Publications of the Max Planck Institute of Biophysics 1947 – present
Journal Article (78)
2017
Journal Article
6, 10.7554/eLife.30483 (2017)
Cryo-EM structure of the bifunctional secretin complex of Thermus thermophilus. eLife
Journal Article
13 (12), pp. 6328 - 6342 (2017)
Dynamic Histogram Analysis To Determine Free Energies and Rates from Biased Simulations. Journal of Chemical Theory and Computation
Journal Article
6, e33274 (2017)
Structural basis of proton translocation and force generation in mitochondrial ATP synthase. eLife
Journal Article
35 (12), pp. 1196 - 1201 (2017)
Cell-type-specific metabolic labeling of nascent proteomes in vivo. Nature Biotechnology
Journal Article
113 (12), pp. 2736 - 2749 (2017)
Loose Relationship: Incomplete H+/Sugar Coupling in the MFS Sugar Transporter GlcP. Biophysical Journal
Journal Article
73 (12), pp. 997 - 1006 (2017)
A standardized technique for high-pressure cooling of protein crystals. Acta Crystallographica. Section D: Biological Crystallography (Copenhagen)
Journal Article
8, 1607 (2017)
DM9 Domain Containing Protein Functions As a Pattern Recognition Receptor with Broad Microbial Recognition Spectrum. Frontiers in immunology
Journal Article
57 (11), pp. 2833 - 2845 (2017)
Classical Molecular Dynamics with Mobile Protons. Journal of Chemical Information and Modeling
Journal Article
358 (6366), eaan8862, p. 1018 (2017)
Structural insights into ion conduction by channelrhodopsin 2. Science
Journal Article
8, 1577 (2017)
The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile. Nature Communications
Journal Article
25 (11), pp. 2546 - 2560 (2017)
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina. Molecular Therapy
Journal Article
41 (6), pp. 828 - 853 (2017)
Functional insights into pathogen biology from 3D electron microscopy. FEMS Microbiology Reviews
Journal Article
2, pp. 1507 - 1512 (2017)
Cryo-EM structure of the extended type VI secretion system sheath–tube complex. Nature Microbiology
Journal Article
85 (11), pp. 2017 - 2023 (2017)
A rare polyglycine type II-like helix motif in naturally occurring proteins. Proteins: Structure, Function, and Bioinformatics
Journal Article
114 (44), pp. 11691 - 11696 (2017)
Ligand-induced conformational dynamics of the Escherichia coli Na+/H+ antiporter NhaA revealed by hydrogen/deuterium exchange mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
7, 14450 (2017)
On-demand optogenetic activation of human stem-cell-derived neurons. Scientific Reports
Journal Article
13 (10), e1005817 (2017)
Scaffolding the cup-shaped double membrane in autophagy. PLoS Computational Biology
Journal Article
147 (15), 152716 (2017)
Transition path sampling of rare events by shooting from the top. The Journal of Chemical Physics
Journal Article
147 (15), 152725 (2017)
Peptide dimerization-dissociation rates from replica exchange molecular dynamics. The Journal of Chemical Physics
Journal Article
19 (10), pp. 3930 - 3937 (2017)
Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress. Environmental Microbiology
Journal Article
7 (3), 031060 (2017)
Variational Identification of Markovian Transition States. Physical Review X
Journal Article
11 (9), pp. 9558 - 9565 (2017)
Formation and Stability of Lipid Membrane Nanotubes. ACS Nano
Journal Article
3 (9), e1603187 (2017)
Inward H+ pump xenorhodopsin: Mechanism and alternative optogenetic approach. Science Advances
Journal Article
16, 157 (2017)
Pseudomonas stutzeri as an alternative host for membrane proteins. Microbial Cell Factories
Journal Article
113 (6), pp. 1331 - 1341 (2017)
From Gene to Function: Cell-Free Electrophysiological and Optical Analysis of Ion Pumps in Nanodiscs. Biophysical Journal
Journal Article
112 (37), pp. 11571 - 11576 (2017)
Redox-induced activation of the proton pump in the respiratory complex I. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
8, 542 (2017)
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nature Communications
Journal Article
139 (34), pp. 11674 - 11677 (2017)
