
Publications of Klaus Fendler
All genres
Journal Article (82)
2022
Journal Article
298 (2), 101505 (2022)
Investigation of sugar binding kinetics of the E. coli sugar/H+ symporter XylE using solid-supported membrane-based electrophysiology. The Journal of Biological Chemistry 2019
Journal Article
151 (12), pp. 1357 - 1368 (2019)
A channel profile report of the unusual K+ channel KtrB. Journal of General Physiology
Journal Article
9, 15390 (2019)
Mutation of two key aspartate residues alters stoichiometry of the NhaB Na+/H+ exchanger from Klebsiella pneumoniae. Scientific Reports
Journal Article
58, pp. 62 - 71 (2019)
Coupling efficiency of secondary active transporters. Current Opinion in Biotechnology
Journal Article
294 (1), pp. 246 - 256 (2019)
Replacement of Lys-300 with a glutamine in the NhaA Na+/H+ antiporter of Escherichia coli yields a functional electrogenic transporter. The Journal of Biological Chemistry 2017
Journal Article
113 (12), pp. 2736 - 2749 (2017)
Loose Relationship: Incomplete H+/Sugar Coupling in the MFS Sugar Transporter GlcP. Biophysical Journal
Journal Article
113 (6), pp. 1331 - 1341 (2017)
From Gene to Function: Cell-Free Electrophysiological and Optical Analysis of Ion Pumps in Nanodiscs. Biophysical Journal
Journal Article
12 (7), e0182293 (2017)
Competition is the basis of the transport mechanism of the NhaB Na+/H+ exchanger from Klebsiella pneumoniae. PLoS One
Journal Article
292 (19), pp. 7932 - 7941 (2017)
Lysine 300 is essential for stability but not for electrogenic transport of the Escherichia coli NhaA Na+/H+ antiporter. The Journal of Biological Chemistry 2016
Journal Article
291 (52), pp. 26786 - 26793 (2016)
Electrogenic Cation Binding in the Electroneutral Na+/H+ Antiporter of Pyrococcus abyssi. The Journal of Biological Chemistry
Journal Article
11 (5), e0156392 (2016)
pH Regulation of Electrogenic Sugar/H+ Symport in MFS Sugar Permeases. PLoS One
Journal Article
1858 (4), pp. 698 - 705 (2016)
Functional characterization of solute carrier (SLC) 26/sulfate permease (SulP) proteins in membrane mimetic systems. Biochimica et Biophysica Acta-Biomembranes 2015
Journal Article
396 (9-10), pp. 1091 - 1096 (2015)
A universal mechanism for transport and regulation of CPA sodium proton exchangers. Biological Chemistry 2014
Journal Article
588 (17), pp. 3111 - 3116 (2014)
Species differences in bacterial NhaA Na+/H+ exchangers. FEBS Letters
Journal Article
9 (7), pp. 1 - 8 (2014)
Molecular Characterization of the Na+H+-Antiporter NhaA from Salmonella Typhimurium. PLoS One
Journal Article
289, pp. 13168 - 13176 (2014)
Keeping It Simple, Transport Mechanism and pH Regulation in Na+/H+. The Journal of Biological Chemistry
Journal Article
9 (4), p. e93200 - e93200 (2014)
NhaA Na+/H+ Antiporter Mutants That Hardly React to the Membrane Potential. PLoS One 2013
Journal Article
52 (46), pp. 8261 - 8266 (2013)
Electrophysiological Characterization of Uncoupled Mutants of LacY. Biochemistry
Journal Article
288 (34), pp. 24666 - 24675 (2013)
Differential Effects of Mutations on the Transport Properties of the Na+/H+ Antiporter NhaA from Escherichia coli. The Journal of Biological Chemistry
Journal Article
75, e50230 (2013)
Introduction to Solid Supported Membrane Based Electrophysiology. Journal of Visualized Experiments
Journal Article
42, pp. 95 - 120 (2013)
Electrophysiological Characterization of Membrane Transport Proteins. Annual Review of Biophysics 2012
Journal Article
109 (44), pp. E3035 - E3045 (2012)
