
Publikationen des Max-Planck-Institutes für Biophysik
Zeitschriftenartikel (83)
2021
Zeitschriftenartikel
7 (52), eabk2392 (2021)
Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle. Science Advances
Zeitschriftenartikel
94 (12), 245 (2021)
Empirical optimization of molecular simulation force fields by Bayesian inference. The European Physical Journal B: Condensend Matter Physics
Zeitschriftenartikel
24 (12), e103524 (2021)
Closantel is an allosteric inhibitor of human Taspase1. iScience
Zeitschriftenartikel
118 (50), e2114013118 (2021)
Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America
Zeitschriftenartikel
57 (96), S. 12948 - 12951 (2021)
Rational engineering of Luminiphilus syltensis ( R)-selective amine transaminase for the acceptance of bulky substrates. Chemical Communications
Zeitschriftenartikel
11 (1), e23852 (2021)
Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases. Scientific Reports
Zeitschriftenartikel
374 (6573), eabd9776 (2021)
Nuclear pores dilate and constrict in cellulo. Science
Zeitschriftenartikel
12 (1), 6982 (2021)
Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases. Nature Communications
Zeitschriftenartikel
12, 6903 (2021)
Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase. Nature Communications
Zeitschriftenartikel
81, S. 4635 - 4649 (2021)
Structural basis of polyamine transport by human ATP13A2 (PARK9). Molecular Cell
Zeitschriftenartikel
22 (22), S. 3172 - 3177 (2021)
Structural basis of cyclic 1,3-diene forming acyl-coenzyme A dehydrogenases. Chembiochem
Zeitschriftenartikel
118 (46), e2107335118 (2021)
The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily. Proceedings of the National Academy of Sciences of the United States of America
Zeitschriftenartikel
7 (46), eabj3221 (2021)
High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism. Science Advances
Zeitschriftenartikel
7 (46), eabj5255 (2021)
Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state. Science Advances
Zeitschriftenartikel
22 (11), e52476 (2021)
A phosphatase-centric mechanism drives stress signaling response. EMBO Reports
Zeitschriftenartikel
595 (21), S. 2701 - 2714 (2021)
Cardiolipin prevents pore formation in phosphatidylglycerol bacterial membrane models. FEBS Letters
Zeitschriftenartikel
Sample Preparation by 3D-Correlative Focused Ion Beam Milling for High-Resolution Cryo-Electron Tomography. Journal of Visualized Experiments (176), e62886 (2021)
Zeitschriftenartikel
12 (1), 6127 (2021)
Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins. Nature Communications
Zeitschriftenartikel
1 (12), S. 2162 - 2171 (2021)
Solution Structure and Conformational Flexibility of a Polyketide Synthase Module. JACS Au
Zeitschriftenartikel
121 (19), S. 11701 - 11725 (2021)
Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems. Chemical Reviews
Zeitschriftenartikel
12 (1), 5934 (2021)
Simultaneous orientation and 3D localization microscopy with a Vortex point spread function. Nature Communications
Zeitschriftenartikel
60 (42), S. 23010 - 23017 (2021)
The voltage dependent sidedness of the reprotonation of the retinal Schiff base determines the unique inward pumping of Xenorhodopsin. Angewandte Chemie, International Edition in English
Zeitschriftenartikel
186, 105905 (2021)
Expression, purification and characterization of the IcmG and IcmK proteins of the Type IVB secretion system from Coxiella burnetii. Protein Expression and Purification
Zeitschriftenartikel
118 (37), e2113647118 (2021)
p62 condensates are a hub for proteasome-mediated protein turnover in the nucleus. Proceedings of the National Academy of Sciences of the United States of America
Zeitschriftenartikel
12 (1), 5364 (2021)
In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Nature Communications
Zeitschriftenartikel
22 (9), e52289 (2021)
Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control. EMBO Reports
Zeitschriftenartikel
373 (6559), S. 1151 - 1156 (2021)
Three-megadalton complex of methanogenic electron-bifurcating and CO2-fixing enzymes. Science
Zeitschriftenartikel
12 (1), 5236 (2021)
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Communications
Zeitschriftenartikel