Resolving the Conformational Dynamics of DNA with Ångstrom Resolution by Pulsed Electron–Electron Double Resonance and Molecular Dynamics. Journal of the American Chemical Society
Journal Article
56 (36), pp. 10806 - 10809 (2017)
A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angewandte Chemie, International Edition in English
Journal Article
357 (6352), pp. 699 - 703 (2017)
Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science
Journal Article
67 (4), pp. 673 - 684 (2017)
Activation of the Unfolded Protein Response by Lipid Bilayer Stress. Molecular Cell
Journal Article
170 (4), pp. 693 - 700 (2017)
Cryo-EM Structure of the TOM Core Complex from Neurospora crassa. Cell
Journal Article
13 (8), pp. 3927 - 3935 (2017)
Kinetics from Replica Exchange Molecular Dynamics Simulations. Journal of Chemical Theory and Computation
Journal Article
12 (7), e0182293 (2017)
Competition is the basis of the transport mechanism of the NhaB Na+/H+ exchanger from Klebsiella pneumoniae. PLoS One
Journal Article
216 (9), pp. 2715 - 2729 (2017)
MEIS homeodomain proteins facilitate PARP1/ARTD1-mediated eviction of histone H1. The Journal of Cell Biology: JCB
Journal Article
6, e24662 (2017)
Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. eLife
Journal Article
114 (28), pp. E5494 - E5503 (2017)
Intrinsic map dynamics exploration for uncharted effective free-energy landscapes. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
6, e27470 (2017)
Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery. eLife
Journal Article
198 (37), pp. 37 - 58 (2017)
Towards artificial methanogenesis: biosynthesis of the [Fe]-hydrogenase cofactor and characterization of the semi-synthetic hydrogenase. Faraday Discussions
Journal Article
292 (19), pp. 7932 - 7941 (2017)
Lysine 300 is essential for stability but not for electrogenic transport of the Escherichia coli NhaA Na+/H+ antiporter. The Journal of Biological Chemistry
Journal Article
93 (3), pp. 782 - 795 (2017)
Photochemical Properties of the Red-shifted Channelrhodopsin Chrimson. Photochemistry and Photobiology
Journal Article
6, e23471 (2017)
Modeling Hsp70/Hsp40 interaction by multi-scale molecular simulations and coevolutionary sequence analysis. eLife
Journal Article
13 (6), pp. 2962 - 2976 (2017)
Position-Dependent Diffusion Tensors in Anisotropic Media from Simulation: Oxygen Transport in and through Membranes. Journal of Chemical Theory and Computation
Journal Article
85 (5), pp. 812 - 826 (2017)
Systematic evaluation of CS‐Rosetta for membrane protein structure prediction with sparse NOE restraints. Proteins: Structure, Function, and Bioinformatics
Journal Article
121 (15), pp. 3331 - 3339 (2017)
Dynamics of the Orientational Factor in Fluorescence Resonance Energy Transfer. The Journal of Physical Chemistry B
Journal Article
18 (8), pp. 942 - 948 (2017)
Molecule Counts in Localization Microscopy with Organic Fluorophores. ChemPhysChem
Journal Article
429 (6), pp. 911 - 921 (2017)
Optogenetic Control of Ca2+ and Voltage-Dependent Large Conductance (BK) Potassium Channels. Journal of Molecular Biology (London)
Journal Article
6, e23644 (2017)
CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin. eLife
Journal Article
1858 (3), pp. 231 - 238 (2017)
Subunit CcoQ is involved in the assembly of the Cbb3-type cytochrome c oxidases from Pseudomonas stutzeri ZoBell but not required for their activity. Biochimica et Biophysica Acta, Bioenergetics
Journal Article
11 (2), pp. 1273 - 1280 (2017)
Carbon Nanotubes Mediate Fusion of Lipid Vesicles. ACS Nano
Journal Article
121 (7), pp. 1525 - 1530 (2017)
Equivalence of M- and P-Summation in Calculations of Ionic Solvation Free Energies. The Journal of Physical Chemistry A
Journal Article
121 (4), pp. 671 - 682 (2017)
From Aβ Filament to Fibril: Molecular Mechanism of Surface-Activated Secondary Nucleation from All-Atom MD Simulations. The Journal of Physical Chemistry B
Journal Article
197 (2), pp. 135 - 144 (2017)