Investigation of the sodium binding sites in the betaine transporter BetP. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
1818 (5), pp. 1342 - 1350 (2012)
The nitrite transport protein NirC from Salmonella typhimurium is a nitrite/proton antiporter. Biochimica et Biophysica Acta-Biomembranes 2011
Journal Article
1808 (10), pp. 2508 - 2516 (2011)
G117C MelB, a mutant melibiose permease with a changed conformational equilibrium. Biochimica et Biophysica Acta-Biomembranes
Journal Article
286 (26), pp. 23570 - 23581 (2011)
Transport mechanism and pH regulation of the Na+/H+ antiporter NhaA from Escherichia coli: An electrophysiological study. Journal of Biological Chemistry
Journal Article
64 (1), pp. 31 - 35 (2011)
Robust Electrophysiological Assays using Solid Supported Membranes: the Organic Cation Transporter OCT2. Australian Journal of Chemistry 2010
Journal Article
5 (9), e12585 (2010)
The G215R Mutation in the Cl-/H+-Antiporter ClC-7 Found in ADO II Osteopetrosis Does Not Abolish Function but Causes a Severe Trafficking Defect. PLoS One
Journal Article
49 (29), pp. 6115 - 6121 (2010)
Delineating Electrogenic Reactions during Lactose/H+ Symport. Biochemistry 2009
Journal Article
97 (1), pp. 388 - 396 (2009)
Measuring Ion Channels on Solid Supported Membranes. Biophysical Journal
Journal Article
1781, pp. 706 - 713 (2009)
Bacterial transporters: Charge translocation and mechanism. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
106 (18), pp. 7373 - 7378 (2009)
Electrophysiological characterization of LacY. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
177 (1), pp. 131 - 141 (2009)
An automatic electrophysiological assay for the neuronal glutamate transporter mEAAC1. Journal of Neuroscience Methods 2008
Journal Article
46, pp. 97 - 103 (2008)
SSM-based electrophysiology. Methods
Journal Article
24, pp. 8119 - 8126 (2008)
Rapid Activation of the Melibiose Permease MelB Immobilized on a Solid-Supported Membrane. Langmuir
Journal Article
476, pp. 75 - 86 (2008)
Charge transfer in P-type ATPases investigated on planar membranes. Archives of Biochemistry and Biophysics 2007
Journal Article
46 (48), pp. 13920 - 13928 (2007)
The Conserved Dipole in Transmembrane Helix 5 of KdpB in the Escherichia coli KdpFABC P-Type ATPase Is Crucial for Coupling and the Electrogenic K+-Translocation Step. Biochemistry
Journal Article
23 (20), pp. 10074 - 10080 (2007)
Specific Anion and Cation Binding to Lipid Membranes Investigated on a Solid Supported Membrane. Langmuir 2006
Journal Article
36, pp. 25882 - 25892 (2006)
The inner interhelix loop 4-5 of the melibiose permease from Escherichia coli takes part in conformational changes after sugar binding. The Journal of Biological Chemistry
Journal Article
4 (5), pp. 575 - 582 (2006)
Transporter Assays Using Solid Supported Membranes: A Novel Screening Platform for Drug Discovery. Assay and Drug Development Technologies
Journal Article
45, pp. 12796 - 12805 (2006)
Structure and Function of Prokaryotic Glutamate Transporters from Escherichia coli and Pyrococcus horikoshii. Biochemistry 2005
Journal Article
272 (23), pp. 6024 - 6038 (2005)
Evaluation of detergents for the soluble expression of α-helical and β-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system. The FEBS Journal
Journal Article
1709 (3), pp. 240 - 250 (2005)
Kinetics of charge translocation in the passive downhill uptake mode of the Na+/H+ antiporter NhaA of Escherichia coli. Biochimica et Biophysica Acta, Bioenergetics 2004
Journal Article
43, pp. 12606 - 12613 (2004)