6 (9), S. 1129 - 1139 (2021)
Structural and functional characterization of the intracellular filament-forming nitrite oxidoreductase multiprotein complex. Nature Microbiology
Zeitschriftenartikel
155 (8), 084503 (2021)
Kinetic pathways of water exchange in the first hydration shell of magnesium: Influence of water model and ionic force field. The Journal of Chemical Physics
Zeitschriftenartikel
36 (8), 109583 (2021)
Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling. Cell Reports
Zeitschriftenartikel
32 (17), S. 1523 - 1533 (2021)
Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex. Molecular Biology of the Cell
Zeitschriftenartikel
220 (8), e202011078 (2021)
Cysteine cross-linking in native membranes establishes the transmembrane architecture of Ire1. The Journal of Cell Biology
Zeitschriftenartikel
297 (2), 100925 (2021)
Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection. The Journal of Biological Chemistry
Zeitschriftenartikel
1862 (8), e148436 (2021)
Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms. Biochimica et Biophysica Acta, Bioenergetics
Zeitschriftenartikel
9 (8), 1636 (2021)
Polyhydroxyalkanoate (PHA) Production in Pseudomonas sp. phDV1 Strain Grown on Phenol as Carbon Sources. Microorganisms
Zeitschriftenartikel
DEER Spectroscopy of Channelrhodopsin-2 Helix B Movements in Trapped Photocycle Intermediates. Applied Magnetic Resonance (2021)
Zeitschriftenartikel
125 (28), S. 7732 - 7741 (2021)
Binding of SARS-CoV-2 Fusion Peptide to Host Endosome and Plasma Membrane. The Journal of Physical Chemistry B
Zeitschriftenartikel
60 (30), S. 16442 - 16447 (2021)
The Desensitized Channelrhodopsin-2 Photointermediate Contains 13 -cis, 15 -syn Retinal Schiff Base. Angewandte Chemie, International Edition in English
Zeitschriftenartikel
16 (7), e0253364 (2021)
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. PLoS One
Zeitschriftenartikel
28 (7), S. 1014 - 1031 (2021)
Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation. Cell Chemical Biology
Zeitschriftenartikel
11 (1), 13657 (2021)
A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments. Scientific Reports
Zeitschriftenartikel
4 (1), 821 (2021)
Structure-based insights into evolution of rhodopsins. Communications Biology
Zeitschriftenartikel
10, e70160 (2021)
Structure and mechanistic features of the prokaryotic minimal RNase P. eLife
Zeitschriftenartikel
154 (23), 234105 (2021)
Maximum likelihood estimates of diffusion coefficients from single-particle tracking experiments. The Journal of Chemical Physics
Zeitschriftenartikel
60 (24), S. 13323 - 13330 (2021)
The unusual homodimer of a heme‐copper terminal oxidase allows itself to utilize two electron donors. Angewandte Chemie, International Edition in English
Zeitschriftenartikel
7 (23), eabg0465 (2021)
Structure of the merozoite surface protein 1 from Plasmodium falciparum. Science Advances
Zeitschriftenartikel
33 (6), S. 2072 - 2091 (2021)
A ferredoxin bridge connects the two arms of plant mitochondrial complex I. The Plant Cell
Zeitschriftenartikel
118 (19), e2100425118 (2021)
Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America
Zeitschriftenartikel
118 (19), e2016974118 (2021)
Membrane fusion and drug delivery with carbon nanotube porins. Proceedings of the National Academy of Sciences of the United States of America
Zeitschriftenartikel
154 (17), 171102 (2021)
Extended magnesium and calcium force field parameters for accurate ion–nucleic acid interactions in biomolecular simulations. The Journal of Chemical Physics
Zeitschriftenartikel
16 (4), e0239881 (2021)
Refining pairwise sequence alignments of membrane proteins by the incorporation of anchors. plos one
Zeitschriftenartikel
7 (4), S. 514 - 523 (2021)
Molecular landscape of etioplast inner membranes in higher plants. Nature Plants
Zeitschriftenartikel
701, 108796 (2021)
Flavins in the electron bifurcation process. Archives of Biochemistry and Biophysics
Zeitschriftenartikel
17 (4), S. 2530 - 2540 (2021)
Optimized Magnesium Force Field Parameters for Biomolecular Simulations with Accurate Solvation, Ion-Binding, and Water-Exchange Properties. Journal of Chemical Theory and Computation