Dynamo Catalogue: Geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms. Journal of Structural Biology
Journal Article
50 (1), pp. 327 - 330 (2017)
MPI tray: a versatile crystallization plate for membrane proteins. Journal of Applied Crystallography
Journal Article
114 (4), pp. E438 - E447 (2017)
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
56 (4), pp. 1146 - 1151 (2017)
The Crystal Structure of RosB: Insights into the Reaction Mechanism of the First Member of a Family of Flavodoxin-like Enzymes. Angewandte Chemie, International Edition in English
Journal Article
7, 39674 (2017)
Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Scientific Reports
Journal Article
12 (1), e0169506 (2017)
Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures. PLoS One
Journal Article
551, pp. 525 - 528 (2017)
Structure of the human MHC-I peptide-loading complex. Nature
Journal Article
7, 15653, pp. 1 - 16 (2017)
The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria. Scientific Reports
Journal Article
210 (01), pp. 163 - 171 (2017)
BioEM: GPU-accelerated computing of Bayesian inference of electron microscopy images. Computer Physics Communications
Journal Article
Helical jackknives control the gates of the double-pore K+ uptake system KtrABs. eLife, pp. 1 - 21 (2017)
Journal Article
18, pp. 1786 - 1800 (2017)
Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo‐tomography. EMBO Reports
Journal Article
12, pp. 106 - 119 (2017)
Structural Simplification of Bedaquiline: the Discovery of 3-(4-(N,N-Dimethylaminomethyl)phenyl)quinoline-Derived Antitubercular Lead Compounds. ChemMedChem
Journal Article
25 (12), pp. 1809 - 1819 (2017)
Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin. Structure
Journal Article
429 (19), pp. 2907 - 2917 (2017)
Hidden Twins: SorCS Neuroreceptors Form Stable Dimers. Journal of Molecular Biology (London)
Journal Article
356, pp. 194 - 197 (2017)
Architecture of a transcribing-translating expressome. Science
Journal Article
45 (11), pp. 6945 - 6959 (2017)
RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Research
Journal Article
114 (5), pp. 992 - 997 (2017)
In situ structure of trypanosomal ATP synthase dimer reveals a unique arrangement of catalytic subunits. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
420, pp. 70 - 76 (2017)
Controlled growth of periodically aligned copper-silicide nanocrystal arrays on silicon directed by laser-induced periodic surface structures (LIPSS). Applied Surface Science
Journal Article
56 (44), pp. 13893 - 13897 (2017)
Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase. Angewandte Chemie, International Edition in English
Journal Article
8, 2073, p. 1 (2017)
Structure of outer membrane protein G in lipid bilayers. Nature Communications
Journal Article
11 (6), pp. 6467 - 6473 (2017)
Self-Perforated Hydrogel Nanomembranes Facilitate Structural Analysis of Proteins by Electron Cryo-Microscopy. ACS Nano
Journal Article
18 (6), pp. 1 - 10 (2017)
Molecular architecture of the N‐type ATPase rotor ring from Burkholderia pseudomallei. EMBO Reports
Journal Article
41, pp. 299 - 314 (2017)
The PomXYZ Proteins Self-Organize on the Bacterial Nucleoid to Stimulate Cell Division. Developmental Cell
Journal Article
46, pp. 48 - 54 (2017)
Advances in high-resolution cryo-EM of oligomeric enzymes. Current Opinion in Structural Biology
Journal Article
3 (2), pp. 152 - 161 (2017)
Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors. ACS Infect. Dis.
Journal Article
24 (2), pp. 123 - 130 (2017)
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2. Nature Structural and Molecular Biology Book Chapter (3)
2017
Book Chapter
Catabolic Pathways and Enzymes Involved in Anaerobic Methane Oxidation. In: Handbook of Hydrocarbon and Lipid Microbiology, pp. 1 - 29. Springer International Publishing AG 2017, 6330 Cham Switzerland (2017)
Book Chapter
594, pp. 31 - 83 (Ed. Ziegler, C.). Academic Press, Cambridge, MA 02139, USA (2017)
Chapter Two - SSM-Based Electrophysiology for Transporter Research. In: Methods in Enzymology, Vol.