Sugar Binding Induced Charge Translocation in the Melibiose Permease from Escherichia coli. Biochemistry
Journal Article
343, pp. 931 - 942 (2004)
Charge Translocation During Cosubstrate Binding in the Na+/Proline Transporter of E. coli. Journal of Molecular Biology 2003
Journal Article
85 (3), pp. 2044 - 2054 (2003)
Charge displacements during ATP-hydrolysis and synthesis of the Na+ -transporting FoF1-ATPase of Ilyobacter tartaricus. Biophysical Journal 2002
Journal Article
417 (6884), pp. 99 - 102 (2002)
Reduction of cytochrome c oxidase by a second electron leads to proton translocation. Nature 2001
Journal Article
40 (45), pp. 13744 - 13752 (2001)
Evidence for Intraprotein Charge Transfer during the Transport Activity of the Melibiose Permease from Escherichia Coli. Biochemistry
Journal Article
81 (5), pp. 2628 - 2638 (2001)
Voltage and Ca2+ Dependence of Pre–Steady-State Currents of the Na-Ca Exchanger Generated by Ca2+ Concentration Jumps. Biophysical Journal
Journal Article
33 (5), pp. 401 - 405 (2001)
Electrogenic properties of the Na+,K+-ATPase probed by presteady state and relaxation studies. Journal of Bioenergetics and Biomembranes 2000
Journal Article
79 (5), pp. 2557 - 2571 (2000)
Na+ Transport, and the E1P-E2P Conformational Transition of the Na+/K+-ATPase. Biophysical Journal
Journal Article
79 (3), pp. 1346 - 1357 (2000)
P3[2-(4-hydroxyphenyl)-2-oxo]ehtyl ATP for the Rapid Activation of the Na+, K+-ATPase. Biophysical Journal
Journal Article
79 (2), pp. 802 - 813 (2000)
Replacement of Glycine 232 by Aspartic Acid in the KdpA Subunit Broadens the Ion Specificity of the K+-translocating KdpFABC Complex. Biophysical Journal
Journal Article
97 (9), pp. 4632 - 4636 (2000)
Single-electron reduction of the oxidized state is coupled to proton uptake via the K pathway in Paracoccus denitrificans cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America 1999
Journal Article
274 (53), pp. 37974 - 37981 (1999)
Mutation of Arg-54 Strongly Influences Heme Composition and Rate and Directionality of Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase. The Journal of Biological Chemistry
Journal Article
14 (7), pp. 651 - 662 (1999)
The peptide-tethered lipid membrane as a biomimetic system to incorporate cytochrome c oxidase in a functionally active form. Biosensors and Bioelectronics
Journal Article
77 (2), p. 714-726 - 714-726 (1999)
Kinetics of electrogenic transport by the ADP/ATP carrier. Biophysical Journal
Journal Article
77 (1), pp. 267 - 281 (1999)
Hofmeister Effects of Anions on the Kinetics of Partial Reactions of the Na+,K+-ATPase. Biophysical Journal
Journal Article
38 (6), pp. 1850 - 1856 (1999)
The Kdp-ATPase of Escherichia coli mediates an ATP-dependent, K+-independent electrogenic partial reaction. Biochemistry
Journal Article
76 (2), pp. 814 - 826 (1999)
Charge Translocation by the Na+/K+-ATPase Investigated on Solid Supported Membranes: Rapid Solution Exchange with a New Technique. Biophysical Journal
Journal Article
76 (2), pp. 827 - 836 (1999)
Charge Translocation by the Na+/K+-ATPase Investigated on Solid Supported Membranes: Cytoplasmic Cation Binding and Release. Biophysical Journal 1998
Journal Article
163, pp. 137 - 146 (1998)
Structure and Function of the Kdp-ATPase of Escherichia Coli. Acta Physiologica Scandinavica
Journal Article
1368 (2), pp. 184 - 200 (1998)
K+-dependence of electrogenic transport by the NaK-ATPase. Biochimica et Biophysica Acta-Biomembranes 1997
Journal Article
834 (1), pp. 361 - 363 (1997)