Zeitschriftenartikel
9, 680533 (2021)
Editorial: Integrating Timescales From Molecules Up. Frontiers in Chemistry
Zeitschriftenartikel
7, S. 524 - 538 (2021)
Structural insights into photosystem II assembly. Nature Plants
Zeitschriftenartikel
1862 (4), 148379 (2021)
Functional diversity of prokaryotic HdrA(BC) modules: Role in flavin-based electron bifurcation processes and beyond. Biochimica et Biophysica Acta, Bioenergetics
Zeitschriftenartikel
595 (7), S. 864 - 880 (2021)
The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways. FEBS Letters
Zeitschriftenartikel
17 (4), e1008790 (2021)
Computational epitope map of SARS-CoV-2 spike protein. PLoS Computational Biology
Zeitschriftenartikel
8, 636562 (2021)
Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders. Frontiers in Molecular Biosciences
Zeitschriftenartikel
26 (6), 1664 (2021)
PepFun: Open Source Protocols for Peptide-Related Computational Analysis. Molecules
Zeitschriftenartikel
7 (11), eabf4213 (2021)
Probing the photointermediates of light-driven sodium ion pump KR2 by DNP-enhanced solid-state NMR. Science Advances
Zeitschriftenartikel
54, e4 (2021)
Current limitations to high-resolution structure determination by single-particle cryoEM. Quarterly Reviews of Biophysics
Zeitschriftenartikel
213 (1), 107701 (2021)
Structure of the Yersinia injectisome in intracellular host cell phagosomes revealed by cryo FIB electron tomography. Journal of Structural Biology
Zeitschriftenartikel
288 (5), S. 1664 - 1678 (2021)
Structural and spectroscopic characterization of a HdrA‐like subunit from Hyphomicrobium denitrificans. The FEBS Journal
Zeitschriftenartikel
260, 107716 (2021)
PARCE: Protocol for Amino acid Refinement through Computational Evolution. Computer Physics Communications
Zeitschriftenartikel
8 (Pt 2), S. 186 - 194 (2021)
Devitrification reduces beam-induced movement in cryo-EM. IUCrJ
Zeitschriftenartikel
12 (7), S. 1926 - 1931 (2021)
FAM134B-RHD Protein Clustering Drives Spontaneous Budding of Asymmetric Membranes. The Journal of Physical Chemistry Letters
Zeitschriftenartikel
24 (2), 102021 (2021)
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening. iScience
Zeitschriftenartikel
184 (4), S. 1032 - 1046 (2021)
Cone-shaped HIV-1 capsids are transported through intact nuclear pores. Cell
Zeitschriftenartikel
12 (1), 1074 (2021)
Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers. Nature Communications
Zeitschriftenartikel
120 (3), S. 568 - 575 (2021)
Temperature Dependence of the Krokinobacter rhodopsin 2 Kinetics. Biophysical Journal (Annual Meeting Abstracts)
Zeitschriftenartikel
12, S. 93 - 101 (2021)
Fusion of purple membranes triggered by immobilization on carbon nanomembranes. Beilstein Journal of Nanotechnology
Zeitschriftenartikel
17 (1), S. 525 - 537 (2021)
Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model. Journal of Chemical Theory and Computation
Zeitschriftenartikel
11 (1), 618 (2021)
Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii. Scientific Reports
Zeitschriftenartikel
12 (1), 230 (2021)
Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution. Nature Communications
Zeitschriftenartikel
54, e2 (2021)
Setting up and operating a cryo-EM laboratory. Quarterly Reviews of Biophysics
Zeitschriftenartikel
20, 100016 (2021)
Proteome Turnover in the Spotlight: Approaches, Applications, and Perspectives. Molecular and Cellular Proteomics
Zeitschriftenartikel
28 (1), S. 2 - 7 (2021)
Structural biology in the fight against COVID-19. Nature Structural and Molecular Biology
Zeitschriftenartikel
17 (1), S. 1 - 382 (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy
Zeitschriftenartikel
21 (2), e2000003 (2021)
Proteomic Characterization of the Pseudomonas sp. Strain phDV1 Response to Monocyclic Aromatic Compounds. Proteomics
Zeitschriftenartikel
22 (2), 566 (2021)
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. International Journal of Molecular Sciences Buchkapitel (2)
2021
Buchkapitel
2191, S. 67 - 84. Springer Nature (2021)
Charge Transport by Light-Activated Rhodopsins Determined by Electrophysiological Recordings. In: Methods in Molecular Biology: Methods and Protocols - Channelrhodopsin, Bd.
