Publications of Thomas Friedrich

Geibel, S.; Lörinczi, E.; Bamberg, E.; Friedrich, T.: Voltage Dependence of Proton Pumping by Bacteriorhodopsin Mutants with Altered Lifetime of the M Intermediate. PLoS One 8 (9), p. e73338 - e73338 (2013)

Deng, H.; Yang, Z.; Li, Y.; Bao, G.; Friedrich, T.; Gu, Q.; Shen, X.; Schwarz, W.: Interactions of Na⁺,K⁺-ATPase and co-expressed δ-opioid receptor. Neuroscience Research 65 (3), pp. 222 - 227 (2009)

Lörinczi, E.; Verhoefen, M.-K.; Wachtveitl, J.; Woerner; Glaubitz, C.; Engelhard, M.; Bamberg, E.; Friedrich, T.: Voltage- and pH-Dependent Changes in Vectoriality of Photocurrents Mediated by Wild-type and Mutant Proteorhodopsins upon Expression in Xenopus Oocytes. Journal of Molecular Biology 393 (2), pp. 320 - 341 (2009)

Lörinczi, E.; Tsivkoskii, R.; Haase, W.; Bamberg, E.; Lutsenko, S.; Friedrich, T.: Delivery of the Cu-transporting ATPase ATP7B to the plasma membrane in Xenopus oocytes. Biochimica et Biophysica Acta: BBA 1778 (4), pp. 896 - 906 (2008)

Gorbunov, D.; Gorboulev, V.; Shatskaya, N.; Mueller, T.; Bamberg, E.; Friedrich, T.; Koepsell, H.: High-affinity Cation Binding to Organic Cation Transporter OCT1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modeled Interaction Domain between Two Helices. Molecular Pharmacology 73 (1), pp. 50 - 61 (2008)

Kalmbach, R.; Chizhov, I.; Schuhmacher, M. C.; Friedrich, T.; Bamberg, E.; Engelhard, M.: Functional Cell-free Synthesis of a Seven Helix Membrane Protein: In situ Insertion of Bacteriorhodopsin into Liposomes. Journal of Molecular Biology 371 (3), pp. 639 - 648 (2007)

Dempski, R. E.; Hartung, K.; Friedrich, T.; Bamberg, E.: Fluorometric Measurements of Intermolecular Distances between the α- and β-Subunits of the Na⁺/K⁺-ATPase. The Journal of Biological Chemistry 281 (47), pp. 36338 - 36346 (2006)

Schwake, M.; Athanasiadu, D.; Beimgraben, C.; Blanz, J.; Beck, C.; Saftig, P.; Friedrich, T.: Structural Determinants of M-Type KCNQ (K_v7) K⁺ Channel Assembly. The Journal of Neuroscience 26 (14), pp. 3757 - 3766 (2006)

Todt, U.; Dichgans, M.; Jurkat-Rott, K.; Heinze, A.; Zifarelli, G.; Koenderink, J. B.; Goebel, I.; Zumbroich, V.; Stiller, A.; Ramirez, A. et al.; Friedrich, T.; Göbel, H.; Kubisch, C.: Rare Missense Variants in ATP1A2 in Families With Clustering of Common Forms of Migraine. Human Mutations 26 (4), pp. 315 - 321 (2005)

Schenzer, A.; Friedrich, T.; Pusch, M.; Saftig, P.; Jentsch, T. J.; Grötzinger, J.; Schwake, M.: Molecular determinants of KCNQ (K_v7) K⁺ channel sensitivity to the anticonvulsant retigabine. The Journal of Neuroscience 25 (20), pp. 5051 - 5060 (2005)

Koenderink, J. B.; Zifarelli, G.; Yan Qiu, L.; Schwarz, W.; De Pont, J. J. H.H.M.; Bamberg, E.; Friedrich, T.: Na,K-ATPase mutations in familial hemiplegic migraine lead to functional inactivation. Biochimica et Biophysica Acta-Biomembranes 1669 (1), pp. 61 - 68 (2005)

Dempski, R. E.; Friedrich, T.; Bamberg, E.: The ß Subunit of the Na⁺/K⁺-ATPase Follows the Conformational State of the Holoenzyme. Journal of General Physiology 125 (5), pp. 505 - 520 (2005)

Koenderink, J. B.; Geibel, S.; Grabsch, E.; De Pont, J. J. H.H.M.; Bamberg, E.; Friedrich, T.: Electrophysiological analysis of the mutated Na,K-ATPase cation binding pocket. The Journal of Biological Chemistry 278 (51), pp. 51213 - 51222 (2003)