Electrogenic Reactions of Na+/K+‐ATPase Investigated on Solid Supported Membranes. Annals of the New York Academy of Sciences
Journal Article
36 (43), pp. 13406 - 13420 (1997)
Stopped-Flow Kinetic Investigations of Conformational Changes of Pig Kidney Na+,K+-ATPase. Biochemistry
Journal Article
72 (6), pp. 2503 - 2514 (1997)
Time-resolved charge translocation by the Ca-ATPase from sarcoplasmic reticulum after an ATP concentration jump. Biophysical Journal 1996
Journal Article
35 (24), pp. 8009 - 8017 (1996)
Electrogenic K+ Transport by the Kdp-ATPase of Escherichia coli. Biochemistry 1993
Journal Article
102 (4), pp. 631 - 666 (1993)
Pre-steady-state charge translocation in NaK-ATPase from eel electric organ. Journal of General Physiology
Journal Article
90 (8), pp. 3578 - 3582 (1993)
Bacteriorhodopsin expressed in Schizosaccharomyces pombe pumps protons through the plasma membrane. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
132, pp. 211 - 227 (1993)
Kinetics of Transient Pump Currents Generated by the (H,K)-ATPase after an ATP Concentration Jump. Journal of Membrane Biology
Journal Article
26 (1), pp. 1 - 25 (1993)
Charge transport of ion pumps on lipid bilayer membranes. Quarterly Reviews of Biophysics
Journal Article
64 (2), pp. 384 - 391 (1993)
Charge transport by ion translocating membrane proteins on solid supported membranes. Biophysical Journal
Journal Article
169 (1), pp. 75 - 84 (1993)
Scan speed limit in atomic force microscopy. Journal of Microscopy 1992
Journal Article
671 (1), pp. 170 - 188 (1992)
Charge translocation of H,K-ATPase and Na,K-ATPase. Annals of the New York Academy of Sciences 1991
Journal Article
19, pp. 241 - 251 (1991)
The reaction cycle of Bacteriorhodopsin: An analysis using visible absorption, photocurrent and infrared techniques. European Biophysics Journal 1989
Journal Article
56 (5), pp. 851 - 859 (1989)
Temperature jump study of charge translocation during the bacteriorhodopsin photocycle. Biophysical Journal
Journal Article
8 (3), pp. 377 - 379 (1989)
Charge translocation by the sarcoplasmic Ca ATPase after an ATP concentration jump. Journal of Protein Chemistry
Journal Article
8 (6), pp. 1657 - 1663 (1989)
Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump. EMBO Journal 1987
Journal Article
224 (1), pp. 83 - 88 (1987)
Kinetics of pump currents generated by the Na+,K+-ATPase. FEBS Letters
Journal Article
893 (1), pp. 60 - 68 (1987)
Electrogenic transport properties of bacteriorhodopsin containing chemically modified retinal analogues. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
901 (2), pp. 239 - 249 (1987)
Na+ currents generated by the purified Na+K+-ATPase on planar lipid membranes. Biochimica et Biophysica Acta-Biomembranes 1985
Journal Article
4 (12), pp. 3079 - 3085 (1985)
Pump currents generated by the purified Na+K+-ATPase from kidney on black lipid membranes. The EMBO Journal
Journal Article
187 (2), pp. 233 - 236 (1985)
Primary charge separation in halorhodopsin. FEBS Letters Book Chapter (6)
2017
Book Chapter
594, pp. 31 - 83 (Ed. Ziegler, C.). Academic Press, Cambridge, MA 02139, USA (2017)
Chapter Two - SSM-Based Electrophysiology for Transporter Research. In: Methods in Enzymology, Vol. 2015
Book Chapter
183, pp. 147 - 177 (Eds. Clarke, R. J.; Khalid, M. A. A.). John Wiley & Sons, Hoboken, New Jersey (2015)
Recording of Pump and Transporter Activity using Solid-Supported Membranes (SSM-based electrophysiology). In: Pumps, Channels and Transporters: Methods of Functional Analysis (Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications), Vol.