Buchkapitel
2302, S. 153 - 178 (Hg. Schmidt-Krey, I.). Springer (2021)
Single-Particle Cryo-EM of Membrane Proteins. In: Methods in Molecular Biology: Structure and Function of Membrane Proteins, Bd. Hochschulschrift - Doktorarbeit (3)
2021
Hochschulschrift - Doktorarbeit
Electron cryo-tomography during the Resolution Revolution: a multi-scale study from protein denaturation to plant plastid bioenergetics. Dissertation, 158 S., Fachbereich Biochemie, Chemie und Pharmazie, Goethe Universität, Frankfurt am Main (2021)
Hochschulschrift - Doktorarbeit
Shaping and Remodeling of Biological Membranes. Dissertation, 180 S., Fachbereich Physik, Johann Wolfgang Goethe Universität, Frankfurt am Main (2021)
Hochschulschrift - Doktorarbeit
Molecular Simulation and Modeling of Chemically Modified Nucleic Acids. Dissertation, 174 S., Fachbereich Biochemie, Chemie und Pharmazie, Johann Wolfgang Goethe Universität, Frankfurt am Main (2021)
Hochschulschrift - Habilitation (1)
2021
Hochschulschrift - Habilitation
The Alpha and Omega of Biological Energy Conservation. Habilitation, 308 S., Fach Mikrobiologie, Fachbereich Biowissenschaften, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2021)
Hochschulschrift - Master (2)
2021
Hochschulschrift - Master
Structural and functional insights about the ABC Transporter CYDDC from E.coli. Master, 91 S., Department of Biochemistry, Chemistry and Pharmacy (FB 14), Johann Wolfgang Goethe University Frankfurt, Frankfurt am Main (2021)
Hochschulschrift - Master
Structure and Function of the Bacterial ABC Transporter CydDC. Master, 61 S., Departments of Biochemistry, Chemistry and Pharmacy, Goethe-University Frankfurt, Frankfurt am Main (2021)
Hochschulschrift - Bachelor (4)
2021
Hochschulschrift - Bachelor
How CHMP1b interacts with the membrane. Bachelor, 54 S., Fachbereich Physik, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2021)
Hochschulschrift - Bachelor
Herstellung, Reinigung und Charakterisierung universeller Anti-Nanobody Antikörper für die strukturbiologische Untersuchung. Bachelor, 62 S., Fachbereich Biowissenschaften, Johann Wolfgang Goethe-Universität, Frankfurt am Main (2021)
Hochschulschrift - Bachelor
Biochemical and Structural Characterization of Secondary Active Transporters using Nanobody Library. Bachelor, 42 S., Department of Biochemistry, Chemistry and Pharmacy, Johann Wolfgang Goethe University, Frankfurt am Main (2021)
Hochschulschrift - Bachelor
Development of a label free thermal shift assay to investigate the binding of small molecules to Escherichia coli bd-type oxidases. Bachelor, 68 S., Fakultät 2 Umwelt und Naturwissenschaften, Institut für Biotechnologie, Brandenburgische Technische Universität, Cottbus-Senftenberg, Germany (2021)