Book Chapter
1567, pp. 315 - 336. Humana Press, New York (2017)
Analysis of Mitochondrial Membrane Protein Complexes by Electron Cryo-tomography. In: Mitochondria. Methods in Molecular Biology (MIMB), Vol. Conference Paper (1)
2017
Conference Paper
10071, 100710K. SPIE BiOS, 2017, San Francisco, California, United States, January 28, 2017 - February 02, 2017. (2017)
Molecular counting of membrane receptor subunits with single-molecule localization microscopy. In: Proceedings SPIE 10071, Single Molecule Spectroscopy and Superresolution Imaging X, Vol. Thesis - PhD (9)
2017
Thesis - PhD
Computational Modeling of Membrane Proteins with Sparse Experimental Data. Dissertation, 179 pp., Fachbereich Biochemie, Chemie, Pharmazie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2017)
Thesis - PhD
Mechanistische Einblicke in die Funktionsweise eines Molybdänspeicherproteins. Dissertation, 163 pp., Fachbereich Biochemie, Chemie, Pharmazie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2017)
Thesis - PhD
Comparison of Membrane Proteins Using Computational Programs. Dissertation, 186 pp., Goethe Universität - Fachbereich Biochemie, Chemie und Pharmazie, Frankfurt am Main (2017)
Thesis - PhD
Structural insights into cytochrome bd-type oxygen reductases. Dissertation, 176 pp., Fachbereich Biochemie, Chemie, Pharmazie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2017)
Thesis - PhD
Structure and mechanism of several flavin-based electron bifurcating enzymes. Dissertation, 132 pp., Fachbereich Biowissenschaften, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2017)
Thesis - PhD
Mechanismen des Zucker-Transports: Vergleichende elektrophysiologische Untersuchungen an Transportern der major facilitator superfamily. Dissertation, 261 pp., Johann Wolfgang Goethe-Universität , Fachbereich Biochemie, Chemie, Pharmazie, Frankfurt am Main (2017)
Thesis - PhD
Röntgenstrukturanalyse von Schlüsselenzymen im anaeroben Abbau von Kohlenwasserstoffen. Dissertation, 173 pp., Fachbereich Biochemie, Chemie, Pharmazie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2017)
Thesis - PhD
Tomographic studies of mitochondrial membrane-shaping proteins. Dissertation, 216 pp., Goethe-Universtität, Frankfurt am Main (2017)
Thesis - PhD
Structures and mechanism of secondary active transporters. Dissertation, 194 pp., Fachbereich Biochemie, Chemie und Pharmazie, Goethe-Universität, Frankfurt am Main (2017)
Thesis - Master (13)
2017
Thesis - Master
Lead discovery from the mycobacterial ATP synthase Fo rotor ring and characterisation of its binding site. Master, 75 pp., Goethe-Universität, Frankfurt am Main (2017)
Thesis - Master
Biophysical characterization of the voltage-gated sodium channel NaChBac. Master, 50 pp., Goethe-Universität, Fachbereich Physik, Frankfurt am Main (2017)
Thesis - Master
Mapping the Cytoskeletal Components of the Mammalian Erythrocyte through Electron Microscopy - Biomimetic Implementation in Body Armour. Master, 94 pp., Fachhochschule Kärnten, Villach (2017)
Thesis - Master
Conformational Dynamics of Single-Stranded Nucleic Acids - A Comparison of Molecular Dynamics Simulations to Single-Molecule FRET Experiments. Master, 102 pp., Goethe-Universität, Fachbereich Physik, Frankfurt am Main (2017)
Thesis - Master
Single-particle cryo-EM studies on fatty acid synthase from Saccharomyces cerevisiae. Master, 93 pp., Johann Wolfgang Goethe-Universität, Frankfurt (2017)
Thesis - Master
Electron Microscopic Investigation of Protein Complexes. Master, 74 pp., Institute of Biochemistry, Goethe-Universität, Frankfurt am Main (2017)
Thesis - Master
Predicting Drug-Fragment Binding Sites with Molecular Dynamics Simulations and Markov State Models. Master, 97 pp., Goethe-Universität Frankfurt, Frankfurt am Main (2017)
Thesis - Master
Biophysical analysis of a membrane sensing amphipathic helix in vitro and in silico. Master, 89 pp., Fachbereich Biochemie, Chemie, Pharmazie, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt am Main (2017)