Geibel, S.; Zimmermann, D.; Zifarelli, G.; Becker, A.; Koenderink, J. B.; Hu, Y.-K.; Kaplan, J. H.; Friedrich, T.; Bamberg, E.: Conformational dynamics of Na⁺/K⁺- and H⁺/K⁺-ATPase probed by voltage clamp fluorometry. Annals of the New York Academy of Sciences 986 (1), pp. 31 - 38 (2003)

Koenderink, J. B.; Geibel, S.; Grabsch, E.; De Pont, J. J. H.H.M.; Bamberg, E.; Friedrich, T.: Two-electrode voltage-clamp analysis of Na,K-ATPase asparagine 776 mutants. Annals of the New York Academy of Sciences 986, pp. 150 - 154 (2003)

Geibel, S.; Kaplan, J. H.; Bamberg, E.; Friedrich, T.: Conformational dynamics of the Na⁺/K⁺-ATPase probed by voltage clamp fluorometry. Proceedings of the National Academy of Sciences of the United States of America 100 (3), pp. 964 - 969 (2003)

Friedrich, T.; Geibel, S.; Kalmbach, R.; Chizhov, I.; Ataka, K.; Heberle, J.; Engelhard, M.; Bamberg, E.: Proteorhodopsin is a light-driven proton pump with variable vectoriality. Journal of Molecular Biology (London) 321 (5), p. 821 - 821 (2002)

Geibel, S.; Friedrich, T.; Ormos, P.; Wood, P. G.; Nagel, G.; Bamberg, E.: The Voltage Dependent Proton Pumping in Bacteriorhodopsin Is Characterized by Optoelectric Behavior. Biophysical Journal 81 (4), p. 2059-2068 (2001)

Pusch, M.; Ferrera, L.; Friedrich, T.: Two open states and rate-limiting gating steps revealed by intracellular Na⁺ block of human KCNQ1 and KCNQ1/KCNE1 K⁺ channels. Journal of Physiology 533 (1), pp. 135 - 143 (2001)

Nagel, G.; Szellas, T.; Riordan, J. R.; Friedrich, T.; Hartung, K.: Non-specific activation of the epithelial sodium channel by the CFTR chloride channel. EMBO Reports 2 (3), pp. 249 - 254 (2001)

Nagel, G.; Volk, C.; Friedrich, T.; Ulzheimer, J. C.; Bamberg, E.; Koepsell, H.: A Reevaluation of Substrate Specificity of the Rat Cation Transporter rOCT1. The Journal of Biological Chemistry 272 (51), pp. 31953 - 31956 (1997)

Friedrich, T.; Nagel, G.: Comparison of Na⁺/K⁺-ATPase pump currents activated by ATP concentration or voltage jumps. Biophysical Journal 73 (1), pp. 186 - 194 (1997)

Niu, L.; Vazquez, R.; Nagel, G.; Friedrich, T.; Bamberg, E.; Oswald, R. E.; Hess, G. P.: Rapid chemical kinetic techniques for investigations of neurotransmitter receptors expressed in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America 93 (23), pp. 12964 - 12968 (1996)

Friedrich, T.; Bamberg, E.; Nagel, G.: Na⁺,K⁺-ATPase pump currents in giant excised patches activated by an ATP concentration jump. Biophysical Journal 71 (5), pp. 2486 - 2500 (1996)

Friedrich, T.; Burckhardt, G.: Inhibition and labeling of the rat renal Na⁺/H⁺-exchanger by an antagonist of muscarinic acetylcholine receptors. Biochemical and Biophysical Research Communications 157 (3), pp. 921 - 929 (1988)

Geys, S.; Zifarelli, G.; Bamberg, E.; Friedrich, T.: The Influence of Intracellular Na⁺ on the E₁P–E₂P Conformational Change of the Na,K-ATPase Probed by Voltage-clamp Fluorometry. 59th Annual Meeting of the Society of General Physiologists, Marine Biological Laboratory, Woods Hole Massachusetts (2005)

Zifarelli, G.; Geibel, S.; Bamberg, E.; Friedrich, T.: Influence of cations on the E₁P-E₂P conformational change of the Na,K-ATPase probed by voltage clamp fluorometry. 47th Annual Meeting , Henry B. Gonzalez Convention Center, San Antonio, Texas, USA (2003)

Friedrich, T.: Untersuchung von stationären und transienten Strömen der Na⁺/K⁺-ATPase mittels der giant-patch Technik. Dissertation, 175 pp., Fachbereich Biochemie, Pharmazie, Lebensmittelchemie, Johann Wolfgang Goethe-Universität, Frankfurt am Main (1996)

Friedrich, T.: Untersuchungen zu Mechanismus und Regulation des aktiven und passiven Ionentransports durch Membranproteine. Habilitation, Johann Wolfgang Goethe-Universtität, Frankfurt am Main (2004)