Book Chapter
556, pp. 475 - 497 (Ed. Shukla, A. K.). Elsevier Inc., Amsterdam (2015)
Structural and functional studies of NirC from Salmonella typhimurium. In: Methods in Enzymology, Vol. 2004
Book Chapter
2, pp. 331 - 349 (Ed. Vladimir M., V. M.). Springer-Verlag, Berlin, Heidelberg (2004)
Transport Proteins on Solid-Supported Membranes: From Basic Research to Drug Discovery. In: Springer Series on Chemical Sensors and Biosensors (Methods and Applications), Vol. 1998
Book Chapter
291, pp. 289 - 306 (Ed. Marriott, G.). Academic Press (1998)
Investigation of charge translocation by ion pumps and carriers using caged substrates. In: Methods in Enzymology, Vol. 1994
Book Chapter
Bamberg, E.; Schoner, W.). Steinkopff Verlag GmbH & Co. KG, Darmstadt 1994, Darmstadt, Germany (1994)
Electrogenic and electroneutral partial reactions in Na+/K+ ATPase from eel electric organ. In: The Sodium Pump, pp. 495 - 506 (Eds. Conference Paper (4)
1991
Conference Paper
46 Part 1, pp. 227 - 247 (Eds. Kaplan, J. H.; De Weer, P.). 6th International Conference on the Sodium Pump , Woods Hole, Massachusetts, USA, September 05, 1990 - September 09, 1990. The Rockefeller University Press, New York (1991)
The partial reactions of the Na+- and Na+ + K+-activated adenosine triphosphatases. In: The Sodium Pump: Structure, Mechanism, and Regulation, Vol. 1988
Conference Paper
273, pp. 225 - 232 (1988)
Pump Currents Generated by Renal Na+K+-ATPase on Black Lipid Membranes. Proceedings of the First Shoresh Workshop on Ion Pumps, Shoresh, Israel, August 30, 1987 - September 02, 1987. Progress in Clinical and Biological Research
Conference Paper
268A, pp. 501 - 510 (1988)
Pump Currents Generated by Renal Na+K+-ATPase and Gastric H+K+-ATPase on Black Lipid Membranes. Proceedings of the 5th International Conference on Na+K+-ATPase, Fuglsø Conference Center, Denmark, June 14, 1987 - June 19, 1987. Progress in Clinical and Biological Research 1987
Conference Paper
Electrical properties of the light driven Cl- pump halorhodopsin. In: Retinal Proteins, pp. 363 - 379 (Ed. Ovchinnikov, Y.A.). Proceedings of an International Conference on Retinal Proteins, Irkutsk, (Lake Baikal) USSR, July 22, 1986 - July 28, 1986. VNU Science Press, Utrecht, The Netherlands (1987)
Conference Report (1)
1991
Conference Report
46 Part 2, pp. 525 - 530 (Eds. Kaplan, J. H.; De Weer, P.). 6th International Conference on the Sodium Pump, Woods Hole, Massachusetts, USA, September 05, 1990 - September 09, 1990. The Rockefeller University Press, New York (1991)
Correlation of Charge Translocation with the Reaction Cycle of the NaK-ATPase. In: The Sodium Pump: Recent Developments, Vol. Thesis - Habilitation (1)
1995
Thesis - Habilitation
Elektrogene Schritte im Reaktionszyklus von NaK- und HK-ATPase. Habilitation, 126 pp., Fachbereich Biochemie, Pharmazie und Lebensmittelchemie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (1995)