 2592 (2014)
Loss of LRPPRC causes ATP synthase deficiency. Human Molecular Genetics 86.
Journal Article
87 (24), pp. 13379 - 13385 (2013)
First insights into the entry process of hyperthermophilic archaeal viruses. Journal of Virology 87.
Journal Article
110 (43), pp. 17296 - 17301 (2013)
Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT. Proceedings of the National Academy of Sciences of the United States of America 88.
Journal Article
110 (38), pp. 15301 - 15306 (2013)
Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria. Proceedings of the National Academy of Sciences of the United States of America 89.
Journal Article
110 (14), pp. 5452 - 5456 (2013)
Direct interaction of the major light-harvesting complex II and PsbS in nonphotochemical quenching. Proceedings of the National Academy of Sciences of the United States of America 90.
Journal Article
109 (34), pp. 13602 - 13607 (2012)
Structure of the yeast F1F0-ATP synthase dimer and its role in shaping the mitochondrial cristae. Proceedings of the National Academy of Sciences of the United States of America 91.
Journal Article
51 (33), pp. 8343 - 8347 (2012)
GRecon: A Method for the Lipid Reconstitution of Membrane Proteins. Angewandte Chemie, International Edition in English 92.
Journal Article
116, pp. 62 - 72 (2012)
Practical aspects of Boersch phase contrast electron microscopy of biological specimens. Ultramicroscopy 93.
Journal Article
1 (1), pp. 21 - 28 (2012)
Structure of the SecY Complex Unlocked by a Preprotein Mimic. Cell Reports 94.
Journal Article
111 (12), pp. 1696 - 1705 (2011)
In-focus electron microscopy of frozen-hydrated biological samples with a Boersch phase plate. Ultramicroscopy 95.
Journal Article
286 (47), pp. 40954 - 40961 (2011)
Structure of Human Na+/H+ Exchanger NHE1 Regulatory Region in Complex with Calmodulin and Ca2+. The Journal of Biological Chemistry 96.
Journal Article
414 (1), pp. 86 - 95 (2011)
Projection Structure of Channelrhodopsin-2 at 6 Å Resolution by Electron Crystallography. Journal of Molecular Biology 97.
Journal Article
13 (11), pp. 1744 - 1754 (2011)
Outer membrane continuity and septosome formation between vegetative cells in the filaments of Anabaena sp. PCC 7120. Cellular Microbiology 98.
Journal Article
99 (3), 133701 (2011)
Single-walled carbon nanotubes and nanocrystalline graphene reduce beam-induced movements in high-resolution electron cryo-microscopy of ice-embedded biological samples. Applied Physics Letters 99.
Journal Article
108 (34), pp. 14121 - 14126 (2011)
Macromolecular organization of ATP synthase and complex I in whole mitochondria. Proceedings of the National Academy of Sciences of the United States of America 100.
Journal Article
108 (33), pp. 13841 - 13846 (2011)
Chloroplast Omp85 proteins change orientation during evolution. Proceedings of the National Academy of Sciences of the United States of America